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Abstract

Suboptimal laboratory diagnostics for infection (CDI) impedes its surveillance and control across Europe. We evaluated changes in local laboratory CDI diagnostics and changes in national diagnostic and typing capacity for CDI during the European Infection Surveillance Network (ECDIS-Net) project, through cross-sectional surveys in 33 European countries in 2011 and 2014. In 2011, 126 (61%) of a convenience sample of 206 laboratories in 31 countries completed a survey on local diagnostics. In 2014, 84 (67%) of these 126 laboratories in 26 countries completed a follow-up survey. Among laboratories that participated in both surveys, use of CDI diagnostics deemed ‘optimal’ or ‘acceptable’ increased from 19% to 46% and from 10% to 15%, respectively (p  < 0.001). The survey of national capacity was completed by national coordinators of 31 and 32 countries in 2011 and 2014, respectively. Capacity for any typing method increased from 22/31 countries in 2011 to 26/32 countries in 2014; for PCR ribotyping from 20/31 countries to 23/32 countries, and specifically for capillary PCR ribotyping from 7/31 countries to 16/32 countries. While our study indicates improved diagnostic capability and national capacity for capillary PCR ribotyping across European laboratories between 2011 and 2014, increased use of ‘optimal’ diagnostics should be promoted.

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/content/10.2807/1560-7917.ES.2016.21.29.30292
2016-07-21
2024-04-19
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2016.21.29.30292
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Survey of diagnostic and typing capacity for Clostridium difficile infection in Europe, 2011 and 2014
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Sofie+M+van+Dorp&option1=author&noRedirect=true" class="nonDisambigAuthorLink">van Dorp Sofie M</a>, <a href="/search?value1=Daan+W+Notermans&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Notermans Daan W</a>, <a href="/search?value1=Jeroen+Alblas&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Alblas Jeroen</a>, <a href="/search?value1=Petra+Gastmeier&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gastmeier Petra</a>, <a href="/search?value1=Silja+Mentula&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mentula Silja</a>, <a href="/search?value1=Elisabeth+Nagy&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nagy Elisabeth</a>, <a href="/search?value1=Patrizia+Spigaglia&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Spigaglia Patrizia</a>, <a href="/search?value1=Katiusha+Ivanova&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ivanova Katiusha</a>, <a href="/search?value1=Fidelma+Fitzpatrick&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fitzpatrick Fidelma</a>, <a href="/search?value1=Fr%C3%A9d%C3%A9ric+Barbut&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Barbut Frédéric</a>, <a href="/search?value1=Trefor+Morris&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Morris Trefor</a>, <a href="/search?value1=Mark+H+Wilcox&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wilcox Mark H</a>, <a href="/search?value1=Pete+Kinross&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kinross Pete</a>, <a href="/search?value1=Carl+Suetens&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Suetens Carl</a>, <a href="/search?value1=Ed+J+Kuijper&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Kuijper Ed J</a>, <a href="/search?value1=for+the+European+Clostridium+difficile+Infection+Surveillance+Network+%28ECDIS-Net%29+project+on+behalf+of+all+participants&option1=author&noRedirect=true" class="nonDisambigAuthorLink">for the European Clostridium difficile Infection Surveillance Network (ECDIS-Net) project on behalf of all participants</a></span>. Survey of diagnostic and typing capacity for Clostridium difficile infection in Europe, 2011 and 2014 . <a href="/content/ecdc">Euro Surveill.</a> 2016;21(29):pii=30292. <a href="https://doi.org/10.2807/1560-7917.ES.2016.21.29.30292" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2016.21.29.30292</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 30 Jun 2015;&nbsp;&nbsp; <span class="generated">Accepted</span>: 03 Feb 2016 </span> </p>
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