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Note of concern published for 'Epidemiological investigation of MERS-CoV spread in a single hospital in South Korea, May to June 2015',

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Home Eurosurveillance Edition  2016: Volume 21/ Issue 4 Article 7
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Eurosurveillance, Volume 21, Issue 4, 28 January 2016
Weidmann: Addendum for Euro Surveill. 2015;20(44)

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Citation style for this article: Weidmann M. Addendum for Euro Surveill. 2015;20(44). Euro Surveill. 2016;21(4):pii=30121. DOI:

Received:28 January 2016; Accepted:28 January 2016

For the article ‘Development and deployment of a rapid recombinase polymerase amplification Ebola virus detection assay in Guinea in 2015’ (, by Faye et al., published on 05 November 2015, the authors would like to add that the World Health Organisation (WHO)-approved RealStar Filovirus Screen RT-PCR Kit 1.0 (Altona Diagnostics, Hamburg, Germany) has been widely used on Smart Cyclers throughout the Ebola outbreak in West Africa, although the manufacturer does not list this device in their instructions for use. The company published a note on its website on 10 July 2015 (, commenting the reported lack of sensitivity of this kit when used on a Smart Cycler. According to our findings, we consider that the reported lack of sensitivity is related to the restriction of using the kit for specific PCR cyclers only, as also found by other groups [1] previously.


  1. Janvier F, Sagui E, Foissaud V. ReEBOV Antigen Rapid Test kit for Ebola.Lancet. 2015;386(10010):2254-5. DOI: 10.1016/S0140-6736(15)01107-1 PMID: 26681288

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