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SDG 3: Antimicrobial resistance

Abstract

In seven EU/EEA countries, the emergence of NDM-5-producing ST1344 among patients has been detected. In minimum spanning tree analysis of core genome-multilocus sequence-typing (cgMLST) profiles, isolates cluster with ≤ 4 allelic differences. The outbreak includes 57 cases (29 female/28 male; median age: 73 years), which occurred between March 2025 and April 2026. Many were hospitalised (n = 45), some with extensive prior medical treatment, and only three reported travel abroad. A cross-border investigation, including coordinated exposure questionnaires, has not yet identified a source.

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/content/10.2807/1560-7917.ES.2026.31.25.2600460
2026-06-25
2026-07-16
/content/10.2807/1560-7917.ES.2026.31.25.2600460
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Ongoing multi-country outbreak of carbapenem-resistant Enterobacter hormaechei ST1344 carrying bla NDM-5 in the European Union/European Economic Area, March 2025 to April 2026
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Louise+Roer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Roer Louise</a>, <a href="/search?value1=Mirco+Sandfort&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sandfort Mirco</a>, <a href="/search?value1=Sebastian+Haller&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Haller Sebastian</a>, <a href="/search?value1=Sarah+A+Roth&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Roth Sarah A</a>, <a href="/search?value1=Lisa-Marie+H%C3%B6fken&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Höfken Lisa-Marie</a>, <a href="/search?value1=Soheila+Javadi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Javadi Soheila</a>, <a href="/search?value1=N%C3%BAria+Balanza&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Balanza Núria</a>, <a href="/search?value1=Amelie+Friedsam&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Friedsam Amelie</a>, <a href="/search?value1=Silver+A+Wolf&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wolf Silver A</a>, <a href="/search?value1=Claus+%C3%98stergaard&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Østergaard Claus</a>, <a href="/search?value1=Monica+T+Y+Wong&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wong Monica T Y</a>, <a href="/search?value1=Joanna+Lis-T%C3%B8nder&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lis-Tønder Joanna</a>, <a href="/search?value1=Annelot+F+Schoffelen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schoffelen Annelot F</a>, <a href="/search?value1=Martin+Cormican&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cormican Martin</a>, <a href="/search?value1=Lone+Jannok+Porsbo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Porsbo Lone Jannok</a>, <a href="/search?value1=Christina+Clarke&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Clarke Christina</a>, <a href="/search?value1=Henrik+Hasman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hasman Henrik</a>, <a href="/search?value1=Heidrun+Kerschner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kerschner Heidrun</a>, <a href="/search?value1=Anette+M+Hammerum&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hammerum Anette M</a>, <a href="/search?value1=Rainer+Hart&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hart Rainer</a>, <a href="/search?value1=%C3%98rjan+Samuelsen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Samuelsen Ørjan</a>, <a href="/search?value1=Miriam+Sare&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sare Miriam</a>, <a href="/search?value1=Marie+Meo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Meo Marie</a>, <a href="/search?value1=Anne-Sophie+Lagneaux&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lagneaux Anne-Sophie</a>, <a href="/search?value1=Monique+Perrin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Perrin Monique</a>, <a href="/search?value1=Vilhelm+M%C3%BCller&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Müller Vilhelm</a>, <a href="/search?value1=Sandra+Witteveen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Witteveen Sandra</a>, <a href="/search?value1=Sabine+C+de+Greeff&option1=author&noRedirect=true" class="nonDisambigAuthorLink">de Greeff Sabine C</a>, <a href="/search?value1=Daan+W+Notermans&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Notermans Daan W</a>, <a href="/search?value1=Olov+Svartstr%C3%B6m&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Svartström Olov</a>, <a href="/search?value1=Erik+Alm&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alm Erik</a>, <a href="/search?value1=Marius+Linkevicius&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Linkevicius Marius</a>, <a href="/search?value1=Anke+Kohlenberg&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kohlenberg Anke</a>, <a href="/search?value1=Antoni+P+A+Hendrickx&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hendrickx Antoni P A</a></span>. Ongoing multi-country outbreak of carbapenem-resistant Enterobacter hormaechei ST1344 carrying bla NDM-5 in the European Union/European Economic Area, March 2025 to April 2026. <a href="/content/ecdc">Euro Surveill.</a> 2026;31(25):pii=2600460. <a href="https://doi.org/10.2807/1560-7917.ES.2026.31.25.2600460" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2026.31.25.2600460</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 26 May 2026;&nbsp;&nbsp; <span class="generated">Accepted</span>: 25 Jun 2026 </span> </p>
/content/10.2807/1560-7917.ES.2026.31.25.2600460
/content/10.2807/1560-7917.ES.2026.31.25.2600460
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