Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015

Alexis Pillsbury; Patrick Cashman; Alan Leeb; Annette Regan; Darren Westphal; Tom Snelling; Christopher Blyth; Nigel Crawford; Nicholas Wood; Kristine Macartney; on behalf of the AusVaxSafety

doi:10.2807/1560-7917.ES.2015.20.43.30050

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Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015
Alexis Pillsbury¹ , Patrick Cashman^2,3 , Alan Leeb⁴ , Annette Regan^5,6 , Darren Westphal^5,7,8 , Tom Snelling^7,9 , Christopher Blyth^7,9,10 , Nigel Crawford^11,12,13 , Nicholas Wood^1,14 , Kristine Macartney^1,2,15 , on behalf of the AusVaxSafety ¹⁶
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Affiliations: ¹ National Centre for Immunisation Research and Surveillance, The Children’s Hospital at Westmead, NSW, Australia ² Hunter New England Local Health District, NSW, Australia ³ The University of Newcastle, NSW, Australia ⁴ Illawarra Medical Centre, WA, Australia ⁵ Communicable Disease Control Directorate, Western Australia Department of Health, WA, Australia ⁶ School of Pathology and Laboratory Medicine, University of Western Australia, WA, Australia ⁷ Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, WA, Australia ⁸ National Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University, ACT, Australia ⁹ Princess Margaret Hospital, WA, Australia ¹⁰ University of Western Australia School of Paediatrics and Child Health, Princess Margaret Hospital, WA, Australia ¹¹ Department of General Medicine, Royal Children's Hospital, Victoria, Australia ¹² SAEFVIC, Murdoch Childrens Research Institute, Victoria, Australia ¹³ Department of Paediatrics, The University of Melbourne, Victoria, Australia ¹⁴ Discipline of Paediatrics and Child Health, University of Sydney, NSW, Australia ¹⁵ Department of Microbiology and Infectious Diseases, The Children’s Hospital at Westmead, NSW, Australia ¹⁶ The members of the group are listed at the end of the article.

Correspondence:
Alexis Pillsbury
alexis.pillsbury health.nsw.gov.au
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Citation style for this article: Pillsbury Alexis, Cashman Patrick, Leeb Alan, Regan Annette, Westphal Darren, Snelling Tom, Blyth Christopher, Crawford Nigel, Wood Nicholas, Macartney Kristine, on behalf of the AusVaxSafety . Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015. Euro Surveill. 2015;20(43):pii=30050. https://doi.org/10.2807/1560-7917.ES.2015.20.43.30050 Received: 14 Oct 2015; Accepted: 29 Oct 2015

Abstract

Increased febrile reactions in Australian children from one influenza vaccine brand in 2010 diminished confidence in influenza immunisation, highlighting the need for improved vaccine safety surveillance. AusVaxSafety, a national vaccine safety surveillance system collected adverse events in young children for 2015 influenza vaccine brands in real time through parent/carer reports via SMS/email. Weekly cumulative data on 3,340 children demonstrated low rates of fever (4.4%) and medical attendance (1.1%). Fever was more frequent with concomitant vaccination.

This work is licensed under a Creative Commons Attribution 4.0 International License.

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Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015

Citation style for this article: <a href="/search?value1=Alexis+Pillsbury&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pillsbury Alexis</a>, <a href="/search?value1=Patrick+Cashman&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Cashman Patrick</a>, <a href="/search?value1=Alan+Leeb&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Leeb Alan</a>, <a href="/search?value1=Annette+Regan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Regan Annette</a>, <a href="/search?value1=Darren+Westphal&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Westphal Darren</a>, <a href="/search?value1=Tom+Snelling&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Snelling Tom</a>, <a href="/search?value1=Christopher+Blyth&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Blyth Christopher</a>, <a href="/search?value1=Nigel+Crawford&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Crawford Nigel</a>, <a href="/search?value1=Nicholas+Wood&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wood Nicholas</a>, <a href="/search?value1=Kristine+Macartney&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Macartney Kristine</a>, <a href="/search?value1=on+behalf+of+the+AusVaxSafety&option1=author&noRedirect=true" class="nonDisambigAuthorLink">on behalf of the AusVaxSafety </a>. Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015. <a href="/content/ecdc">Euro Surveill.</a> 2015;20(43):pii=30050. <a href="https://doi.org/10.2807/1560-7917.ES.2015.20.43.30050" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2015.20.43.30050</a> Received: 14 Oct 2015;   Accepted: 29 Oct 2015

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Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015

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