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Abstract

For over a decade virtually all A(H3N2) influenza viruses have been resistant to the adamantane class of antivirals. However, during the 2017 influenza season in Australia, 15/461 (3.3%) adamantane-sensitive A(H3N2) viruses encoding serine at residue 31 of the M2 protein were detected, more than the total number identified globally during the last 6 years. A return to wide circulation of adamantane-sensitive A(H3N2) viruses would revive the option of using these drugs for treatment and prophylaxis.

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/content/10.2807/1560-7917.ES.2017.22.47.17-00731
2017-11-23
2024-04-20
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2017.22.47.17-00731
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Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Aeron+Hurt&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hurt Aeron</a>, <a href="/search?value1=Naomi+Komadina&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Komadina Naomi</a>, <a href="/search?value1=Yi-Mo+Deng&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Deng Yi-Mo</a>, <a href="/search?value1=Matthew+Kaye&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kaye Matthew</a>, <a href="/search?value1=Sheena+Sullivan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sullivan Sheena</a>, <a href="/search?value1=Kanta+Subbarao&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Subbarao Kanta</a>, <a href="/search?value1=Ian+Barr&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Barr Ian</a></span>. Detection of adamantane-sensitive influenza A(H3N2) viruses in Australia, 2017: a cause for hope?. <a href="/content/ecdc">Euro Surveill.</a> 2017;22(47):pii=17-00731. <a href="https://doi.org/10.2807/1560-7917.ES.2017.22.47.17-00731" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2017.22.47.17-00731</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 03 Nov 2017;&nbsp;&nbsp; <span class="generated">Accepted</span>: 22 Nov 2017 </span> </p>
/content/10.2807/1560-7917.ES.2017.22.47.17-00731
/content/10.2807/1560-7917.ES.2017.22.47.17-00731
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