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Abstract

Colistin resistance was detected in 53 of 10,011 (0.5%) by prospective phenotypic testing of consecutive clinical isolates in a single hospital in Barcelona, Spain (2012–15). The gene was retrospectively identified by PCR and sequencing in 15 of 50 available isolates. Each isolate had a unique PFGE pattern except for two. This clonal diversity supports the hypothesis of horizontal dissemination of the gene in the local study population.

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/content/10.2807/1560-7917.ES.2016.21.13.30183
2016-03-31
2024-09-13
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2016.21.13.30183
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Detection of mcr-1 colistin resistance gene in polyclonal Escherichia coli isolates in Barcelona, Spain, 2012 to 2015
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=N%C3%BAria+Prim&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Prim Núria</a>, <a href="/search?value1=Alba+Rivera&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rivera Alba</a>, <a href="/search?value1=Judith+Rodr%C3%ADguez-Navarro&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rodríguez-Navarro Judith</a>, <a href="/search?value1=Montserrat+Espa%C3%B1ol&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Español Montserrat</a>, <a href="/search?value1=Miquel+Turbau&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Turbau Miquel</a>, <a href="/search?value1=Pere+Coll&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Coll Pere</a>, <a href="/search?value1=Beatriz+Mirelis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mirelis Beatriz</a></span>. Detection of mcr-1 colistin resistance gene in polyclonal Escherichia coli isolates in Barcelona, Spain, 2012 to 2015. <a href="/content/ecdc">Euro Surveill.</a> 2016;21(13):pii=30183. <a href="https://doi.org/10.2807/1560-7917.ES.2016.21.13.30183" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2016.21.13.30183</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 15 Mar 2016;&nbsp;&nbsp; <span class="generated">Accepted</span>: 31 Mar 2016 </span> </p>
/content/10.2807/1560-7917.ES.2016.21.13.30183
/content/10.2807/1560-7917.ES.2016.21.13.30183
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