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Surveillance Open Access
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Abstract

BACKGROUND

is one of the leading causes of gastrointestinal disease.

AIM

We aimed to investigate trends in the incidence rate of campylobacteriosis in Israel.

METHODS

We collected data on laboratory-confirmed cases of campylobacteriosis reported to the Israel Sentinel Laboratory-Based Surveillance Network (ISLBSN) in 2013–2022. Trends in the incidence rates of campylobacteriosis were evaluated using the Joinpoint software to calculate annual percent change (APC) and by time series analysis auto-regressive integrated moving average model.

RESULTS

Between 2013 and 2022, 43,334 cases of campylobacteriosis were reported to the ISLBSN. The highest incidence rate of campylobacteriosis was observed in children aged 0-4 years (327.8/100,000) and overall, the incidence rate was higher among Jews and others (98.7/100,000) than among Arabs (85.9/100,000). However, the incidence rate among Arabs aged 0-4 years was higher (546.3/100,000) than among Jews and others (316.9/100,000). The incidence rate decreased significantly from 101.7 per 100,000 in 2013 to 79.4 per 100,000 in 2020 (APC = −2.7%) and then increased to 109.5 per 100,000 in 2022 (APC = 13.9%). We identified consistent peaks in incidence rate in April–May, specifically among Jews and others, with no corresponding increase among Arabs. Passover weeks were associated with a significantly higher risk of campylobacteriosis (incidence rate ratio (IRR) = 1.18; 95% CI: 1.12 to 1.23; p < 0.0001) compared with non-Passover weeks.

CONCLUSION

Campylobacteriosis incidence rate in Israel is high, particularly among young children. Collaboration between veterinary and public health authorities and timely public awareness campaigns, especially before holidays, are essential to reduce zoonotic transmission and prevent future peaks.

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2025-12-04
2026-02-07
/content/10.2807/1560-7917.ES.2025.30.48.2500181
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References

