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We report three unrelated cases of Zika virus infection in patients returning from Martinique, Brazil and Colombia respectively, to Montpellier, France. They developed symptoms compatible with a mosquito-borne disease, and serological and molecular investigations indicated a recent Zika virus infection. Considering the recent warning for the likely teratogenicity of Zika virus and the presence of competent mosquito vectors in southern France, these cases highlight the need for awareness of physicians and laboratories in Europe.


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  1. Campos GS, Bandeira AC, Sardi SI. Zika virus outbreak, Bahia, Brazil. Emerg Infect Dis. 2015;21(10):1885-6.  https://doi.org/10.3201/eid2110.150847  PMID: 26401719 
  2. Ministério Da Saûde (Brazil). Monitoramento dos casos de dengue, febre de chikungunya et febre pelo virus zika até a seman Epidémiologica 48, 2015. [Monitoring cases of dengue, chikungunya, zika virus infections as of epidemiological week 48]. Brasília: Ministério Da Saûde. [Accessed 23 December 2015]. Portuguese. Available from: http://portalsaude.saude.gov.br/images/pdf/2015/dezembro/23/2015-049---Dengue-SE-48---para-publica----o-21.12.15.pdf
  3. European Center for Disease Prevention and Control (ECDC). Communicable disease threats report, week 51, 13-19 December 2015. Stockholm: ECDC. 2015. Available from: http://ecdc.europa.eu/en/publications/Publications/Communicable-disease-threats-report-19-dec-2015.pdf
  4. Pan American Health Organization (PAHO). Epidemiological Alert. Neurological syndrome, congenital malformations, and. Zika virus infection. Implications for public health in the Americas Organization. Washington: PAHO. [Accessed 1 Dec 2015]. Available from: http://www.paho.org/hq/index.php?option=com_content&view=category&layout=blog&id=1218&Itemid=2291&lang=fr
  5. Diallo D, Sall AA, Diagne CT, Faye O, Faye O, Ba Y, et al. Zika virus emergence in mosquitoes in southeastern Senegal, 2011. PLoS One. 2014;9(10):e109442.  https://doi.org/10.1371/journal.pone.0109442  PMID: 25310102 
  6. Grard G, Caron M, Mombo IM, Nkoghe D, Mboui Ondo S, Jiolle D, et al. Zika virus in Gabon (Central Africa)--2007: a new threat from Aedes albopictus? PLoS Negl Trop Dis. 2014;8(2):e2681.  https://doi.org/10.1371/journal.pntd.0002681  PMID: 24516683 
  7. European Center for Disease Prevention and Control (ECDC). Communicable disease threats report, week 52, 20-26 December 2015. Stockholm: ECDC. Available from: http://ecdc.europa.eu/en/publications/Publications/Communicable-disease-threats-report-26-dec-2015.pdf.
  8. Zammarchi L, Tappe D, Fortuna C, Remoli ME, Günther S, Venturi G, et al. Zika virus infection in a traveller returning to Europe from Brazil, March 2015. Euro Surveill. 2015;20(23):21153.  https://doi.org/10.2807/1560-7917.ES2015.20.23.21153  PMID: 26084316 
  9. Grandadam M, Caro V, Plumet S, Thiberge JM, Souarès Y, Failloux AB, et al. Chikungunya virus, southeastern France. Emerg Infect Dis. 2011;17(5):910-3.  https://doi.org/10.3201/eid1705.101873  PMID: 21529410 
  10. Marchand E, Prat C, Jeannin C, Lafont E, Bergmann T, Flusin O, et al. Autochthonous case of dengue in France, October 2013. Euro Surveill. 2013;18(50):20661.  https://doi.org/10.2807/1560-7917.ES2013.18.50.20661  PMID: 24342514 
  11. Delisle E, Rousseau C, Broche B, Leparc-Goffart I, L’Ambert G, Cochet A, et al. Chikungunya outbreak in Montpellier, France, September to October 2014. Euro Surveill. 2015;20(17):21108.  https://doi.org/10.2807/1560-7917.ES2015.20.17.21108  PMID: 25955774 
  12. Institut National de Veille Sanitaire (INVS). Surveillance sanitaire en Languedoc-Roussillon. Point épidémiologique au 4 Novembre 2015. [Medical surveillance in Languedoc-Roussillon. Epidemiological point 4 Nov 2015]. Paris: INVS. [Accessed 11 November 2015]. French. Available from: http://www.invs.sante.fr/fr/Publications-et-outils/Points-epidemiologiques/Tous-les-numeros/Languedoc-Roussillon/2015/Surveillance-sanitaire-en-Languedoc-Roussillon.-Point-epidemiologique-au-4-novembre-2015
  13. Wong PS, Li MZ, Chong CS, Ng LC, Tan CH. Aedes (Stegomyia) albopictus (Skuse): a potential vector of Zika virus in Singapore. PLoS Negl Trop Dis. 2013;7(8):e2348.  https://doi.org/10.1371/journal.pntd.0002348  PMID: 23936579 
  14. Petersen EE, Staples JE, Meaney-Delman D, Fischer M, Ellington SR, Callaghan WM, et al. Interim guidelines for pregnant women during a Zika virus outbreak- United States, 2016. MMWR Morb Mortal Wkly Rep. 2016;65(2):30-3.  https://doi.org/10.15585/mmwr.mm6502e1  PMID: 26796813 
  15. Marano G, Pupella S, Vaglio S, Liumbruno GM, Grazzini G. Zika virus and the never-ending story of emerging pathogens and transfusion medicine. Blood Transfus. 2015;5:1-6. PMID: 26674815 

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