1887
  1. Home
  2. Eurosurveillance
  3. Volume 30, Issue 49, 11/Dec/2025
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

is an emerging dermatophyte increasingly detected in the United Kingdom, often with antifungal resistance. We identified 363 cases between January 2017 and August 2025, with 310 cases (85%) since January 2023. Cases were mostly concentrated in major urban centres and most affected individuals were working-age adults, frequently reporting South Asian ethnicity. The importance of international importation vs domestic transmission remains unclear. Implementing enhanced surveillance would help to identify risk factors and transmission routes to focus prevention efforts.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2025.30.49.2500892
2025-12-11
2026-02-08
/content/10.2807/1560-7917.ES.2025.30.49.2500892
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/30/49/eurosurv-30-49-2.html?itemId=/content/10.2807/1560-7917.ES.2025.30.49.2500892&mimeType=html&fmt=ahah

References

  1. Khurana A, Sharath S, Sardana K, Chowdhary A. Clinico-mycological and therapeutic updates on cutaneous dermatophytic infections in the era of Trichophyton indotineae. J Am Acad Dermatol. 2024;91(2):315-23.  https://doi.org/10.1016/j.jaad.2024.03.024  PMID: 38574764 
  2. Khurana A, Sharath S, Sardana K, Chowdhary A, Panesar S. Therapeutic updates on the management of tinea corporis or cruris in the era of Trichophyton indotineae: separating evidence from hype-a narrative review. Indian J Dermatol. 2023;68(5):525-40.  https://doi.org/10.4103/ijd.ijd_832_23  PMID: 38099117 
  3. Uhrlaß S, Verma SB, Gräser Y, Rezaei-Matehkolaei A, Hatami M, Schaller M, et al. Trichophyton indotineae-an emerging pathogen causing recalcitrant dermatophytoses in India and worldwide-a multidimensional perspective. J Fungi (Basel). 2022;8(7):757.  https://doi.org/10.3390/jof8070757  PMID: 35887512 
  4. Abdolrasouli A, Barton RC, Borman AM. Spread of antifungal-resistant Trichophyton indotineae, United Kingdom, 2017-2024. Emerg Infect Dis. 2025;31(1):192-4.  https://doi.org/10.3201/eid3101.240923  PMID: 39714510 
  5. NHS Digital. Data quality of protected characteristics and other vulnerable groups. Guidance for improving data quality in the Mental Health Services Data Set (MHSDS) and Improving Access to Psychological Therapies (IAPT) Data Set. Chapter 8: Ethnicity 2022. NHS: London. [Accessed: 1 Nov 2025]. Available from: https://digital.nhs.uk/data-and-information/data-collections-and-data-sets/data-sets/mental-health-services-data-set/submit-data/data-quality-of-protected-characteristics-and-other-vulnerable-groups
  6. Office for National Statistics (ONS). Major Towns and Cities –Methodological Note and User Guidance ONS: London; 2025. Available from: https://geoportal.statistics.gov.uk/documents/ons::major-towns-and-cities-methodological-note-and-user-guidance-1/about
  7. Office for National Statistics (ONS). Population estimates for the UK, England, Wales, Scotland and Northern Ireland: mid-2021. ONS: London; 2022. Available from: https://www.ons.gov.uk/peoplepopulationandcommunity/populationandmigration/populationestimates/bulletins/annualmidyearpopulationestimates/mid20212021
  8. Dellière S, Jabet A, Abdolrasouli A. Current and emerging issues in dermatophyte infections. PLoS Pathog. 2024;20(6):e1012258.  https://doi.org/10.1371/journal.ppat.1012258  PMID: 38870096 
  9. Kano R, Kimura U, Kakurai M, Hiruma J, Kamata H, Suga Y, et al. Trichophyton indotineae sp. nov.: a new highly terbinafine-resistant anthropophilic dermatophyte species. Mycopathologia. 2020;185(6):947-58.  https://doi.org/10.1007/s11046-020-00455-8  PMID: 32449054 
  10. Singh A, Masih A, Monroy-Nieto J, Singh PK, Bowers J, Travis J, et al. A unique multidrug-resistant clonal Trichophyton population distinct from Trichophyton mentagrophytes/Trichophyton interdigitale complex causing an ongoing alarming dermatophytosis outbreak in India: Genomic insights and resistance profile. Fungal Genet Biol. 2019;133:103266.  https://doi.org/10.1016/j.fgb.2019.103266  PMID: 31491507 
  11. Chowdhary A, Singh A, Kaur A, Khurana A. The emergence and worldwide spread of the species Trichophyton indotineae causing difficult-to-treat dermatophytosis: A new challenge in the management of dermatophytosis. PLoS Pathog. 2022;18(9):e1010795.  https://doi.org/10.1371/journal.ppat.1010795  PMID: 36173977 
  12. Rhodes J, Hui ST, Dellière S, Summerbell RC, Scott JA, Kaur A, et al. Genomic epidemiology of emerging terbinafine-resistant Trichophyton indotineae. bioRxiv. 2024:2024.10.29.620818.
