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Abstract

Between 1 June and 31 December 2016, 13,023 blood donations from the University Hospital Aachen in Germany were routinely screened for West Nile virus (WNV) RNA using the cobas TaqScreen WNV Test. On 28 September 2016, one blood donor was tested positive. Subsequent analysis revealed an acute Usutu virus (USUV) infection. During the ongoing USUV epizootics in Germany, blood transfusion services, public health authorities and clinicians should be aware of increased human USUV infections.

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/content/10.2807/1560-7917.ES.2017.22.14.30501
2017-04-06
2024-03-28
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2017.22.14.30501
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References

  1. Cadar D, Lühken R, van der Jeugd H, Garigliany M, Ziegler U, Keller M, et al. Widespread activity of multiple lineages of Usutu virus, western Europe, 2016. Euro Surveill. 2017;22(4):30452.  https://doi.org/10.2807/1560-7917.ES.2017.22.4.30452  PMID: 28181903 
  2. Becker N, Jöst H, Ziegler U, Eiden M, Höper D, Emmerich P, et al. Epizootic emergence of Usutu virus in wild and captive birds in Germany. PLoS One. 2012;7(2):e32604.  https://doi.org/10.1371/journal.pone.0032604  PMID: 22389712 
  3. Engel D, Jöst H, Wink M, Börstler J, Bosch S, Garigliany MM, et al. Reconstruction of the Evolutionary History and Dispersal of Usutu Virus, a Neglected Emerging Arbovirus in Europe and Africa. MBio. 2016;7(1):e01938-15.  https://doi.org/10.1128/mBio.01938-15  PMID: 26838717 
  4. Rijks JM, Kik ML, Slaterus R, Foppen R, Stroo A, IJzer J, et al. Widespread Usutu virus outbreak in birds in the Netherlands, 2016. Euro Surveill. 2016;21(45):30391.  https://doi.org/10.2807/1560-7917.ES.2016.21.45.30391  PMID: 27918257 
  5. Weissenböck H, Kolodziejek J, Url A, Lussy H, Rebel-Bauder B, Nowotny N. Emergence of Usutu virus, an African mosquito-borne flavivirus of the Japanese encephalitis virus group, central Europe. Emerg Infect Dis. 2002;8(7):652-6.  https://doi.org/10.3201/eid0807.020094  PMID: 12095429 
  6. Weissenböck H, Bakonyi T, Rossi G, Mani P, Nowotny N. Usutu virus, Italy, 1996. Emerg Infect Dis. 2013;19(2):274-7.  https://doi.org/10.3201/eid1902.121191  PMID: 23347844 
  7. Cavrini F, Gaibani P, Longo G, Pierro AM, Rossini G, Bonilauri P, et al. Usutu virus infection in a patient who underwent orthotropic liver transplantation, Italy, August-September 2009. Euro Surveill. 2009;14(50):19448. PMID: 20070935 
  8. Pecorari M, Longo G, Gennari W, Grottola A, Sabbatini A, Tagliazucchi S, et al. First human case of Usutu virus neuroinvasive infection, Italy, August-September 2009. Euro Surveill. 2009;14(50):19446. PMID: 20070936 
  9. Vilibic-Cavlek T, Kaic B, Barbic L, Pem-Novosel I, Slavic-Vrzic V, Lesnikar V, et al. First evidence of simultaneous occurrence of West Nile virus and Usutu virus neuroinvasive disease in humans in Croatia during the 2013 outbreak. Infection. 2014;42(4):689-95.  https://doi.org/10.1007/s15010-014-0625-1  PMID: 24793998 
  10. Santini M, Vilibic-Cavlek T, Barsic B, Barbic L, Savic V, Stevanovic V, et al. First cases of human Usutu virus neuroinvasive infection in Croatia, August-September 2013: clinical and laboratory features. J Neurovirol. 2015;21(1):92-7.  https://doi.org/10.1007/s13365-014-0300-4  PMID: 25361698 
  11. Grottola A, Marcacci M, Tagliazucchi S, Gennari W, Di Gennaro A, Orsini M, et al. Usutu virus infections in humans: a retrospective analysis in the municipality of Modena, Italy. Clin Microbiol Infect. 2017;23(1):33-7.  https://doi.org/10.1016/j.cmi.2016.09.019  PMID: 27677699 
  12. Allering L, Jöst H, Emmerich P, Günther S, Lattwein E, Schmidt M, et al. Detection of Usutu virus infection in a healthy blood donor from south-west Germany, 2012. Euro Surveill. 2012;17(50):20341. PMID: 23241231 
  13. Gaibani P, Cavrini F, Gould EA, Rossini G, Pierro A, Landini MP, et al. Comparative genomic and phylogenetic analysis of the first Usutu virus isolate from a human patient presenting with neurological symptoms. PLoS One. 2017;23(1):33-7.  https://doi.org/10.1016/j.cmi.2016.09.019  PMID: 23741387 
  14. Goo L, VanBlargan LA, Dowd KA, Diamond MS, Pierson TC. A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis. PLoS Pathog. 2017;13(2):e1006178.  https://doi.org/10.1371/journal.ppat.1006178  PMID: 28207910 
  15. Paul-Ehrlich-Institut. Federal Institute for Vaccines and Biomedicines. Änderung des Bescheides über die Anordnung des Ausschlusses von Blutspendern zur Verhinderung einer möglichen Übertragung des West-Nil-Virus durch nicht pathogen-inaktivierte Blutkomponenten. [Public notification on implementation of risk minimisation measures for blood components concerning transmission of West Nile Virus]. 22 Jan 2014. German. Available from: https://www.pei.de/SharedDocs/Downloads/vigilanz/haemovigilanz/bescheide/2014-04-11-anordnung-ausschluss-blutspender-wnv-ergaenzung.pdf?__blob=publicationFile&v=6
  16. Garigliany M, Linden A, Gilliau G, Levy E, Sarlet M, Franssen M, et al. Usutu virus, Belgium, 2016. Infect Genet Evol. 2017;48:116-9.  https://doi.org/10.1016/j.meegid.2016.12.023  PMID: 28017913 
  17. Lecollinet S, Blanchard Y, Manson C, Lowenski S, Laloy E, Quenault H, et al. Dual Emergence of Usutu Virus in Common Blackbirds, Eastern France, 2015. Emerg Infect Dis. 2016;22(12):2225.  https://doi.org/10.3201/eid2212.161272  PMID: 27869608 
  18. Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, et al. UCSF Chimera--a visualization system for exploratory research and analysis. J Comput Chem. 2004;25(13):1605-12.  https://doi.org/10.1002/jcc.20084  PMID: 15264254 
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