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Abstract

In 2013, 15 clusters of mumps were notified in France; 72% (82/114) of the cases had been vaccinated twice with measles-mumps-rubella vaccine. To determine whether the risk of mumps increased with time since the last vaccination, we conducted a case–control study among clusters in universities and military barracks. A confirmed case had an inflammation of a salivary gland plus laboratory confirmation in 2013. A probable case presented with inflammation of a salivary gland in 2013 either lasting for > 2 days or with epidemiological link to a confirmed case. Controls had no mumps symptoms and attended the same university course, student party or military barracks. We collected clinical and vaccination data via web questionnaire and medical records. We calculated adjusted odds ratios (aOR) using logistic regression. 59% (50/85) of cases and 62% (199/321) of controls had been vaccinated twice. The odds of mumps increased for twice-vaccinated individuals by 10% for every year that had passed since the second dose (aOR 1.10; 95% confidence interval (CI): 1.02–1.19; p = 0.02). Mumps immunity waned with increasing time since vaccination. Our findings contributed to the French High Council of Public Health’s decision to recommend a third MMR dose during outbreaks for individuals whose second dose dates > 10 years.

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/content/10.2807/1560-7917.ES.2016.21.10.30156
2016-03-10
2021-02-24
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2016.21.10.30156
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References

  1. Institut de Veille Sanitaire (InVS). Dossiers thématiques; Oreillons. [Thematic dossiers; mumps]. French. [Accessed 15 Jul 2013]. Available from: http://www.invs.sante.fr/Dossiers-thematiques/Maladies-infectieuses/Maladies-a-prevention-vaccinale/Oreillons
  2. Coffinières E, Turbelin C, Riblier D, Aouba A, Levy-Bruhl D, Arena C, et al. Mumps: burden of disease in France. Vaccine. 2012;30(49):7013-8.  https://doi.org/10.1016/j.vaccine.2012.09.070  PMID: 23059354 
  3. Nelson GE, Aguon A, Valencia E, Oliva R, Guerrero ML, Reyes R, et al. Epidemiology of a mumps outbreak in a highly vaccinated island population and use of a third dose of measles-mumps-rubella vaccine for outbreak control--Guam 2009 to 2010. Pediatr Infect Dis J. 2013;32(4):374-80.  https://doi.org/10.1097/INF.0b013e318279f593  PMID: 23099425 
  4. Institut national de prévention et d'éducation pour la santé (Inpes), Paris, France. Vaccination contre les oreillons, dans Guide des vaccinations - Edition 2012, page 223-229. [Vaccination against mumps, in the guide to vaccinations – edition 2012, pp. 142-8]. Paris: Inpes; 2012. French. Available from: http://www.inpes.sante.fr/10000/themes/vaccination/guide-vaccination-2012/pdf/GuideVaccinations2012_Vaccination_contre_les_oreillons.pdf
  5. Le calendrier des vaccinations et les recommandations vaccinales 1996-1997. [Vaccination calendar and vaccination recommendations 1996-1997]. Bull Epidemiol Hebd. 1996; 35: 151-3. French. Available from: http://www.invs.sante.fr/beh/1996/9635/index.html
  6. Institut de Veille Sanitaire. Comité technique des vaccinations, Paris, France. Calendrier des vaccinations et les recommandations vaccinales 2013 selon l'avis du Haut conseil de la santé publique. [Vaccination calendar and vaccination recommendations for 2013 according to the opinion of the High council of public health]. Bull Epidemiol Hebd 2013;14-15. French. Available from: http://www.invs.sante.fr/Publications-et-outils/BEH-Bulletin-epidemiologique-hebdomadaire/Archives/2013/BEH-n-14-15-2013
  7. Antona D, Fonteneau L, Lévy-Bruhl D, Guignon N, De Peretti C, Niel X, et al. Couverture vaccinale des enfants et des adolescents en France: résultats des enquêtes menées en milieu scolaire, 2001-2004. [Vaccination coverage of children and adolescents in France: results of a school survey, 2001-2014]. Bull Epidemiol Hebd 2007;6:45-9. French. Available from: http://www.invs.sante.fr/beh/2007/06/beh_06_2007.pdf