  13. Uhrlaß S, Panzer R, Koch D, Mütze H, Richter S, Müller L, et al. [Trichophyton mentagrophytes ITS genotype VIII/Trichophyton indotineae in Germany-revisit after 5 years]. Dermatologie (Heidelb). 2025;76(9):551-64. PMID: 40796670 
  14. Uhrlaß S, Koch D, Mütze H, Krüger C, Nenof P. Trichophyton indotineae (Trichophyton mentagrophytes ITS genotype VIII) in Germany – observations from 2018 to July 2025 Trends in Medical Mycology; Bilbao 2025.
  15. McTaggart LR, Cronin K, Ruscica S, Patel SN, Kus JV. Emergence of terbinafine-resistant Trichophyton indotineae in Ontario, Canada, 2014-2023. J Clin Microbiol. 2025;63(1):e0153524.  https://doi.org/10.1128/jcm.01535-24  PMID: 39584838 
  16. Spivack S, Gold JAW, Lockhart SR, Anand P, Quilter LAS, Smith DJ, et al. Potential sexual transmission of antifungal-resistant Trichophyton indotineae. Emerg Infect Dis. 2024;30(4):807-9.  https://doi.org/10.3201/eid3004.240115  PMID: 38437706 
  17. Jabet A, Chiarabini T, Hennequin C, Bouscarat F, Valin N, Cruchet R, et al. Autochthonous transmission of Trichophyton indotineae through sexual contact, France, 2024. Euro Surveill. 2025;30(26):2500416.  https://doi.org/10.2807/1560-7917.ES.2025.30.26.2500416  PMID: 40613126 
  18. Zucker J, Caplan AS, Gunaratne SH, Gallitano SM, Zampella JG, Otto C, et al. Notes from the Field: Trichophyton mentagrophytes Genotype VII - New York City, April-July 2024. MMWR Morb Mortal Wkly Rep. 2024;73(43):985-8.  https://doi.org/10.15585/mmwr.mm7343a5  PMID: 39480750 
  19. Pisano L, Cruciani D, Crotti S, Papini M. Terbinafine-resistant Trichophyton indotineae in two Italian MSM: a new emerging sexually transmissible infection. J Mycol Med. 2025;35(4):101578.  https://doi.org/10.1016/j.mycmed.2025.101578  PMID: 40945299 
  20. Ebert A, Monod M, Salamin K, Burmester A, Uhrlaß S, Wiegand C, et al. Alarming India-wide phenomenon of antifungal resistance in dermatophytes: A multicentre study. Mycoses. 2020;63(7):717-28.  https://doi.org/10.1111/myc.13091  PMID: 32301159 
  21. Mirhendi H, Aboutalebian S, Jahanshiri Z, Rouhi F, Shidfar M-R, Chadeganipour A-S, et al. Increasing and alarming prevalence of Trichophyton indotineae as the primary causal agent of skin dermatophytosis in Iran. Mycoses. 2025;68(1):e70013.  https://doi.org/10.1111/myc.70013  PMID: 39737759 
Rapid emergence of Trichophyton indotineae (Trichophyton mentagrophytes ITS genotype VIII) observed in the United Kingdom, up to August 2025
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Alexandra+Czerniewska&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Czerniewska Alexandra</a>, <a href="/search?value1=Andrew+Borman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Borman Andrew</a>, <a href="/search?value1=Alireza+Abdolrasouli&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Abdolrasouli Alireza</a>, <a href="/search?value1=Emma+L+Budd&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Budd Emma L</a>, <a href="/search?value1=Matthew+C+Fisher&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fisher Matthew C</a>, <a href="/search?value1=Richard+Barton&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Barton Richard</a>, <a href="/search?value1=Kieran+A+Bates&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bates Kieran A</a>, <a href="/search?value1=Jonathan+Lambourne&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lambourne Jonathan</a>, <a href="/search?value1=Alicia+Demirjian&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Demirjian Alicia</a>, <a href="/search?value1=Berit+Muller-Pebody&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Muller-Pebody Berit</a>, <a href="/search?value1=Colin+S+Brown&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brown Colin S</a>, <a href="/search?value1=Maria+Saavedra-Campos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Saavedra-Campos Maria</a>, <a href="/search?value1=Rohini+Manuel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Manuel Rohini</a></span>. Rapid emergence of Trichophyton indotineae (Trichophyton mentagrophytes ITS genotype VIII) observed in the United Kingdom, up to August 2025. <a href="/content/ecdc">Euro Surveill.</a> 2025;30(49):pii=2500892. <a href="https://doi.org/10.2807/1560-7917.ES.2025.30.49.2500892" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2025.30.49.2500892</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 24 Nov 2025;&nbsp;&nbsp; <span class="generated">Accepted</span>: 10 Dec 2025 </span> </p>
/content/10.2807/1560-7917.ES.2025.30.49.2500892
/content/10.2807/1560-7917.ES.2025.30.49.2500892
Loading

Data & Media loading...

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error