- Home
- Collections
- Andes hantavirus
Andes hantavirus
Collection Contents
4 results
-
-
Transient Andes orthohantavirus RNA detection in an asymptomatic healthcare worker following indirect exposure during hospital care of an imported case, the Netherlands, 2026
More LessAlma Tostmann , Annelies Brilman , Loek Smits , Bram Huizer , Chantal Reusken , Margreet te Wierik , Helma Ruijs , Corine Geurts van Kessel , Marloes Mattijssen , Manon Tingen-Wieland , Olga Coenen-Bouwman , Matthew McCall , Esmée Ruizendaal , Ingrid van Schalen , Karin Ellen Veldkamp , Rosa van Mansfeld , Annemiek van der Eijk , Heiman FL Wertheim and Chantal P RoversFollowing an outbreak of Andes hantavirus (ANDV) infections on a cruise ship in May 2026, a healthcare worker not directly involved in caring for an imported ANDV case in the Netherlands had a single low-positive ANDV PCR result. The healthcare worker remained asymptomatic, showed no seroconversion, and all subsequent samples tested negative. We describe a retrospective investigation, including detailed reconstruction of potential transmission routes. Our finding may indicate that asymptomatic ANDV infections with low-level viraemia can occur after indirect exposure.
-
-
-
Andes virus outbreak linked to expedition cruise ship travel, multi-country investigation and response, April to June 2026
More LessOda Everdina van den Berg , UKHSA ANDV Team , Ettore Severi , Freddy Mutoka-Banza , Michele van Vugt , Esther M Schadd , María Cruz Calvo Reyes , Laura Santos Larrégola , Pedro Valdivia Prieto , François-Xavier Lescure , Mark A Cachia , Mayank Singal , Mirko Faber , Walter Zingg , Nazir Ahmed Ismail , Margreet JM te Wierik , Tjalling Leenstra , Chantal Reusken , Susan van den Hof and the International ANDV teamAs at 9 July 2026††, 13 cases (12 confirmed and one probable) of Andes orthohantavirus have been reported (case fatality: 23%), linked to the Dutch-flagged expedition cruise ship m/v Hondius. The event involved individuals from 23 nationalities and required medical evacuation, repatriation, coordinated international contact tracing, isolation, quarantine and clinical and laboratory testing follow-up. To date, all cases have been passengers (10/121; 8%) or crew members (3/61; 5%). Ongoing monitoring and investigations aim to clarify the source of the outbreak, identify risk factors and prevent further spread.
-
-
-
Scenario analysis for potential community spread of Andes virus (ANDV)
More LessValentina Marziano , Alfredo De Bellis , Martina Del Manso , Antonino Bella , Alberto Mateo Urdiales , Carla Molina Grané , Francesco Menegale , Lorenzo Lucchini , Mattia Manica , Sobha Pilati , Daniele Mipatrini , Flavia Riccardo , Giorgio Guzzetta , Piero Poletti , Anna Teresa Palamara , Patrizio Pezzotti and Stefano MerlerWe simulated the potential community spread of Andes virus (ANDV) following the introduction of a single infectious individual in a generic population, based on epidemiological parameters derived from a human-to-human historical outbreak. Under current available evidence, our analyses suggest that, within 4 months from the index case’s symptom onset, the expected outbreak size is unlikely to exceed 50 cases, with a high probability of epidemic extinction, particularly when > 50% cases are effectively isolated from the start of the outbreak.
-
-
-
Why Andes hantavirus is not the next SARS-CoV-2: contrasting viral shedding, transmissibility and genomic patterns
More LessA cruise ship-associated Andes hantavirus outbreak has raised questions usually associated with respiratory viruses, including transmissibility and pandemic risk. Although Andes virus may enter through the respiratory route, cause severe respiratory disease and under close contact spread between humans, it differs fundamentally from SARS-CoV-2. The ecology is rodent-borne, pathogenesis is vascular, diagnosis is centred on blood PCR and serology, and genetic diversity is mainly shaped by reservoir ecology and geography rather than by sustained human-to-human transmission and immune selection.
-