  8. The French National Institute of Health and Medical Research (Inserm U707). University of Paris VI: Pierre and Marie Curie, Paris, France. Réseau Sentinelles [French GP sentinel network]. French. [Accessed in June 2013]. Available from: http://websenti.u707.jussieu.fr/sentiweb/?page=bilan
  9. Sane J, Gouma S, Koopmans M, de Melker H, Swaan C, van Binnendijk R, et al. Epidemic of mumps among vaccinated persons, The Netherlands, 2009-2012. Emerg Infect Dis. 2014;20(4):643-8.  https://doi.org/10.3201/eid2004.131681  PMID: 24655811 
  10. Dayan GH, Quinlisk MP, Parker AA, Barskey AE, Harris ML, Schwartz JM, et al. Recent resurgence of mumps in the United States. N Engl J Med. 2008;358(15):1580-9.  https://doi.org/10.1056/NEJMoa0706589  PMID: 18403766 
  11. Eriksen J, Davidkin I, Kafatos G, Andrews N, Barbara C, Cohen D, et al. Seroepidemiology of mumps in Europe (1996-2008): why do outbreaks occur in highly vaccinated populations? Epidemiol Infect. 2013;141(3):651-66.  https://doi.org/10.1017/S0950268812001136  PMID: 22687578 
  12. Anis E, Grotto I, Moerman L, Warshavsky B, Slater PE, Lev B. Mumps outbreak in Israel’s highly vaccinated society: are two doses enough? Epidemiol Infect. 2012;140(3):439-46.  https://doi.org/10.1017/S095026881100063X  PMID: 21554780 
  13. Dayan GH, Rubin S. Mumps outbreaks in vaccinated populations: are available mumps vaccines effective enough to prevent outbreaks? Clin Infect Dis. 2008;47(11):1458-67.  https://doi.org/10.1086/591196  PMID: 18959494 
  14. Yung CF, Andrews N, Bukasa A, Brown KE, Ramsay M. Mumps complications and effects of mumps vaccination, England and Wales, 2002-2006. Emerg Infect Dis. 2011;17(4):661-7, quiz 766.  https://doi.org/10.3201/eid1704.101461  PMID: 21470456 
  15. Cohen C, White JM, Savage EJ, Glynn JR, Choi Y, Andrews N, et al. Vaccine effectiveness estimates, 2004-2005 mumps outbreak, England. Emerg Infect Dis. 2007;13(1):12-7.  https://doi.org/10.3201/eid1301.060649  PMID: 17370510 
  16. Marin M, Quinlisk P, Shimabukuro T, Sawhney C, Brown C, Lebaron CW. Mumps vaccination coverage and vaccine effectiveness in a large outbreak among college students--Iowa, 2006. Vaccine. 2008;26(29-30):3601-7.  https://doi.org/10.1016/j.vaccine.2008.04.075  PMID: 18539365 
  17. Haut Conseil de la santé publique (HCSP). Avis relatif à la conduite à tenir en case d’épisodes de cas groupés d’oreillons en collectivité. Paris : HCSP; 11 Jul 2013. [Opinion on the conduct to adopt in the face of episodes of clusters of mumps in institutions]. French. Available from: http://www.hcsp.fr/Explore.cgi/avisrapportsdomaine?clefr=364
  18. Gee S, O’Flanagan D, Fitzgerald M, Cotter S. Mumps in Ireland, 2004-2008. Euro Surveill. 2008;13(18):18857. Available from: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=18857 PMID: 18768133 
  19. Ogbuanu IU, Kutty PK, Hudson JM, Blog D, Abedi GR, Goodell S, et al. Impact of a third dose of measles-mumps-rubella vaccine on a mumps outbreak. Pediatrics. 2012 Dec;130(6):e1567-74. Available from: http://pediatrics.aappublications.org/content/130/6/e1567.full.pdf
  20. Rajčević S, Šeguljev Z, Petrovic V, Medić S, Nedelijković J, Milosević V, et al. Ongoing mumps outbreak in Novi Sad, the autonomous province of Vojvodina, Serbia, January to April 2012. Euro Surveill. 2012;17(19):20169. PMID: 22607963 
  21. Quinlisk MP. Mumps control today. J Infect Dis. 2010;202(5):655-6.  https://doi.org/10.1086/655395  PMID: 20662719 
  22. Cortese MM, Jordan HT, Curns AT, Quinlan PA, Ens KA, Denning PM, et al. Mumps vaccine performance among university students during a mumps outbreak. Clin Infect Dis. 2008;46(8):1172-80.  https://doi.org/10.1086/529141  PMID: 18444852 
  23. Gouma S, Sane J, Gijselaar D, Cremer J, Hahné S, Koopmans M, et al. Two major mumps genotype G variants dominated recent mumps outbreaks in the Netherlands (2009-2012). J Gen Virol. 2014;95(Pt 5):1074-82.  https://doi.org/10.1099/vir.0.062943-0  PMID: 24603524 
  24. Savage E, Ramsay M, White J, Beard S, Lawson H, Hunjan R, et al. Mumps outbreaks across England and Wales in 2004: observational study. BMJ. 2005;330(7500):1119-20.  https://doi.org/10.1136/bmj.330.7500.1119  PMID: 15891227 
  25. Hahné S, Whelan J, van Binnendijk R, Swaan C, Fanoy E, Boot H, et al. Mumps vaccine effectiveness against orchitis. Emerg Infect Dis. 2012;18(1):191-3.  https://doi.org/10.3201/eid1801.111178  PMID: 22260843 
