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Abstract

We report four confirmed autochthonously transmitted gonorrhoea cases in Germany in 2025, with isolates exhibiting high-level azithromycin and cefixime resistance. Regarding ceftriaxone, isolates were susceptible for two cases and resistant for two, rendering the later extensively drug-resistant (XDR-NG). Cases, all heterosexual males, were in their late teens to mid-60s. Three isolates were MLST ST18091, with the mosaic -60.001 allele and the 23S rRNA A2045G mutation and were related to an XDR-NG detected in the United Kingdom in 2024.

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/content/10.2807/1560-7917.ES.2025.30.40.2500738
2025-10-09
2025-11-11
/content/10.2807/1560-7917.ES.2025.30.40.2500738
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Autochthonous transmission of extensively drug-resistant Neisseria gonorrhoeae in Germany, 2025
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Regina+Selb&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Selb Regina</a>, <a href="/search?value1=Hana+Tlap%C3%A1k&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tlapák Hana</a>, <a href="/search?value1=Kathleen+Klaper&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Klaper Kathleen</a>, <a href="/search?value1=Susanne+Buder&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Buder Susanne</a>, <a href="/search?value1=Klaus+Jansen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jansen Klaus</a>, <a href="/search?value1=Dagmar+Heuer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Heuer Dagmar</a></span>. Autochthonous transmission of extensively drug-resistant Neisseria gonorrhoeae in Germany, 2025. <a href="/content/ecdc">Euro Surveill.</a> 2025;30(40):pii=2500738. <a href="https://doi.org/10.2807/1560-7917.ES.2025.30.40.2500738" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2025.30.40.2500738</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 19 Sept 2025;&nbsp;&nbsp; <span class="generated">Accepted</span>: 09 Oct 2025 </span> </p>
/content/10.2807/1560-7917.ES.2025.30.40.2500738
/content/10.2807/1560-7917.ES.2025.30.40.2500738
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