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2025 theme: Vaccines

Abstract

BACKGROUND

Vaccination of residents and healthcare workers (HCWs) against influenza in nursing homes is an important prevention strategy.

AIM

To describe trends in influenza vaccination coverage (VC) among HCWs working in nursing homes in France and measures implemented to support vaccination campaigns from 2007 to 2025, and to identify effectiveness of these measures.

METHODS

We analysed data from seven nationwide cross-sectional studies conducted between seasons 2007/08 and 2024/25 and performed multivariate analysis using negative binomial regressions, to identify determinants.

RESULTS

National influenza VC among HCWs decreased from 37.2% (95% CI: 35.7–39.4) in 2007/08 to 24.2% (95% CI: 23.2–25.1) in 2024/25 (mean: 39,740 HCWs per season, 6 seasons). Vaccination coverage disparities by category of HCWs (2024/25 VC of physicians: 56.3%; nurses: 34.2%; nursing assistants: 19.3%) were observed throughout the period. Measures to promote influenza vaccination were less frequently implemented over time: support of vaccination campaigns by the management team (from 2018/19: 89% to 2024/25: 52%), implementation of collective (68% to 49%) or individual information sessions (19% to 9%), distribution of information on influenza vaccines (64% to 53%) or influenza (83% to 69%). Seven measures exhibited effectiveness in 2018/19 compared to only four in 2024/25, which had less effectiveness. Management teams highlighted the strong reluctance of HCWs to receive influenza vaccination.

CONCLUSIONS

Influenza VC among HCWs in nursing homes is marked by disparities among professional categories. To mitigate the decline in VC among HCWs, it is essential to implement effective measures to support the campaigns.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
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2026-03-26
2026-04-18
/content/10.2807/1560-7917.ES.2026.31.12.2500628
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References

