Announcements
Eurosurveillance remains in the updated list of the Directory of Open Access Journals (DOAJ). It was first added to the DOAJ on 9 September 2004. Eurosurveillance is also listed in the Securing a Hybrid Environment for Research Preservation and Access / Rights MEtadata for Open archiving (SHERPA/RoMEO) [2], a database which uses a colour‐coding scheme to classify publishers according to their self‐archiving policy and to show the copyright and open access self-archiving policies of academic journals. Eurosurveillance is listed there as a ‘green’ journal, which means that authors can archive pre-print (i.e. pre-refereeing), post-print (i.e. final draft post-refereeing) and archive the publisher's version/PDF.

ESCAIDE participants are invited to the fifth Eurosurveillance scientific seminar on 30 November 2016

Follow Eurosurveillance on Twitter: @Eurosurveillanc

Read our articles on Zika virus infection

Read our articles on mcr-1-mediated colistin resistance

Note of concern published for 'Epidemiological investigation of MERS-CoV spread in a single hospital in South Korea, May to June 2015', http://bit.ly/29QFXPp


In this issue


Home Eurosurveillance Edition  2008: Volume 13/ Issue 8 Article 5
Back to Table of Contents
Previous Download (pdf)
Next

Eurosurveillance, Volume 13, Issue 8, 21 February 2008
News
Progressive inflammatory neuropathy (PIN) among swine slaughterhouse workers in Minnesota, United States, 2007-2008
  1. European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden

Citation style for this article: Eurosurveillance editorial team. Progressive inflammatory neuropathy (PIN) among swine slaughterhouse workers in Minnesota, United States, 2007-2008. Euro Surveill. 2008;13(8):pii=8047. Available online: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=8047

 

Between October 2007 and January 2008, 12 cases of a disease subsequently termed progressive inflammatory neuropathy (PIN) have been reported among workers in a swine slaughterhouse in Minnesota, United States. The onset of illness ranged from November 2006 through November 2007. The patients were between 21 and 51 years old, six were women.

Symptoms ranged from acute paralysis to gradually progressive symmetric weakness lasting from 8 to 213 days. Eleven patients had evidence of axonal or demyelinating peripheral neuropathy by electrodiagnostic testing. Cerebrospinal fluid obtained from seven patients showed elevated protein levels (median: 125 mg/dL; range: 75-231 mg/dL) with no or minimal pleocytosis (median: 1 cell/dL; range: 1-73 cells/dL in a nontraumatic tap). In five patients inflammation was shown on spinal magnetic resonance imaging.

The case-control study conducted in the course of the investigation indicated that the disease was associated with having worked at an area where swine heads were processed using a compressed-air device to extract pig brains. In the process of blowing compressed air into the pig skull, brain material might have been splattered or even aerosolized, and workers might have been exposed through inhalation or contact with mucous membranes. One hypothesis for development of PIN is that worker exposure to aerosolized pig neural protein might have induced an autoimmune-mediated peripheral neuropathy. Additional investigation of the characteristics and causes of PIN is under way.

To date no infectious agent has been identified, and the disease was not associated with travel; exposure to chemicals, fertilizers, or insecticides; use of medicines or vaccination. Pigs slaughtered at the plant have passed inspection by the food safety authorities and no food-borne risk to the general population was identified.

A review of 25 large pig slaughterhouses in the United States revealed that only three plants were using compressed-air devices for pig-brain extraction, and all have currently halted the use of this technique. To date there is no evidence of this practice being in use or cases of PIN occurring in Europe, but the relevant European Union bodies are aware of the event.

This article has been adapted from: Centers for Disease Control and Prevention (CDC). Investigation of progressive inflammatory neuropathy among swine slaughterhouse workers – Minnesota, 2007-2008. MMWR Morb Mortal Wkly Rep. 2008;57(5):122-4. Available from: http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5705a3.htm

 

 



Back to Table of Contents
Previous Download (pdf)
Next

The publisher’s policy on data collection and use of cookies.

Disclaimer: The opinions expressed by authors contributing to Eurosurveillance do not necessarily reflect the opinions of the European Centre for Disease Prevention and Control (ECDC) or the editorial team or the institutions with which the authors are affiliated. Neither ECDC nor any person acting on behalf of ECDC is responsible for the use that might be made of the information in this journal. The information provided on the Eurosurveillance site is designed to support, not replace, the relationship that exists between a patient/site visitor and his/her physician. Our website does not host any form of commercial advertisement. Except where otherwise stated, all manuscripts published after 1 January 2016 will be published under the Creative Commons Attribution (CC BY) licence. You are free to share and adapt the material, but you must give appropriate credit, provide a link to the licence, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.

Eurosurveillance [ISSN 1560-7917] - ©2007-2016. All rights reserved.
 

This website is certified by Health On the Net Foundation. Click to verify. This site complies with the HONcode standard for trustworthy health information:
verify here.