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Abstract

The reported IgG seroprevalence against hepatitis E virus (HEV) in German blood donations is 6.8%, and HEV RNA detected in 0.08%, but documented evidence for HEV transmission is lacking. We identified two donations from a single donor containing 120 IU HEV RNA/mL plasma and 490 IU/mL. An infectious dose of 7,056 IU HEV RNA was transmitted via apheresis platelets to an immunosuppressed patient who developed chronic HEV. Further, transmission was probable in an immunocompetent child.

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/content/10.2807/1560-7917.ES2014.19.21.20812
2014-05-29
2017-11-18
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES2014.19.21.20812
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