  26. Ladbury G, Ostendorf S, Waegemaekers T, van Binnendijk R, Boot H, Hahné S. Smoking and older age associated with mumps in an outbreak in a group of highly-vaccinated individuals attending a youth club party, the Netherlands, 2012. Euro Surveill. 2014;19(16):20776. . Available from: http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=20776 https://doi.org/10.2807/1560-7917.ES2014.19.16.20776  PMID: 24786261 
  27. De Serres G, Boulianne N, Defay F, Brousseau N, Benoît M, Lacoursière S, et al. Higher risk of measles when the first dose of a 2-dose schedule is given at 12-14 versus 15 months of age. Clin Infect Dis. 2012;55(3):394-402.  https://doi.org/10.1093/cid/cis439  PMID: 22543023 
  28. Hall R, Richards H. Hearing loss due to mumps. Arch Dis Child. 1987;62(2):189-91.  https://doi.org/10.1136/adc.62.2.189  PMID: 3827297 
  29. Gupta RK, Best J, MacMahon E. Mumps and the UK epidemic 2005. BMJ. 2005;330(7500):1132-5. . Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC557899/ https://doi.org/10.1136/bmj.330.7500.1132  PMID: 15891229 
  30. Arday DR, Kanjarpane DD, Kelley PW. Mumps in the US Army 1980-86: should recruits be immunized? Am J Public Health. 1989;79(4):471-4.  https://doi.org/10.2105/AJPH.79.4.471  PMID: 2494895 
  31. Rubin SA, Plotkin SA. Mumps vaccine. In: Plotkin S, Orenstein W, Offit P, editors. Vaccines. 6th ed. Philadelphia: Saunders; 2012. p. 419-46.
  32. Levine H, Rishpon S, Huerta-Hartal M, Davidovitch N. Preventing mumps outbreaks in confined settings: comprehensive ring vaccination as a containment strategy. Hum Vaccin. 2011;7(12):1389-93. . Available from: http://www.tandfonline.com/doi/abs/10.4161/hv.7.12.18111 https://doi.org/10.4161/hv.7.12.18111  PMID: 22108037 
  33. Gouma S, Schurink-Van’t Klooster TM, de Melker HE, Kerkhof J, Smits GP, Hahné SJ, et al. Mumps serum antibody levels before and after an outbreak to assess infection and immunity in vaccinated students. Open Forum Infect Dis. 2014;1(3):ofu101.  https://doi.org/10.1093/ofid/ofu101  PMID: 25734169 
Waning immunity against mumps in vaccinated young adults, France 2013
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Sabine+Vygen&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vygen Sabine</a>, <a href="/search?value1=Aur%C3%A9lie+Fischer&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fischer Aurélie</a>, <a href="/search?value1=Laure+Meurice&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Meurice Laure</a>, <a href="/search?value1=Ibrahim+Mounchetrou+Njoya&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mounchetrou Njoya Ibrahim</a>, <a href="/search?value1=Marina+Gregoris&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gregoris Marina</a>, <a href="/search?value1=Bakhao+Ndiaye&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ndiaye Bakhao</a>, <a href="/search?value1=Adrien+Ghenassia&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ghenassia Adrien</a>, <a href="/search?value1=Isabelle+Poujol&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Poujol Isabelle</a>, <a href="/search?value1=Jean+Paul+Stahl&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Stahl Jean Paul</a>, <a href="/search?value1=Denise+Antona&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Antona Denise</a>, <a href="/search?value1=Yann+Le+Strat&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Le Strat Yann</a>, <a href="/search?value1=Daniel+Levy-Bruhl&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Levy-Bruhl Daniel</a>, <a href="/search?value1=Patrick+Rolland&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rolland Patrick</a></span>. Waning immunity against mumps in vaccinated young adults, France 2013. <a href="/content/ecdc">Euro Surveill.</a> 2016;21(10):pii=30156. <a href="https://doi.org/10.2807/1560-7917.ES.2016.21.10.30156" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2016.21.10.30156</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 21 Apr 2015;&nbsp;&nbsp; <span class="generated">Accepted</span>: 19 Oct 2015 </span> </p>
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