- Home
- Eurosurveillance
- Previous Issues
- Volume 30, Issue 48, 04/Dec/2025
Eurosurveillance - Volume 30, Issue 48, 04 December 2025
Volume 30, Issue 48, 2025
- Rapid communication
-
-
-
Expansion of influenza A(H1N1)pdm09 NA:S247N viruses with reduced susceptibility to oseltamivir, Catalonia, Spain, and in Europe, July to October 2025
Narcís Saubi , Cristina Andrés , Ignasi Prats-Méndez , Alejandra González-Sánchez , Alysa Davtyan , Rodrigo Vásquez-Mercado , Ariadna Rando , Patricia Nadal , Juliana Esperalba , Maria Arnedo , Marina Vicente , Eva Balada , Jacobo Mendioroz , María Carmen Martín , Karen García-Camuñas , Raquel Vaz , Adrià Najarro , Susana Bernalte , Nieves Larrosa , Andrés Antón and on behalf of the SIVIC Infectious diseases sentinel networkMore LessBetween July and October 2025, among the total 117 influenza A(H1N1)pdm09 strains characterised in Catalonia, 20% to 100% per week were carrying the NA:S247N substitution. The mutation, conferring reduced susceptibility to oseltamivir, was phenotypically confirmed (IC50 between 0.82 and 1.63 nM, compared to median IC50 of 0.3 nM for susceptible strains). An increased proportion of S247N variants was also observed in sequence data (10,944 sequences) from other parts of Spain and five of 35 submitting countries across Europe.
-
- Top
-
- Surveillance
-
-
-
Trends in incidence and epidemiological characteristics of campylobacteriosis, Israel, 2013 to 2022
More LessBACKGROUNDCampylobacter is one of the leading causes of gastrointestinal disease.
AIMWe aimed to investigate trends in the incidence rate of campylobacteriosis in Israel.
METHODSWe collected data on laboratory-confirmed cases of campylobacteriosis reported to the Israel Sentinel Laboratory-Based Surveillance Network (ISLBSN) in 2013–2022. Trends in the incidence rates of campylobacteriosis were evaluated using the Joinpoint software to calculate annual percent change (APC) and by time series analysis auto-regressive integrated moving average model.
RESULTSBetween 2013 and 2022, 43,334 cases of campylobacteriosis were reported to the ISLBSN. The highest incidence rate of campylobacteriosis was observed in children aged 0-4 years (327.8/100,000) and overall, the incidence rate was higher among Jews and others (98.7/100,000) than among Arabs (85.9/100,000). However, the incidence rate among Arabs aged 0-4 years was higher (546.3/100,000) than among Jews and others (316.9/100,000). The incidence rate decreased significantly from 101.7 per 100,000 in 2013 to 79.4 per 100,000 in 2020 (APC = −2.7%) and then increased to 109.5 per 100,000 in 2022 (APC = 13.9%). We identified consistent peaks in incidence rate in April–May, specifically among Jews and others, with no corresponding increase among Arabs. Passover weeks were associated with a significantly higher risk of campylobacteriosis (incidence rate ratio (IRR) = 1.18; 95% CI: 1.12 to 1.23; p < 0.0001) compared with non-Passover weeks.
CONCLUSIONCampylobacteriosis incidence rate in Israel is high, particularly among young children. Collaboration between veterinary and public health authorities and timely public awareness campaigns, especially before holidays, are essential to reduce zoonotic transmission and prevent future peaks.
-
-
-
Rise in the number of notifications of Shiga toxin-producing Escherichia coli (STEC) infections probably linked to an increased use of multiplex PCR assays, Germany, 2023
More LessBACKGROUNDShiga toxin-producing Escherichia coli (STEC) can cause illnesses ranging from self-limiting diarrhoea to severe manifestations such as haemolytic-uraemic syndrome (HUS). In 2023, an increase in notified STEC cases was observed in the German federal state of Lower Saxony and nationwide.
AIMWe aimed to investigate possible reasons for the observed increase.
METHODSWe analysed data on notified STEC cases at federal and state level. All available STEC isolates from Lower Saxony from 2023 were whole genome sequenced. We sent a survey on detection and identification methods to 25 clinical microbiology laboratories in Lower Saxony.
RESULTSIn 2023, a statistically significant increase in notified STEC cases in all ages was seen in Lower Saxony and nationwide when compared with case numbers in 2022 and the median of 2015–2019 (p < 0.01). The highest increase was observed in people aged 60–69 years: 110 cases were notified in Lower Saxony in 2023 (median 2015–2019: 26) and 471 cases nationwide (median 2015–2019: 182). No overall increase was seen in disease severity or in the number of HUS cases. No larger genetic clusters or outbreaks were identified in Lower Saxony. The survey among the 17 responding laboratories in Lower Saxony revealed an increased use of multiplex PCR assays for gastrointestinal pathogens, introduced mainly in 2023.
CONCLUSIONThe increase in notified STEC cases was probably associated with the implementation of multiplex PCR assays for the analysis of gastrointestinal specimens. Our findings highlight the need to monitor diagnostic practices when assessing and evaluating surveillance data.
-
-
Volumes & issues
-
Volume 31 (2026)
-
Volume 30 (2025)
-
Volume 29 (2024)
-
Volume 28 (2023)
-
Volume 27 (2022)
-
Volume 26 (2021)
-
Volume 25 (2020)
-
Volume 24 (2019)
-
Volume 23 (2018)
-
Volume 22 (2017)
-
Volume 21 (2016)
-
Volume 20 (2015)
-
Volume 19 (2014)
-
Volume 18 (2013)
-
Volume 17 (2012)
-
Volume 16 (2011)
-
Volume 15 (2010)
-
Volume 14 (2009)
-
Volume 13 (2008)
-
Volume 12 (2007)
-
Volume 11 (2006)
-
Volume 10 (2005)
-
Volume 9 (2004)
-
Volume 8 (2003)
-
Volume 7 (2002)
-
Volume 6 (2001)
-
Volume 5 (2000)
-
Volume 4 (1999)
-
Volume 3 (1998)
-
Volume 2 (1997)
-
Volume 1 (1996)
-
Volume 0 (1995)
Most Read This Month
-
-
Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR
Victor M Corman , Olfert Landt , Marco Kaiser , Richard Molenkamp , Adam Meijer , Daniel KW Chu , Tobias Bleicker , Sebastian Brünink , Julia Schneider , Marie Luisa Schmidt , Daphne GJC Mulders , Bart L Haagmans , Bas van der Veer , Sharon van den Brink , Lisa Wijsman , Gabriel Goderski , Jean-Louis Romette , Joanna Ellis , Maria Zambon , Malik Peiris , Herman Goossens , Chantal Reusken , Marion PG Koopmans and Christian Drosten
-
- More Less
