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SDG 3: Antimicrobial resistance

Abstract

A penicillin-resistant group B streptococcal (GBS) strain was identified in Italy, after isolation from the blood culture of a patient in their 80s with comorbidities. The isolate was multidrug-resistant and demonstrated by genome sequencing to be of serotype Ia, sequence type 23, and to possess the gene. Known and new point mutations were detected in the penicillin-binding-protein genes 2a and 2x. Although sporadic, penicillin-resistance in GBS is a serious concern for prophylaxis and therapy, so continued GBS surveillance remains important.

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2026-05-21
2026-06-10
/content/10.2807/1560-7917.ES.2026.31.20.2600374
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First case of penicillin-resistant Streptococcus agalactiae (group B Streptococcus) isolated from an adult patient in Italy, February 2026
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Roberta+Creti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Creti Roberta</a>, <a href="/search?value1=Giovanni+Gherardi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gherardi Giovanni</a>, <a href="/search?value1=Monica+Imperi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Imperi Monica</a>, <a href="/search?value1=Andrea+Zappavigna&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zappavigna Andrea</a>, <a href="/search?value1=Gabriella+Tocci&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Tocci Gabriella</a>, <a href="/search?value1=Nicol%C3%B2+Rossi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rossi Nicolò</a>, <a href="/search?value1=Filippo+Trapani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Trapani Filippo</a>, <a href="/search?value1=Giovanna+Alfarone&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alfarone Giovanna</a>, <a href="/search?value1=Ilaria+Marani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Marani Ilaria</a>, <a href="/search?value1=Anna+Teresa+Palamara&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Palamara Anna Teresa</a>, <a href="/search?value1=Giuliana+Lo+Cascio&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lo Cascio Giuliana</a></span>. First case of penicillin-resistant Streptococcus agalactiae (group B Streptococcus) isolated from an adult patient in Italy, February 2026. <a href="/content/ecdc">Euro Surveill.</a> 2026;31(20):pii=2600374. <a href="https://doi.org/10.2807/1560-7917.ES.2026.31.20.2600374" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2026.31.20.2600374</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 04 May 2026;&nbsp;&nbsp; <span class="generated">Accepted</span>: 21 May 2026 </span> </p>
/content/10.2807/1560-7917.ES.2026.31.20.2600374
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