Vaccine effectiveness in preventing laboratory-confirmed influenza in Navarre, Spain: 2013/14 mid-season analysis

J Castilla; I Martínez-Baz; A Navascués; M Fernandez-Alonso; G Reina; M Guevara; J Chamorro; M T Ortega; E Albéniz; F Pozo; C Ezpeleta; Collective Primary Health Care Sentinel Network; Collective Network for Influenza Surveillance in Hospitals of Navarre

doi:10.2807/1560-7917.ES2014.19.6.20700

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Vaccine effectiveness in preventing laboratory-confirmed influenza in Navarre, Spain: 2013/14 mid-season analysis
J Castilla^1,2 , I Martínez-Baz^1,2 , A Navascués³ , M Fernandez-Alonso⁴ , G Reina⁴ , M Guevara^1,2 , J Chamorro³ , M T Ortega⁵ , E Albéniz⁶ , F Pozo⁷ , C Ezpeleta³ , Collective Primary Health Care Sentinel Network⁸ , Collective Network for Influenza Surveillance in Hospitals of Navarre⁸
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Affiliations: ¹ Instituto de Salud Pública de Navarra (Public Health Institute of Navarre), Pamplona, Spain ² Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP; Network of Biomedical Research Centers Epidemiology and Public Health), Spain ³ Complejo Hospitalario de Navarra (Hospital Complex of Navarre), Pamplona, Spain ⁴ Clínica Universidad de Navarra (University Clinic of Navarre), Pamplona, Spain ⁵ Hospital Reina Sofía, Tudela, Spain ⁶ Dirección de Atención Primaria (Primary Healthcare Directorate, Navarre Health Service), Pamplona, Spain ⁷ Centro Nacional de Microbiología (WHO National Influenza Centre - Madrid), Instituto de Salud Carlos III, Majadahonda, Spain ⁸ The members of these networks are listed at the end of the article

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J Castilla
jcastilc navarra.es
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Citation style for this article: Castilla J, Martínez-Baz I, Navascués A, Fernandez-Alonso M, Reina G, Guevara M, Chamorro J, Ortega M T, Albéniz E, Pozo F, Ezpeleta C, Primary Health Care Sentinel Network Collective, Network for Influenza Surveillance in Hospitals of Navarre Collective. Vaccine effectiveness in preventing laboratory-confirmed influenza in Navarre, Spain: 2013/14 mid-season analysis. Euro Surveill. 2014;19(6):pii=20700. https://doi.org/10.2807/1560-7917.ES2014.19.6.20700 Received: 31 Jan 2014

Abstract

We estimate mid-2013/14 season vaccine effectiveness (VE) of the influenza trivalent vaccine in Navarre, Spain. Influenza-like illness cases attended in hospital (n=431) and primary healthcare (n=344) were included. The overall adjusted VE in preventing laboratory-confirmed influenza was 24% (95% CI: ?14 to 50). The VE was 40% (95% CI: ?12 to 68) against influenza A(H1)pdm09 and 13% (95% CI: ?36 to 45) against influenza A(H3). These results suggest a moderate preventive effect against influenza A(H1)pdm09 and low protection against influenza A(H3).