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Eurosurveillance
Since 1995, Eurosurveillance has provided the European public health community with an open-access platform to exchange relevant findings on communicable disease surveillance, prevention and control. A weekly, electronic, peer-reviewed publication, Eurosurveillance aims to provide timely facts and guidance for public health professionals and decision-makers in the field of infectious disease to facilitate the implementation of effective prevention and control measures. Impact factor: 7.8. More...
Latest Issue: Volume 30, Issue 28, 17 July 2025 Latest Issue RSS feed
- Rapid communication
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Spread of the FAR-MRSA clone, a fusidic acid- and meticillin-resistant Staphylococcus aureus ST121, Europe, 2014 to 2024
Louise Roer , Nicolas Yin , Olivier Denis , Karuna EW Vendrik , Romy D Zwittink , Daan W Notermans , Monique Perrin , Kirstin Khonyongwa , Anne Tristan , Benjamin Youenou , Franziska Layer-Nicolaou , Guido Werner , Hege Enger , Emily Charlotte Henry Eikrem , Jessica Darenberg , Barbro Mäkitalo , Magnus Paulsson , Jonas Björkman , Hong Fang , Erika Tång Hallbäck , Martin Sundqvist , Laura Lindholm , Kartyk Moganeradj , Silvia García-Cobos , Javier E Cañada-García , Barbara Juliane Holzknecht , Helle Brander Eriksen , Morten Hoppe , Mette Damkjær Bartels , Jose Alfredo Samaniego Castruita , Tinna Ravnholt Urth , Anders Rhod Larsen and Andreas PetersenWe describe the genetic characteristics of a fusidic acid- and meticillin-resistant Staphylococcus aureus (MRSA) clone widespread in Europe, based on whole genome sequences from 317 isolates. The clone is causing impetigo and other skin and soft tissue infections, primarily in young children. Comparison with publicly available S. aureus ST121 sequences showed that the clone is clearly distinct from previously described ST121 clones. European and other international readers should be aware of the emergence of this community-acquired MRSA clone.
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Detection of West Nile virus via retrospective mosquito arbovirus surveillance, United Kingdom, 2025
Robert C Bruce , Anthony J Abbott , Ben P Jones , Bathsheba L Gardner , Estela Gonzalez , Andra-Maria Ionescu , Madhujot Jagdev , Ava Jenkins , Mariana Santos , Katharina Seilern-Macpherson , Hugh J Hanmer , Robert A Robinson , Alexander GC Vaux , Nicholas Johnson , Andrew A Cunningham , Becki Lawson , Jolyon M Medlock and Arran J FollyIn March 2025, as part of ongoing enhanced surveillance for mosquito-borne Orthoflaviviruses, West Nile virus (WNV) RNA was detected in two pools of female Aedes vexans collected in July 2023 in Nottinghamshire, England. Sequencing and phylogenetic analysis of a 402 bp fragment indicate clustering with WNV lineage 1a. The exact origin of this virus remains unclear, but this finding indicates a historic WNV presence in the United Kingdom. Surveillance has not provided evidence of further WNV transmission to date.
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- Research
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High-risk human papillomavirus cervical infection prevalence: a nationwide retrospective study comparing opportunistic and organised screening, France, 2020 to 2023
BACKGROUNDIn France, cervical cancer screening for females aged 30–65 years primarily tests for high-risk (HR) human papillomavirus (HPV) infections.
AIMWe aimed to map the prevalence of cervical infections caused by HPV16 and/or 18, or by any of 12 other carcinogenic HPV genotypes and compare prevalence estimates from tests from spontaneous medical visits (opportunistic screening) or the national screening programme (organised screening).
METHODSWe extracted data from a large network of biology laboratories, containing all available results from HR HPV tests performed between 1 January 2020 and 30 November 2023 in metropolitan France. A full hierarchical Bayesian model was used to compute spatially resolved expected prevalence maps at the postcode level.
RESULTSThe analytic sample contained results of 362,963 HR HPV tests. Among samples positive for HPV16 and/or 18, 2.9% and 3.8% were from organised and opportunistic screening, respectively. Samples positive for other genotypes were 6.9% and 9.4%, respectively.
