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Abstract

The SARS-CoV-2 Lambda (Pango lineage designation C.37) variant of interest, initially identified in Peru, has spread to additional countries. First detected in Israel in April 2021 following importations from Argentina and several European countries, the Lambda variant infected 18 individuals belonging to two main transmission chains without further spread. Micro-neutralisation assays following Comirnaty (BNT162b2 mRNA, BioNTech-Pfizer) vaccination demonstrated a significant 1.6-fold reduction in neutralising titres compared with the wild type virus, suggesting increased susceptibility of vaccinated individuals to infection.

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/content/10.2807/1560-7917.ES.2021.26.45.2100974
2021-11-11
2024-04-19
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.45.2100974
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The SARS-CoV-2 Lambda variant and its neutralisation efficiency following vaccination with Comirnaty, Israel, April to June 2021
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Neta+Zuckerman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Zuckerman Neta</a>, <a href="/search?value1=Ital+Nemet&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nemet Ital</a>, <a href="/search?value1=Limor+Kliker&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kliker Limor</a>, <a href="/search?value1=Nofar+Atari&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Atari Nofar</a>, <a href="/search?value1=Yaniv+Lustig&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lustig Yaniv</a>, <a href="/search?value1=Efrat+Bucris&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bucris Efrat</a>, <a href="/search?value1=Dana+Bar+Ilan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bar Ilan Dana</a>, <a href="/search?value1=Miranda+Geva&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Geva Miranda</a>, <a href="/search?value1=Reut+Sorek-Abramovich&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sorek-Abramovich Reut</a>, <a href="/search?value1=Chen+Weiner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Weiner Chen</a>, <a href="/search?value1=Nir+Rainy&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rainy Nir</a>, <a href="/search?value1=Adina+Bar-Chaim&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bar-Chaim Adina</a>, <a href="/search?value1=Patricia+Benveniste-Levkovitz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Benveniste-Levkovitz Patricia</a>, <a href="/search?value1=Ramzia+Abu+Hamed&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Abu Hamed Ramzia</a>, <a href="/search?value1=Gili+Regev-Yochay&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Regev-Yochay Gili</a>, <a href="/search?value1=Ofra+Hevkin&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hevkin Ofra</a>, <a href="/search?value1=Orna+Mor&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mor Orna</a>, <a href="/search?value1=Sharon+Alroy-Preis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alroy-Preis Sharon</a>, <a href="/search?value1=Ella+Mendelson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mendelson Ella</a>, <a href="/search?value1=Michal+Mandelboim&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mandelboim Michal</a></span>. The SARS-CoV-2 Lambda variant and its neutralisation efficiency following vaccination with Comirnaty, Israel, April to June 2021. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(45):pii=2100974. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.45.2100974" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.45.2100974</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 10 Oct 2021;&nbsp;&nbsp; <span class="generated">Accepted</span>: 11 Nov 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.45.2100974
/content/10.2807/1560-7917.ES.2021.26.45.2100974
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