Emergence and dissemination of multidrug resistant clones of Pseudomonas aeruginosa producing VIM-2 metallo-beta-lactamase in Belgium

A Deplano; Hector Rodriguez-Villalobos; Y Glupczynski; P Bogaerts; D Allemeersch; A Grimmelprez; G Mascart; L Bergès; C Laurent; B Byl; MJ Struelens

doi:10.2807/esw.12.03.03114-en

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Emergence and dissemination of multidrug resistant clones of Pseudomonas aeruginosa producing VIM-2 metallo-beta-lactamase in Belgium
A Deplano , Hector Rodriguez-Villalobos , Y Glupczynski , P Bogaerts , D Allemeersch , A Grimmelprez , G Mascart , L Bergès , C Laurent , B Byl , MJ Struelens
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Citation style for this article: Deplano A, Rodriguez-Villalobos Hector, Glupczynski Y, Bogaerts P, Allemeersch D, Grimmelprez A, Mascart G, Bergès L, Laurent C, Byl B, Struelens MJ. Emergence and dissemination of multidrug resistant clones of Pseudomonas aeruginosa producing VIM-2 metallo-beta-lactamase in Belgium. Euro Surveill. 2007;12(3):pii=3114. https://doi.org/10.2807/esw.12.03.03114-en

Abstract

Emergence of carbapenem-hydrolysing metallo-beta-lactamase (MBL) in Pseudomonas aeruginosa has been described worldwide. Infection with MBL-producing strains represents a therapeutic problem due to their resistance to all beta-lactams except monobactams. Several types of MBL enzymes have been identified in P. aeruginosa among which the VIM-type enzymes appear as the most prevalent in Europe with more than 12 allelic variants.