  1. Hansen CL, Viboud C, Chaves SS. The use of death certificate data to characterize mortality associated with respiratory syncytial virus, unspecified bronchiolitis, and influenza in the United States, 1999-2018. J Infect Dis. 2022;226(Suppl 2):S255-66.  https://doi.org/10.1093/infdis/jiac187  PMID: 35968872 
  2. Thompson WW, Shay DK, Weintraub E, Brammer L, Bridges CB, Cox NJ, et al. Influenza-associated hospitalizations in the United States. JAMA. 2004;292(11):1333-40.  https://doi.org/10.1001/jama.292.11.1333  PMID: 15367555 
  3. Demicheli V, Jefferson T, Di Pietrantonj C, Ferroni E, Thorning S, Thomas RE, et al. Vaccines for preventing influenza in the elderly. Cochrane Database Syst Rev. 2018;2(2):CD004876. PMID: 29388197 
  4. Monto AS, Rotthoff J, Teich E, Herlocher ML, Truscon R, Yen HL, et al. Detection and control of influenza outbreaks in well-vaccinated nursing home populations. Clin Infect Dis. 2004;39(4):459-64.  https://doi.org/10.1086/422646  PMID: 15356805 
  5. Vaux S, Poujol I, Bonmarin I, Lévy-Bruhl D, Desenclos JC. Surveillance of lower respiratory tract infections outbreaks in nursing homes in France. Eur J Epidemiol. 2009;24(3):149-55.  https://doi.org/10.1007/s10654-009-9315-1  PMID: 19199055 
  6. Bernard-Stoecklin S.Équipes de surveillance de la grippe. Surveillance de la grippe en France hexagonale, saison 2024-2025. (Influenza surveillance in mainland France, 2024-2025 season). Bull Epidemiol Hebd (Paris). 2025; (17):312-30. French. Available from: https://beh.santepubliquefrance.fr/beh/2025/17/2025_17_1.html
  7. Ahmed F, Lindley MC, Allred N, Weinbaum CM, Grohskopf L. Effect of influenza vaccination of healthcare personnel on morbidity and mortality among patients: systematic review and grading of evidence. Clin Infect Dis. 2014;58(1):50-7.  https://doi.org/10.1093/cid/cit580  PMID: 24046301 
  8. Thomas RE, Jefferson T, Lasserson TJ, Earnshaw S. Influenza vaccination for healthcare workers who care for people aged 60 or older living in long-term care institutions. Cochrane Database Syst Rev. 2025;2(2):CD005187. PMID: 40013540 
  9. Haut Conseil de la santé Publique. Objectifs de santé publique. Evaluation des objectifs de la loi du 9 août 2004. [Public Health Objectives: Evaluation of the Objectives of the Law of August 9, 2004]. Paris: Haute Autorité de Santé; 2010. French. Available from: https://www.hcsp.fr/explore.cgi/avisrapportsdomaine?clefr=133
  10. Vaux S, Fonteneau L, Venier AG, Gautier A, Soing Altrach S, Parneix P, et al. Influenza vaccination coverage of professionals working in nursing homes in France and related determinants, 2018-2019 season: a cross-sectional survey. BMC Public Health. 2022;22(1):1049.  https://doi.org/10.1186/s12889-022-13412-5  PMID: 35614428 
  11. Vaux S, Noël D, Fonteneau L, Guthmann JP, Lévy-Bruhl D. Influenza vaccination coverage of healthcare workers and residents and their determinants in nursing homes for elderly people in France: a cross-sectional survey. BMC Public Health. 2010;10(1):159.  https://doi.org/10.1186/1471-2458-10-159  PMID: 20338028 
  12. Haviari S, Bénet T, Saadatian-Elahi M, André P, Loulergue P, Vanhems P. Vaccination of healthcare workers: A review. Hum Vaccin Immunother. 2015;11(11):2522-37.  https://doi.org/10.1080/21645515.2015.1082014  PMID: 26291642 
  13. Neufeind J, Wenchel R, Boedeker B, Wicker S, Wichmann O. Monitoring influenza vaccination coverage and acceptance among health-care workers in German hospitals - results from three seasons. Hum Vaccin Immunother. 2021;17(3):664-72.  https://doi.org/10.1080/21645515.2020.1801072  PMID: 33124954 
  14. Papageorgiou C, Mazeri S, Karaiskakis M, Constantinou D, Nikolaides C, Katsouris S, et al. Exploring vaccination coverage and attitudes of health care workers towards influenza vaccine in Cyprus. Vaccine. 2022;40(12):1775-82.  https://doi.org/10.1016/j.vaccine.2022.02.020  PMID: 35168841 
  15. Garcell HG, Ramirez EC. Influenza immunization coverage for healthcare workers in a community hospital in Qatar (2011-2012 and 2012-2013 seasons). J Infect Public Health. 2014;7(1):70-2.  https://doi.org/10.1016/j.jiph.2013.06.007  PMID: 24284023 
  16. Lymon H, Meng L, Reses HE, Barbre K, Dubendris H, Shafi S, et al. Declines in influenza vaccination coverage among health care personnel in acute care hospitals during the COVID-19 pandemic - United States, 2017-2023. MMWR Morb Mortal Wkly Rep. 2023;72(45):1244-7.  https://doi.org/10.15585/mmwr.mm7245a6  PMID: 37943698 
  17. European Centre for Disease Prevention and Control (ECDC). Seasonal influenza vaccination and coverage rates in EU/EEA member states. An overview of vaccination recommendations for 2021-22 and coverage rates for the 2018-19 to 2020-21 influenza seasons. Surveillance and monitoring. / 30 pages. Stockholm: ECDC; 2023. Available from: https://www.ecdc.europa.eu/en/publications-data/seasonal-influenza-vaccination-recommendations-and-coverage-rates-eueea-member.
  18. Guerrero-Soler M, Gras-Valenti P, Platas-Abenza G, Sánchez-Payá J, Sanjuan-Quiles Á, Chico-Sánchez P, On Behalf Of The Preventive Medicine Vaccination Work Group. Impact of the COVID-19 Pandemic on Influenza Vaccination Coverage of Healthcare Personnel in Alicante, Spain. Vaccines (Basel). 2024;12(4):370.  https://doi.org/10.3390/vaccines12040370  PMID: 38675752 
  19. Israel Ministry of Health. Quality and Safety Division, Health Services Research Department. Influenza vaccination of healthcare workers in Israel report for 2014-2021. Jerusalem: Israel Ministry of Health; 2022. Available from: https://www.gov.il/BlobFolder/reports/flu-report-medical-staff-2017-2021/he/files_publications_units_qauality_and_patient_safety_flu-report-medical-staff-2017-2021-Executive-Summary.pdf.
