1887
Rapid communication Open Access
Like 0
This item has no PDF Download

Abstract

We describe a case of severe swine influenza A(H1N1) virus infection in an immunocompetent middle-aged man in October 2016 in Italy who had only indirect exposure to pigs. The patient developed a severe acute distress respiratory syndrome which was successfully supported by extracorporeal membrane oxygenation and treated with antiviral therapy. The sole risk factor for influenza was a body mass index > 30 kg/m2. After a month of hospitalisation, the patient was discharged in good health.

Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2017.22.5.30456
2017-02-02
2017-10-19
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2017.22.5.30456
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/22/5/eurosurv-22-30456-3.html?itemId=/content/10.2807/1560-7917.ES.2017.22.5.30456&mimeType=html&fmt=ahah

References

  1. Piralla A, Baldanti F, Gerna G. Phylogenetic patterns of human respiratory picornavirus species, including the newly identified group C rhinoviruses, during a 1-year surveillance of a hospitalized patient population in Italy. J Clin Microbiol. 2011;49(1):373-6.  https://doi.org/10.1128/JCM.01814-10  PMID: 21068279 
  2. World Health Organization (WHO). CDC protocol of realtime RTPCR for influenza A(H1N1). Geneva: WHO; 2009. [Accessed: 15 Dec 2009]. Available from: http://www.who.int/csr/resources/publications/swineflu/CDCRealtimeRTPCR_SwineH1Assay-2009_20090430.pdf
  3. Hoffmann E, Stech J, Guan Y, Webster RG, Perez DR. Universal primer set for the full-length amplification of all influenza A viruses. Arch Virol. 2001;146(12):2275-89.  https://doi.org/10.1007/s007050170002  PMID: 11811679 
  4. Lycett SJ, Baillie G, Coulter E, Bhatt S, Kellam P, McCauley JW, et al. Estimating reassortment rates in co-circulating Eurasian swine influenza viruses. J Gen Virol. 2012;93(Pt 11):2326-36.  https://doi.org/10.1099/vir.0.044503-0  PMID: 22971819 
  5. Tamura K, Stecher G, Peterson D, Filipski A, Kumar S. MEGA6: Molecular Evolutionary Genetics Analysis version 6.0. Mol Biol Evol. 2013;30(12):2725-9.  https://doi.org/10.1093/molbev/mst197  PMID: 24132122 
  6. Fraaij PL, Wildschut ED, Houmes RJ, Swaan CM, Hoebe CJ, de Jonge HC, et al. Severe acute respiratory infection caused by swine influenza virus in a child necessitating extracorporeal membrane oxygenation (ECMO), the Netherlands, October 2016. Euro Surveill. 2016;21(48):30416.  https://doi.org/10.2807/1560-7917.ES.2016.21.48.30416  PMID: 27934581 
  7. World Organisation for Animal Health OIE). Manual of diagnostic tests and vaccines for terrestrial animals. Chapter 2.8.7. Influenza A virus of swine. Paris: OIE. [Accessed: 6 Jun 2014]. Available from: http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/2.08.07_INF_A_SWINE.pdf
  8. Myers KP, Olsen CW, Gray GC. Cases of swine influenza in humans: a review of the literature. Clin Infect Dis. 2007;44(8):1084-8.  https://doi.org/10.1086/512813  PMID: 17366454 
  9. Krueger WS, Gray GC. Swine influenza virus infections in man. Curr Top Microbiol Immunol. 2013;370:201-25.  https://doi.org/10.1007/82_2012_268  PMID: 23023606 
  10. Krumbholz A, Lange J, Dürrwald R, Walther M, Müller TH, Kühnel D, et al. Prevalence of antibodies to European porcine influenza viruses in humans living in high pig density areas of Germany. Med Microbiol Immunol (Berl). 2014;203(1):13-24.  https://doi.org/10.1007/s00430-013-0309-y  PMID: 24013183 
  11. Piralla A, Moreno A, Orlandi ME, Percivalle E, Chiapponi C, Vezzoli F, et al. Swine influenza A(H3N2) virus infection in immunocompetent man, Italy, 2014. Emerg Infect Dis. 2015;21(7):1189-91.  https://doi.org/10.3201/eid2107.140981  PMID: 26079745 
  12. Watson SJ, Langat P, Reid SM, Lam TT, Cotten M, Kelly M, et al. Molecular epidemiology and evolution of influenza viruses circulating within European swine between 2009 and 2013. J Virol. 2015;89(19):9920-31.  https://doi.org/10.1128/JVI.00840-15  PMID: 26202246 
/content/10.2807/1560-7917.ES.2017.22.5.30456
Loading

Data & Media loading...

Comment has been disabled for this content
Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error