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Carbapenemase-producing Enterobacteriaceae in Europe: assessment by national experts from 38 countries, May 2015
- Barbara Albiger1 , Corinna Glasner2,3 , Marc J. Struelens1 , Hajo Grundmann2 , Dominique L. Monnet1 , the European Survey of Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) working group4
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View Affiliations Hide AffiliationsAffiliations: 1 European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden 2 Department of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands 3 Current affiliation: The Centre for Genomic Pathogen Surveillance (cGPS), Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom 4 The members of the European Survey of Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) working group are listed at the end of the articleBarbara Albigerbarbara.albiger ecdc.europa.eu
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Citation style for this article: Albiger Barbara, Glasner Corinna, Struelens Marc J., Grundmann Hajo, Monnet Dominique L., the European Survey of Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) working group. Carbapenemase-producing Enterobacteriaceae in Europe: assessment by national experts from 38 countries, May 2015. Euro Surveill. 2015;20(45):pii=30062. https://doi.org/10.2807/1560-7917.ES.2015.20.45.30062 Received: 01 Oct 2015; Accepted: 06 Nov 2015
Abstract
In 2012, the European Centre for Disease Prevention and Control (ECDC) launched the ‘European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE)’ project to gain insights into the occurrence and epidemiology of carbapenemase-producing Enterobacteriaceae (CPE), to increase the awareness of the spread of CPE, and to build and enhance the laboratory capacity for diagnosis and surveillance of CPE in Europe. Data collected through a post-EuSCAPE feedback questionnaire in May 2015 documented improvement compared with 2013 in capacity and ability to detect CPE and identify the different carbapenemases genes in the 38 participating countries, thus contributing to their awareness of and knowledge about the spread of CPE. Over the last two years, the epidemiological situation of CPE worsened, in particular with the rapid spread of carbapenem-hydrolysing oxacillinase-48 (OXA-48)- and New Delhi metallo-beta-lactamase (NDM)-producing Enterobacteriaceae. In 2015, 13/38 countries reported inter-regional spread of or an endemic situation for CPE, compared with 6/38 in 2013. Only three countries replied that they had not identified one single case of CPE. The ongoing spread of CPE represents an increasing threat to patient safety in European hospitals, and a majority of countries reacted by establishing national CPE surveillances systems and issuing guidance on control measures for health professionals. However, 14 countries still lacked specific national guidelines for prevention and control of CPE in mid-2015.
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