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Abstract

An exponential growth model was fitted to critical care admissions from two surveillance databases to determine likely coronavirus disease (COVID-19) case numbers, critical care admissions and epidemic growth in the United Kingdom before the national lockdown. We estimate, on 23 March, a median of 114,000 (95% credible interval (CrI): 78,000–173,000) new cases and 258 (95% CrI: 220–319) new critical care reports, with 527,000 (95% CrI: 362,000–797,000) cumulative cases since 16 February.

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/content/10.2807/1560-7917.ES.2020.25.18.2000632
2020-05-07
2024-03-28
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2020.25.18.2000632
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References

  1. Public Health England (PHE). Coronavirus (COVID-19) in the UK. London: PHE. [Accessed: 3 Apr 2020]. Available from: https://coronavirus.data.gov.uk/downloads/csv/coronavirus-cases_latest.csv
  2. Mizumoto K, Kagaya K, Zarebski A, Chowell G. Estimating the asymptomatic proportion of coronavirus disease 2019 (COVID-19) cases on board the Diamond Princess cruise ship, Yokohama, Japan, 2020. Euro Surveill. 2020;25(10).  https://doi.org/10.2807/1560-7917.ES.2020.25.10.2000180  PMID: 32183930 
  3. Public Health England (PHE). COVID-19 guidance and microbiology: fourth update. HPR volume 14 issue 6 (24 and 25 March). [Accessed: 28 April 2020]. Available from: https://www.gov.uk/government/publications/health-protection-report-volume-14-2020/hpr-volume-14-issue-6-24-and-25-march
  4. Public Health England (PHE). COVID-19 Hospitalisation in England Surveillance System (CHESS) – daily reporting. [Accessed: 28 April 2020]. Available from: https://www.england.nhs.uk/coronavirus/wp-content/uploads/sites/52/2020/03/phe-letter-to-trusts-re-daily-covid-19-hospital-surveillance-11-march-2020.pdf
  5. Verity R, Okell LC, Dorigatti I, Winskill P, Whittaker C, Imai N, et al. Estimates of the severity of coronavirus disease 2019: a model-based analysis. Lancet Infect Dis. 2020;0:S1473-3099(20)30243-7.  https://doi.org/10.1016/S1473-3099(20)30243-7  PMID: 32240634 
  6. Bialek S, Boundy E, Bowen V, Chow N, Cohn A, Dowling N, et al. Severe outcomes among patients with coronavirus disease 2019 (COVID-19) - United States, February 12-March 16, 2020. MMWR Morb Mortal Wkly Rep. 2020;69(12):343-6.  https://doi.org/10.15585/mmwr.mm6912e2  PMID: 32214079 
  7. Riccardo F, Ajelli M, Andrianou X, Bella A, Manso M Del, Fabiani M, et al. Epidemiological characteristics of COVID-19 cases in Italy and estimates of the reproductive numbers one month into the epidemic. medRxiv. 2020;2020.04.08.20056861. doi: https://doi.org/10.1101/2020.04.08.20056861 .
  8. Nishiura H, Linton NM, Akhmetzhanov AR. Serial interval of novel coronavirus (COVID-19) infections. Int J Infect Dis. 2020;93:284-6.  https://doi.org/10.1016/j.ijid.2020.02.060  PMID: 32145466 
  9. Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054-62.  https://doi.org/10.1016/S0140-6736(20)30566-3  PMID: 32171076 
  10. Lourenco J, Paton R, Ghafari M, Kraemer M, Thompson C, Simmonds P, et al. Fundamental principles of epidemic spread highlight the immediate need for large-scale serological surveys to assess the stage of the SARS-CoV-2 epidemic. medRxiv. 2020;2020.03.24.20042291. doi: https://doi.org/10.1101/2020.03.24.20042291 .
  11. British Medical Association (BMA). COVID-19 – ethical issues. A guidance note. London: BMA; 2020. Available from: https://web.archive.org/web/20200426134240/https://www.bma.org.uk/media/2226/bma-covid-19-ethics-guidance.pdf
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