1887
  1. Home
  2. Eurosurveillance
  3. Volume 29, Issue 13, 28/Mar/2024
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

Group A isolates of the recently described M1 clade have emerged to cause human infections in several European countries and elsewhere. Full-genome sequence analysis of M1 isolates discovered a close genomic relationship between some isolates from Scotland and the majority of isolates from Iceland causing serious infections in 2022 and 2023. Phylogenetic analysis strongly suggests that an isolate from or related to Scotland was the precursor to an M1 variant responsible for almost all recent M1 infections in Iceland.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2024.29.13.2400129
2024-03-28
2024-04-27
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2024.29.13.2400129
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/29/13/eurosurv-29-13_2.html?itemId=/content/10.2807/1560-7917.ES.2024.29.13.2400129&mimeType=html&fmt=ahah

References

  1. Lynskey NN, Jauneikaite E, Li HK, Zhi X, Turner CE, Mosavie M, et al. Emergence of dominant toxigenic M1T1 Streptococcus pyogenes clone during increased scarlet fever activity in England: a population-based molecular epidemiological study. Lancet Infect Dis. 2019;19(11):1209-18.  https://doi.org/10.1016/S1473-3099(19)30446-3  PMID: 31519541 
  2. Davies MR, Keller N, Brouwer S, Jespersen MG, Cork AJ, Hayes AJ, et al. Detection of Streptococcus pyogenes M1UK in Australia and characterization of the mutation driving enhanced expression of superantigen SpeA. Nat Commun. 2023;14(1):1051.  https://doi.org/10.1038/s41467-023-36717-4  PMID: 36828918 
  3. Li HK, Zhi X, Vieira A, Whitwell HJ, Schricker A, Jauneikaite E, et al. Characterization of emergent toxigenic M1UK Streptococcus pyogenes and associated sublineages. Microb Genom. 2023;9(4):mgen000994.  https://doi.org/10.1099/mgen.0.000994  PMID: 37093716 
  4. Aboulhosn A, Sanson MA, Vega LA, Segura MG, Summer LM, Joseph M, et al. Increases in group A streptococcal infections in the pediatric population in Houston, TX, 2022. Clin Infect Dis. 2023;77(3):351-4.  https://doi.org/10.1093/cid/ciad197  PMID: 37011014 
  5. Butler TAJ, Story C, Green E, Williamson KM, Newton P, Jenkins F, et al. Insights gained from sequencing Australian non-invasive and invasive Streptococcus pyogenes isolates. Microb Genom. 2024;10(1):001152.  https://doi.org/10.1099/mgen.0.001152  PMID: 38197886 
  6. Davies PJB, Russell CD, Morgan AR, Taori SK, Lindsay D, Ure R, et al. Increase of severe pulmonary infections in adults caused by M1UK Streptococcus pyogenes, central Scotland, UK. Emerg Infect Dis. 2023;29(8):1638-42.  https://doi.org/10.3201/eid2908.230569  PMID: 37343545 
  7. de Gier B, Marchal N, de Beer-Schuurman I, Te Wierik M, Hooiveld M, de Melker HE, et al. Increase in invasive group A streptococcal (Streptococcus pyogenes) infections (iGAS) in young children in the Netherlands, 2022. Euro Surveill. 2023;28(1):2200941.  https://doi.org/10.2807/1560-7917.ES.2023.28.1.2200941  PMID: 36695447 
  8. Demczuk W, Martin I, Domingo FR, MacDonald D, Mulvey MR. Identification of Streptococcus pyogenes M1UK clone in Canada. Lancet Infect Dis. 2019;19(12):1284-5.  https://doi.org/10.1016/S1473-3099(19)30622-X  PMID: 31782392 
  9. Gouveia C, Bajanca-Lavado MP, Mamede R, Araújo Carvalho A, Rodrigues F, Melo-Cristino J, et al. Sustained increase of paediatric invasive Streptococcus pyogenes infections dominated by M1UK and diverse emm12 isolates, Portugal, September 2022 to May 2023. Euro Surveill. 2023;28(36):2300427.  https://doi.org/10.2807/1560-7917.ES.2023.28.36.2300427  PMID: 37676143 
  10. Johannesen TB, Munkstrup C, Edslev SM, Baig S, Nielsen S, Funk T, et al. Increase in invasive group A streptococcal infections and emergence of novel, rapidly expanding sub-lineage of the virulent Streptococcus pyogenes M1 clone, Denmark, 2023. Euro Surveill. 2023;28(26):2300291.  https://doi.org/10.2807/1560-7917.ES.2023.28.26.2300291  PMID: 37382884 
  11. Lacey JA, Bennett J, James TB, Hines BS, Chen T, Lee D, et al. A worldwide population of Streptococcus pyogenes strains circulating among school-aged children in Auckland, New Zealand: a genomic epidemiology analysis. Lancet Reg Health West Pac. 2024;42:100964.  https://doi.org/10.1016/j.lanwpc.2023.100964  PMID: 38035130 
  12. Li Y, Nanduri SA, Van Beneden CA, Beall BW. M1UK lineage in invasive group A streptococcus isolates from the USA. Lancet Infect Dis. 2020;20(5):538-9.  https://doi.org/10.1016/S1473-3099(20)30279-6  PMID: 32359463 
  13. Rodriguez-Ruiz JP, Lin Q, Lammens C, Smeesters PR, van Kleef-van Koeveringe S, Matheeussen V, et al. Increase in bloodstream infections caused by emm1 group A Streptococcus correlates with emergence of toxigenic M1UK, Belgium, May 2022 to August 2023. Euro Surveill. 2023;28(36):2300422.  https://doi.org/10.2807/1560-7917.ES.2023.28.36.2300422  PMID: 37676145 
