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SDG 3: Antimicrobial resistance

Abstract

producing OXA-181 was detected from a patient in Ireland in October 2025. The isolate had a meropenem minimum inhibitory concentration (MIC) of 0.12 mg/L. Carbapenemase production was detected by lateral flow immunoassay. The sequence type was ST245 and closely related to sequences previously reported from Ireland and other countries but not previously linked to presence of the gene Carbapenemase production in spp. has implications for laboratory detection and empiric treatment.

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/content/10.2807/1560-7917.ES.2026.31.18.2600351
2026-05-07
2026-06-10
/content/10.2807/1560-7917.ES.2026.31.18.2600351
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References

  1. European Centre for Disease Prevention and Control (ECDC). Rapid risk assessment: Increase in extensively-drug resistant Shigella sonnei infections in men who have sex with men in the EU/EEA and the UK – 23 February 2022. Stockholm: ECDC; 2022. Available from: https://www.ecdc.europa.eu/en/publications-data/rapid-risk-assessment-increase-extensively-drug-resistant-shigella-sonnei
  2. Health Service Executive (HSE) Public Health-Health Protection. Recommendations on aspects of management of shigellosis in Ireland in the context of current antimicrobial resistant Shigella species associated with gay, bisexual and men who have sex with men (gbMSM) Version 1. Dublin: HSE Public Health-Health Protection; 2024. Available from: https://www.hpsc.ie/a-z/gastroenteric/shigellosis/guidancepublications/Recommendations%20of%20aspects%20of%20management%20of%20shigellosis.pdf
  3. European Centre for Disease Prevention and Control (ECDC). Spread of multidrug-resistant Shigella in EU/EEA among gay, bisexual and other men who have sex with men. – 18 July 2023. Stockholm: ECDC; 2023. Available from: https://www.ecdc.europa.eu/en/news-events/spread-multidrug-resistant-shigella-eueea-among-gay-bisexual-and-other-men-who-have-sex
  4. Logan N, Birhane MG, McDonald SL, Alarcón J, Amador S, Anand M, et al. , XDR Shigella Working Group. Emergence of extensively drug-resistant shigellosis — United States, 2011–2023. MMWR Morb Mortal Wkly Rep. 2026;75(13):173-8.  https://doi.org/10.15585/mmwr.mm7513a1  PMID: 41955161 
  5. Dhabaan G, Jamal H, Ouellette D, Alexander S, Arane K, Campigotto A, et al. Detection of OXA-181 carbapemenase in Shigella flexneri. Emerg Infect Dis. 2024;30(5):1048-50.  https://doi.org/10.3201/eid3005.231558  PMID: 38666725 
  6. Abdelaziz NA. Phenotype-genotype correlations among carbapenem-resistant Enterobacterales recovered from four Egyptian hospitals with the report of SPM carbapenemase. Antimicrob Resist Infect Control. 2022;11(1):13.  https://doi.org/10.1186/s13756-022-01061-7  PMID: 35063019 
  7. Thamizhmani R, Rhagavan R, Sugunan AP, Vijayachari P. VIM- and IMP-type metallo-β-lactamase-producing Shigella spp. in childhood diarrhea from Andaman Islands. Infect Dis (Lond). 2015;47(10):749-50.  https://doi.org/10.3109/23744235.2015.1022874  PMID: 25768231 
  8. European Committee on Antimicrobial Susceptibility Testing (EUCAST). Clinical Breakpoint Tables. Version 16.0. Växjö: EUCAST; 2025. Available from: https://www.eucast.org/bacteria/clinical-breakpoints-and-interpretation/clinical-breakpoint-tables
A case of carbapenamase production in Shigella flexneri isolated in Ireland, 2025
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Christina+Clarke&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Clarke Christina</a>, <a href="/search?value1=Alma+Tuohy&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tuohy Alma</a>, <a href="/search?value1=Erica+Duignan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Duignan Erica</a>, <a href="/search?value1=Paul+Mullane&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mullane Paul</a>, <a href="/search?value1=Ann+Marie+Carolan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Carolan Ann Marie</a>, <a href="/search?value1=Orla+Craig&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Craig Orla</a>, <a href="/search?value1=Georgios+Miliotis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Miliotis Georgios</a>, <a href="/search?value1=Christina+Dillon&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Dillon Christina</a>, <a href="/search?value1=Martin+Cormican&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cormican Martin</a></span>. A case of carbapenamase production in Shigella flexneri isolated in Ireland, 2025. <a href="/content/ecdc">Euro Surveill.</a> 2026;31(18):pii=2600351. <a href="https://doi.org/10.2807/1560-7917.ES.2026.31.18.2600351" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2026.31.18.2600351</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 22 Apr 2026;&nbsp;&nbsp; <span class="generated">Accepted</span>: 06 May 2026 </span> </p>
/content/10.2807/1560-7917.ES.2026.31.18.2600351
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