  1. World Health Organization (WHO). Campylobacter. Geneva: WHO; 1 May 2020. Available from: https://www.who.int/news-room/fact-sheets/detail/campylobacter
  2. Havelaar AH, Kirk MD, Torgerson PR, Gibb HJ, Hald T, Lake RJ, et al. World Health Organization global estimates and regional comparisons of the burden of foodborne disease in 2010. PLoS Med. 2015;12(12):e1001923.  https://doi.org/10.1371/journal.pmed.1001923  PMID: 26633896 
  3. Hermans D, Van Deun K, Martel A, Van Immerseel F, Messens W, Heyndrickx M, et al. Colonization factors of Campylobacter jejuni in the chicken gut. Vet Res. 2011;42(1):82.  https://doi.org/10.1186/1297-9716-42-82  PMID: 21714866 
  4. Moore JE, Corcoran D, Dooley JSG, Fanning S, Lucey B, Matsuda M, et al. Campylobacter. Vet Res. 2005;36(3):351-82.  https://doi.org/10.1051/vetres:2005012  PMID: 15845230 
  5. Moffatt CRM, Fearnley E, Bell R, Wright R, Gregory J, Sloan-Gardner T, et al. Characteristics of Campylobacter gastroenteritis outbreaks in Australia, 2001 to 2016. Foodborne Pathog Dis. 2020;17(5):308-15.  https://doi.org/10.1089/fpd.2019.2731  PMID: 31738586 
  6. Wiseman A, Berman E, Marantz B, Masury E, Maman O, Pirak M. Baseline survey on the prevalence of Campylobacter in broiler intestines and on broiler carcasses in Israel. Isr J Vet Med. 2017;72(3):3-6.
  7. Bassal R, Lerner L, Valinsky L, Agmon V, Peled N, Block C, et al. Trends in the epidemiology of campylobacteriosis in Israel (1999-2012). Foodborne Pathog Dis. 2016;13(8):448-55.  https://doi.org/10.1089/fpd.2015.2096  PMID: 27203409 
  8. Central Bureau of Statistics (CBS). [Israel population, by population group, religion, age and sex, district and sub-district]. Jerusalem: CBS. [Accessed: 2 Dec 2025]. Hebrew. Available from: https://www.cbs.gov.il/he/Pages/search/yearly.aspx
  9. Fitzgerald C, Whichard J, Nachamkin I. Diagnosis and antimicrobial susceptibility of Campylobacter species. In: Nachamkin I, Szymanski CM, Blaser MJ (editors). Campylobacter. Hoboken: Wiley; 2008. p. 227-43. Available from: https://onlinelibrary.wiley.com/doi/10.1128/9781555815554.ch12
  10. Sagas D, Adler A, Kasher C, Khamaysi K, Strauss M, Chazan B. The effect of the transition to molecular diagnosis on the epidemiology and the clinical characteristics of bacterial gastroenteritis in Northern Israel. Infect Dis (Lond). 2024;56(2):157-63.  https://doi.org/10.1080/23744235.2023.2282713  PMID: 37975631 
  11. Wang G, Clark CG, Taylor TM, Pucknell C, Barton C, Price L, et al. Colony multiplex PCR assay for identification and differentiation of Campylobacter jejuni, C. coli, C. lari, C. upsaliensis, and C. fetus subsp. fetus. J Clin Microbiol. 2002;40(12):4744-7.  https://doi.org/10.1128/JCM.40.12.4744-4747.2002  PMID: 12454184 
  12. Central Bureau of Statistics (CBS). Characterization and classification of geographical units by the socio-economic level of the population, 2015. Jerusalem: CBS; 4 Aug 2019. Available from: https://www.cbs.gov.il/en/publications/Pages/2019/Characterization-and-Classification-of-Geographical-Units-by-the-Socio-Economic-Level-of-the-Population-2015.aspx
  13. National Cancer Institute (NCI). Joinpoint trend analysis software. Bethesda: NCI; 16 Apr 2025. Available from: https://surveillance.cancer.gov/joinpoint
  14. Collins JP, Shah HJ, Weller DL, Ray LC, Smith K, McGuire S, et al. Preliminary incidence and trends of infections caused by pathogens transmitted commonly through food - foodborne diseases active surveillance network, 10 U.S. Sites, 2016-2021. MMWR Morb Mortal Wkly Rep. 2022;71(40):1260-4.  https://doi.org/10.15585/mmwr.mm7140a2  PMID: 36201372 
  15. European Centre for Disease Prevention and Control (ECDC). Campylobacteriosis - annual epidemiological report for 2021. Stockholm: ECDC; 20 Dec 2022. Available from: https://www.ecdc.europa.eu/en/publications-data/campylobacteriosis-annual-epidemiological-report-2021
  16. Liu F, Lee SA, Xue J, Riordan SM, Zhang L. Global epidemiology of campylobacteriosis and the impact of COVID-19. Front Cell Infect Microbiol. 2022;12:979055.  https://doi.org/10.3389/fcimb.2022.979055  PMID: 36519137 