During the last week of the study (week 48 2023), among females aged 30 years, opportunistic screening was associated with a greater expected prevalence of HPV16 and/or 18 and other genotypes in 97.2% and 99.9% of postcodes, respectively. The probability this percentage was lower among females aged 66 years was below 95% for both genotype groups.
For organised screening, a pronounced north-west/south-east gradient in infection prevalence was found across France for both genotype groups, with hotspots located at the border with Italy, Spain and Switzerland.
CONCLUSIONOpportunistic screening is associated with systematic inflation of HR HPV infection prevalence.
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Socioeconomic position and urban environments as drivers of antimicrobial resistance? An ecological study in Germany, 2010 to 2019
BACKGROUNDGermany lacks comprehensive studies on the relationship between socioeconomic position (SEP) and antimicrobial resistance (AMR).
AIMWe assessed the association between area-level SEP and AMR infection and colonisation in Germany.
METHODSIn an ecological study design, we analysed statutory notifications of invasive meticillin-resistant Staphylococcus aureus (MRSA, n = 34,440) in 2010−2019, and colonisations and infections with carbapenem-resistant Acinetobacter spp. (CRA, n = 1,979) and Enterobacterales (CRE, n = 10,825) in 2017−2019. Area-level SEP was measured by the German index of socioeconomic deprivation (GISD), incorporating education, employment and income data. A multilevel Poisson regression analysis estimated the association between AMR incidence and GISD at district level, adjusting for age, sex, notification year and urbanisation degree.
RESULTSMedian ages of patients with carbapenem-resistant bacteria were between 66 (CRA colonisation) and 69 years (CRE infection). For MRSA infections, the median age was 74 years. Across each pathogen, approximately two thirds of patients were male. Estimated MRSA incidence was almost five times higher in districts with lowest vs highest area-level SEP (incidence rate ratio, IRR: 4.8; 95% CI: 2.8–8.2). This association was strongest in large cities (IRR: 9.1; 95% CI: 2.7–30.9), and sparsely populated rural districts (IRR: 6.5; 95% CI: 2.8–15.0). Associations of CRA (IRR: 0.6; 95% CI: 0.3–1.2) and CRE (IRR: 0.9; 95% CI: 0.6–1.4) infections with SEP were not statistically significant.
CONCLUSIONLower area-level SEP and degree of urbanisation were associated with MRSA incidence, however, no associations were uncovered between SEP and CRA or CRE infections. Further individual-level research could explore if health behaviours, living/working conditions or healthcare access explain the findings. Socioeconomic conditions should be considered for AMR prevention and control.
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Recent articles
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Cross-border spread of a mosaic resistance (OXA-48) and virulence (aerobactin) plasmid in Klebsiella pneumoniae: a European Antimicrobial Resistance Genes Surveillance Network investigation, Europe, February 2019 to October 2024
Marius Linkevicius , Erik Alm , Louise Roer , Olov Svartström , Maria Dada-Olorunwa , Kati Räisänen , Felix Reichert , Sophie Möller , Christina Clarke , Martin Cormican , Baiba Niedre-Otomere , Reinis Vangravs , Paulius Greičius , Olga Burduniuc , Maria Anton , Antoni P.A. Hendrickx , Sandra Witteveen , Vilhelm Müller , Daniel Palm , Diamantis Plachouras , Dominique L. Monnet , Henrik Hasman and Anke Kohlenberg
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Surveillance of severe acute respiratory infections associated with SARS-CoV-2, influenza virus and RSV using ICD-10 codes: a case definition accuracy study across five European countries, 2021 to 2023
Miguel Angel Sanchez Ruiz , Diogo FP Marques , Frederikke Kristensen Lomholt , Lasse Skafte Vestergaard , Susana Monge , Marcos Lozano Álvarez , Gudrun Aspelund , Marianna Thordardottir , Ausra Dziugyte , John-Paul Cauchi , Tjarda M Boere , Irene K Veldhuijzen , Elina Seppälä , Håkon Bøås , Trine Hessevik Paulsen , ESURE SARI group , Ausenda Machado , Ana Paula Rodrigues , Mariette Hooiveld , Luis Alves de Sousa , Ana Torres , Carlos Carvalho and Baltazar Nunes
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