  14. Wolters M, Berinson B, Degel-Brossmann N, Hoffmann A, Bluszis R, Aepfelbacher M, et al. Population of invasive group A streptococci isolates from a German tertiary care center is dominated by the hypertoxigenic virulent M1UK genotype. Infection. 2023. PMID: 38064158 
  15. Holdstock V, Twynam-Perkins J, Bradnock T, Dickson EM, Harvey-Wood K, Kalima P, et al. National case series of group A streptococcus pleural empyema in children: clinical and microbiological features. Lancet Infect Dis. 2023;23(2):154-6.  https://doi.org/10.1016/S1473-3099(23)00008-7  PMID: 36634683 
  16. Beres SB, Olsen RJ, Long SW, Eraso JM, Boukthir S, Faili A, et al. Analysis of the genomics and mouse virulence of an emergent clone of Streptococcus dysgalactiae Subspecies equisimilis. Microbiol Spectr. 2023;11(2):e0455022.  https://doi.org/10.1128/spectrum.04550-22  PMID: 36971562 
  17. Hoe N, Nakashima K, Grigsby D, Pan X, Dou SJ, Naidich S, et al. Rapid molecular genetic subtyping of serotype M1 group A Streptococcus strains. Emerg Infect Dis. 1999;5(2):254-63.  https://doi.org/10.3201/eid0502.990210  PMID: 10221878 
  18. Hoe NP, Nakashima K, Lukomski S, Grigsby D, Liu M, Kordari P, et al. Rapid selection of complement-inhibiting protein variants in group A Streptococcus epidemic waves. Nat Med. 1999;5(8):924-9.  https://doi.org/10.1038/11369  PMID: 10426317 
  19. Hoe NP, Kordari P, Cole R, Liu M, Palzkill T, Huang W, et al. Human immune response to streptococcal inhibitor of complement, a serotype M1 group A Streptococcus extracellular protein involved in epidemics. J Infect Dis. 2000;182(5):1425-36.  https://doi.org/10.1086/315882  PMID: 11015234 
  20. Hoe NP, Vuopio-Varkila J, Vaara M, Grigsby D, De Lorenzo D, Fu YX, et al. Distribution of streptococcal inhibitor of complement variants in pharyngitis and invasive isolates in an epidemic of serotype M1 group A Streptococcus infection. J Infect Dis. 2001;183(4):633-9.  https://doi.org/10.1086/318543  PMID: 11170990 
  21. Matsumoto M, Hoe NP, Liu M, Beres SB, Sylva GL, Brandt CM, et al. Intrahost sequence variation in the streptococcal inhibitor of complement gene in patients with human pharyngitis. J Infect Dis. 2003;187(4):604-12.  https://doi.org/10.1086/367993  PMID: 12599077 
  22. Stockbauer KE, Grigsby D, Pan X, Fu YX, Mejia LM, Cravioto A, et al. Hypervariability generated by natural selection in an extracellular complement-inhibiting protein of serotype M1 strains of group A Streptococcus. Proc Natl Acad Sci USA. 1998;95(6):3128-33.  https://doi.org/10.1073/pnas.95.6.3128  PMID: 9501227 
  23. Icelandic Tourist Board. Tourism in Iceland in Figures, January 2023: Summary for the year 2022. 2023. Reykjavík: Ferðamálastofa; 2023. Available from: https://www.ferdamalastofa.is/en/moya/news/tourism-in-figures-january-2023
  24. Nasser W, Beres SB, Olsen RJ, Dean MA, Rice KA, Long SW, et al. Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences. Proc Natl Acad Sci USA. 2014;111(17):E1768-76.  https://doi.org/10.1073/pnas.1403138111  PMID: 24733896 
Increase in invasive Streptococcus pyogenes M1 infections with close evolutionary genetic relationship, Iceland and Scotland, 2022 to 2023
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Stephen+B+Beres&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Beres Stephen B</a>, <a href="/search?value1=Randall+J+Olsen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Olsen Randall J</a>, <a href="/search?value1=S+Wesley+Long&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Long S Wesley</a>, <a href="/search?value1=Ross+Langley&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Langley Ross</a>, <a href="/search?value1=Thomas+Williams&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Williams Thomas</a>, <a href="/search?value1=Helga+Erlendsdottir&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Erlendsdottir Helga</a>, <a href="/search?value1=Andrew+Smith&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Smith Andrew</a>, <a href="/search?value1=Karl+G+Kristinsson&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kristinsson Karl G</a>, <a href="/search?value1=James+M+Musser&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Musser James M</a></span>. Increase in invasive Streptococcus pyogenes M1 infections with close evolutionary genetic relationship, Iceland and Scotland, 2022 to 2023. <a href="/content/ecdc">Euro Surveill.</a> 2024;29(13):pii=2400129. <a href="https://doi.org/10.2807/1560-7917.ES.2024.29.13.2400129" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2024.29.13.2400129</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 26 Feb 2024;&nbsp;&nbsp; <span class="generated">Accepted</span>: 27 Mar 2024 </span> </p>
/content/10.2807/1560-7917.ES.2024.29.13.2400129
/content/10.2807/1560-7917.ES.2024.29.13.2400129
Loading

Data & Media loading...

Supplementary data

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error