1887
Rapid communications Open Access
Like 0

Abstract

To gain insight into the possible origins of the 2009 outbreak of new influenza A(H1N1), we performed two independent analyses of genetic evolution of the new influenza A(H1N1) virus. Firstly, protein homology analyses of more than 400 sequences revealed that this virus most likely evolved from recent swine viruses. Secondly, phylogenetic analyses of 5,214 protein sequences of influenza A(H1N1) viruses (avian, swine and human) circulating in North America for the last two decades (from 1989 to 2009) indicated that the new influenza A(H1N1) virus possesses a distinctive evolutionary trait (genetic distinctness). This appears to be a particular characteristic in pig-human interspecies transmission of influenza A. Thus these analyses contribute to the evidence of the role of pig populations as “mixing vessels” for influenza A(H1N1) viruses.

Loading

Article metrics loading...

/content/10.2807/ese.14.22.19228-en
2009-06-04
2017-10-20
http://instance.metastore.ingenta.com/content/10.2807/ese.14.22.19228-en
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/14/22/art19228-en.htm?itemId=/content/10.2807/ese.14.22.19228-en&mimeType=html&fmt=ahah
Comment has been disabled for this content
Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error