  20. Santé publique France. Quelle est la couverture vaccinale contre la COVID-19 chez des professionnels exerçant dans le domaine de la santé et des résidents en ESMS [What is the vaccination coverage against COVID-19 among healthcare professionals and residents in nursing homes?]. Saison 2021-2022. Le point sur: SpF; 2022. https://www.santepubliquefrance.fr/maladies-et-traumatismes/maladies-et-infections-respiratoires/infection-a-coronavirus/documents/enquetes-etudes/quelle-est-la-couverture-vaccinale-contre-la-covid-19-chez-des-professionnels-exercant-dans-le-domaine-de-la-sante-et-des-residents-en-esms.-point2.
  21. Vaux S, Fonteneau L, Péfau M, Venier AG, Gautier A, Altrach SS, et al. Vaccination against influenza, measles, pertussis and varicella in workers in healthcare facilities in France: A national cross-sectional study in 2019. Vaccine. 2023;41(3):812-20.  https://doi.org/10.1016/j.vaccine.2022.12.023  PMID: 36528442 
  22. Papageorgiou C, Mazeri S, Karaiskakis M, Constantinou D, Nikolaides C, Katsouris S, et al. Exploring vaccination coverage and attitudes of health care workers towards influenza vaccine in Cyprus. Vaccine. 2022;40(12):1775-82.  https://doi.org/10.1016/j.vaccine.2022.02.020  PMID: 35168841 
  23. Anselem O, Charlier C, Viaud M, Lelong N, Vaux S, Launay O, et al. Barriers to influenza vaccination during pregnancy in France: A national population-based study. Vaccine. 2025;47:126671.  https://doi.org/10.1016/j.vaccine.2024.126671  PMID: 39754833 
  24. Dilange L, El Belghiti FA, Demiguel V, Anselem O, Regnault N, Le Ray C, et al. Pertussis vaccination coverage in women at two months postpartum and associated factors in France, National Perinatal Survey 2021. Vaccine. 2025;43(Pt 1):126502.  https://doi.org/10.1016/j.vaccine.2024.126502  PMID: 39520895 
  25. Vaux S, Gautier A, Fonteneau L, Gault G, Gagnière B, Soullier N, et al. Couverture vaccinale contre la grippe chez les personnes de 65 à 85 ans et étude des déterminants, enquête nationale, Baromètre de Santé publique France 2021.(Vaccination coverage against influenza among people aged 65 to 85 years and study of determinants, national survey, Public Health France Health Barometer 2021). Bull Epidemiol Hebd (Paris). 2025; (2):16-23. French. Available from: http://beh.santepubliquefrance.fr/beh/2025/2/2025_2_1.html
  26. Oudin Doglioni D, Gagneux-Brunon A, Gauchet A, Bruel S, Olivier C, Pellissier G, et al. Psychometric validation of a 7C-model of antecedents of vaccine acceptance among healthcare workers, parents and adolescents in France. Sci Rep. 2023;13(1):19895.  https://doi.org/10.1038/s41598-023-46864-9  PMID: 37963903 
  27. Vaux S, Gautier A, Nassany O, Bonmarin I. Vaccination acceptability in the French general population and related determinants, 2000-2021. Vaccine. 2023;41(42):6281-90.  https://doi.org/10.1016/j.vaccine.2023.08.062  PMID: 37673718 
  28. Talbot TR, Schimmel R, Swift MD, Rolando LA, Johnson RT, Muscato J, et al. Expanding mandatory healthcare personnel immunization beyond influenza: Impact of a broad immunization program with enhanced accountability. Infect Control Hosp Epidemiol. 2021;42(5):513-8.  https://doi.org/10.1017/ice.2020.1266  PMID: 33168113 
  29. Haute Autorité de Santé. Actualisation des recommandations et obligations vaccinales des professionnels. Volet 2/2: coqueluche, grippe saisonnière, hépatite A, rougeole, oreillons, rubéole, varicelle. [Updating the recommendations and vaccination obligations for professionals. Part 2/2: pertussis, seasonal influenza, hepatitis A, measles, mumps, rubella, varicella]. Paris: Haute Autorité de Santé; 2023. French. Available from: https://www.has-sante.fr/jcms/p_3456351/en/actualisation-des-recommandations-et-obligations-vaccinales-des-professionnels.
  30. Vaux S, Fonteneau L, Péfau M, Venier AG, Gautier A, Altrach SS, et al. Acceptability of mandatory vaccination against influenza, measles, pertussis and varicella by workers in healthcare facilities: a national cross-sectional study, France, 2019. Arch Public Health. 2023;81(1):51.  https://doi.org/10.1186/s13690-023-01069-4  PMID: 37020228 
  31. Lytras T, Kopsachilis F, Mouratidou E, Papamichail D, Bonovas S. Interventions to increase seasonal influenza vaccine coverage in healthcare workers: A systematic review and meta-regression analysis. Hum Vaccin Immunother. 2016;12(3):671-81.  https://doi.org/10.1080/21645515.2015.1106656  PMID: 26619125 
Decreases in influenza vaccination coverage among nursing home healthcare workers and in measures to promote influenza vaccination, France, 2007/08 to 2024/25
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Remi+Hanguehard&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hanguehard Remi</a>, <a href="/search?value1=Laure+Fonteneau&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fonteneau Laure</a>, <a href="/search?value1=Nathalie+Bonnet&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bonnet Nathalie</a>, <a href="/search?value1=Daniel+Levy-Bruhl&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Levy-Bruhl Daniel</a>, <a href="/search?value1=Isabelle+Parent-du-Ch%C3%A2telet&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Parent-du-Châtelet Isabelle</a>, <a href="/search?value1=Sophie+Vaux&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vaux Sophie</a></span>. Decreases in influenza vaccination coverage among nursing home healthcare workers and in measures to promote influenza vaccination, France, 2007/08 to 2024/25. <a href="/content/ecdc">Euro Surveill.</a> 2026;31(12):pii=2500628. <a href="https://doi.org/10.2807/1560-7917.ES.2026.31.12.2500628" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2026.31.12.2500628</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 12 Aug 2025;&nbsp;&nbsp; <span class="generated">Accepted</span>: 10 Nov 2025 </span> </p>
/content/10.2807/1560-7917.ES.2026.31.12.2500628
/content/10.2807/1560-7917.ES.2026.31.12.2500628
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