  17. Voetsch AC, Van Gilder TJ, Angulo FJ, Farley MM, Shallow S, Marcus R, et al. FoodNet estimate of the burden of illness caused by nontyphoidal Salmonella infections in the United States. Clin Infect Dis. 2004;38(s3) Suppl 3;S127-34.  https://doi.org/10.1086/381578  PMID: 15095181 
  18. Ziv T, Heymann AD, Azuri J, Leshno M, Cohen D. Assessment of the underestimation of childhood diarrhoeal disease burden in Israel. Epidemiol Infect. 2011;139(9):1379-87.  https://doi.org/10.1017/S0950268810002554  PMID: 21087537 
  19. Bassal R, Keinan-Boker L, Cohen D. A significant decrease in the incidence of shigellosis in Israel during COVID-19 pandemic. Int J Environ Res Public Health. 2021;18(6):3070.  https://doi.org/10.3390/ijerph18063070  PMID: 33809746 
  20. Cohen D, Treygerman O, Ken-Dror S, Sagi O, Strauss M, Parizade M, et al. Twenty-five years of sentinel laboratory-based surveillance of shigellosis in a high-income country endemic for the disease, Israel, 1998 to 2022. Euro Surveill. 2024;29(31):2400022.  https://doi.org/10.2807/1560-7917.ES.2024.29.31.2400022  PMID: 39092530 
  21. Boysen L, Vigre H, Rosenquist H. Seasonal influence on the prevalence of thermotolerant Campylobacter in retail broiler meat in Denmark. Food Microbiol. 2011;28(5):1028-32.  https://doi.org/10.1016/j.fm.2011.02.010  PMID: 21569948 
  22. Abu-Saad K, Murad H, Lubin F, Freedman LS, Ziv A, Alpert G, et al. Jews and Arabs in the same region in Israel exhibit major differences in dietary patterns. J Nutr. 2012;142(12):2175-81.  https://doi.org/10.3945/jn.112.166611  PMID: 23096004 
  23. Bassal R, Ovadia A, Bromberg M, Stein M, Shainberg B, Loewenthal S, et al. Risk factors for sporadic infection with Campylobacter spp. among children in Israel: a case-control study. Pediatr Infect Dis J. 2016;35(3):249-52.  https://doi.org/10.1097/INF.0000000000000989  PMID: 26569191 
  24. Ministry of Agriculture and Food Security. Coming up on Passover 2022 - What is different? The Ministry of Agriculture What types of fish are on the table during the upcoming Passover festival? How much meat will we eat? Beit Dagan: Ministry of Agriculture and Food Security; 10 Apr 2022. Available from: https://www.gov.il/en/pages/passover_cosumption_data_22
  25. Bless PJ, Schmutz C, Mäusezahl D. The recurrent campylobacteriosis epidemic over Christmas and New Year in European countries, 2006-2014. BMC Res Notes. 2017;10(1):266.  https://doi.org/10.1186/s13104-017-2587-8  PMID: 28693589 
  26. Rosner BM, Gassowski M, Albrecht S, Stark K. Investigating the Campylobacter enteritis winter peak in Germany, 2018/2019. Sci Rep. 2021;11(1):22902.  https://doi.org/10.1038/s41598-021-02423-8  PMID: 34824349 
  27. OzFoodNet Working Group. Monitoring the incidence and causes of diseases potentially transmitted by food in Australia: Annual report of the OzFoodNet network, 2013-2015. Commun Dis Intell. 2021;45.
  28. Rushton SP, Sanderson RA, Diggle PJ, Shirley MDF, Blain AP, Lake I, et al. Climate, human behaviour or environment: individual-based modelling of Campylobacter seasonality and strategies to reduce disease burden. J Transl Med. 2019;17(1):34.  https://doi.org/10.1186/s12967-019-1781-y  PMID: 30665426 
  29. Central Bureau of Statistics (CBS). Gaps between Jews and Arabs - 2020-2021, selected data from the society in Israel report no.14 2023. Jerusalem: CBS; 18 Jun 2023. Available from: https://www.cbs.gov.il/en/mediarelease/Pages/2023/Gaps-Between-Jews-and-Arabs-2020-2021-,-Selected-Data-from-the-Society-in-Israel-Report-No-14.aspx
  30. Green MS, Schwartz N, Peer V. Sex differences in campylobacteriosis incidence rates at different ages - a seven country, multi-year, meta-analysis. A potential mechanism for the infection. BMC Infect Dis. 2020;20(1):625.  https://doi.org/10.1186/s12879-020-05351-6  PMID: 32842973 
  31. European Food Safety Authority (EFSA)European Centre for Disease Prevention and Control (ECDC). The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2021-2022. EFSA J. 2024;22(2):e8583. PMID: 38419967 
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