-
Increase in ECHOvirus 6 infections associated with neurological symptoms in the Netherlands, June to August 2016
- Kimberley SM Benschop1 , Felix Geeraedts2 , Barbara Beuvink3 , Silke A Spit3 , Ewout B Fanoy1,4 , Eric CJ Claas5 , Suzan D Pas6 , Rob Schuurman7 , Jaco J Verweij8 , Sylvia M Bruisten9 , Katja C Wolthers10 , Hubert GM Niesters11 , Marion Koopmans1,6 , Erwin Duizer1 , on behalf of VIRO-TypeNed12
-
View Affiliations Hide AffiliationsAffiliations: 1 Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands 2 Laboratory for Medical Microbiology and Public Health, Hengelo, the Netherlands 3 Public Health Service, Twente, the Netherlands 4 Public Health Service region Utrecht, Zeist, the Netherlands 5 Department of Medical Microbiology, Leiden University Medical Center, Leiden, the Netherlands 6 Department of Viroscience, Erasmus Medical Centre, Rotterdam, the Netherlands 7 Department of Virology, University Medical Center Utrecht, Utrecht, the Netherlands 8 Laboratory of Medical Microbiology and Immunology, St Elisabeth Hospital, Tilburg, the Netherlands 9 Public Health Service, Department of Infectious Diseases, Amsterdam, the Netherlands 10 Department of Medical Microbiology, Academic Medical Center, Amsterdam, the Netherlands 11 Department of Medical Microbiology, Division of Clinical Virology, University Medical Center Groningen, Groningen, the Netherlands 12 http://www.rivm.nl/Onderwerpen/T/Type_Ned/Type_Ned_VirologieKimberley S.M. Benschopk.s.m.benschop gmail.com
-
View Citation Hide Citation
Citation style for this article: Benschop Kimberley SM, Geeraedts Felix, Beuvink Barbara, Spit Silke A, Fanoy Ewout B, Claas Eric CJ, Pas Suzan D, Schuurman Rob, Verweij Jaco J, Bruisten Sylvia M, Wolthers Katja C, Niesters Hubert GM, Koopmans Marion, Duizer Erwin, on behalf of VIRO-TypeNed. Increase in ECHOvirus 6 infections associated with neurological symptoms in the Netherlands, June to August 2016. Euro Surveill. 2016;21(39):pii=30351. https://doi.org/10.2807/1560-7917.ES.2016.21.39.30351 Received: 09 Sept 2016; Accepted: 29 Sept 2016
- Previous Article
- Table of Contents
- Next Article
Abstract
The Dutch virus-typing network VIRO-TypeNed reported an increase in ECHOvirus 6 (E-6) infections with neurological symptoms in the Netherlands between June and August 2016. Of the 31 cases detected from January through August 2016, 15 presented with neurological symptoms. Ten of 15 neurological cases were detected in the same province and the identified viruses were genetically related. This report is to alert medical and public health professionals of the circulation of E-6 associated with neurological symptoms.

Article metrics loading...

-
From This Site
/content/10.2807/1560-7917.ES.2016.21.39.30351dcterms_title,dcterms_subject,pub_keyword-contentType:Journal -contentType:Contributor -contentType:Concept -contentType:Institution105 -
PubMed
-
Google Scholar

Full text loading...
References
-
Niesters HG, Rossen JW, van der Avoort H, Baas D, Benschop K, Claas EC, et al. Laboratory-based surveillance in the molecular era: the TYPENED model, a joint data-sharing platform for clinical and public health laboratories. Euro Surveill. 2013;18(4):20387. PMID: 23369392
-
Nix WA, Oberste MS, Pallansch MA. Sensitive, seminested PCR amplification of VP1 sequences for direct identification of all enterovirus serotypes from original clinical specimens. J Clin Microbiol. 2006;44(8):2698-704. https://doi.org/10.1128/JCM.00542-06 PMID: 16891480
-
Cabrerizo M, Trallero G, Simmonds P. Recombination and evolutionary dynamics of human echovirus 6. J Med Virol. 2014;86(5):857-64. https://doi.org/10.1002/jmv.23741 PMID: 24114692
-
Smura T, Kakkola L, Blomqvist S, Klemola P, Parsons A, Kallio-Kokko H, et al. Molecular evolution and epidemiology of echovirus 6 in Finland. Infect Genet Evol. 2013;16:234-47. https://doi.org/10.1016/j.meegid.2013.02.011 PMID: 23462388
-
Cabrerizo M, Trallero G, Echevarría JE, Moreno-Docón A, Pena MJ, Pérez-Ruiz M, et al. Meningitis, Encephalitis Spanish Study Group. Molecular characterization of enteroviruses associated with neurological infections in Spain, 2008. J Med Virol. 2013;85(11):1975-7. https://doi.org/10.1002/jmv.23693 PMID: 23893817
-
Khetsuriani N, Lamonte A, Oberste MS, Pallansch M. Neonatal enterovirus infections reported to the national enterovirus surveillance system in the United States, 1983-2003. Pediatr Infect Dis J. 2006;25(10):889-93. https://doi.org/10.1097/01.inf.0000237798.07462.32 PMID: 17006282
-
Antona D, Lévêque N, Chomel JJ, Dubrou S, Lévy-Bruhl D, Lina B. Surveillance of enteroviruses in France, 2000-2004. Eur J Clin Microbiol Infect Dis. 2007;26(6):403-12. https://doi.org/10.1007/s10096-007-0306-4 PMID: 17534678
-
Trallero G, Avellon A, Otero A, De Miguel T, Pérez C, Rabella N, et al. Enteroviruses in Spain over the decade 1998-2007: virological and epidemiological studies. J Clin Virol. 2010;47(2):170-6. https://doi.org/10.1016/j.jcv.2009.11.013 PMID: 20007023
-
Kim HJ, Kang B, Hwang S, Hong J, Kim K, Cheon DS. Epidemics of viral meningitis caused by echovirus 6 and 30 in Korea in 2008. Virol J. 2012;9(1):38. https://doi.org/10.1186/1743-422X-9-38 PMID: 22336050
-
Janes VA, Minnaar R, Koen G, van Eijk H, Dijkman-de Haan K, Pajkrt D, et al. Presence of human non-polio enterovirus and parechovirus genotypes in an Amsterdam hospital in 2007 to 2011 compared to national and international published surveillance data: a comprehensive review. Euro Surveill. 2014;19(46):20964. https://doi.org/10.2807/1560-7917.ES2014.19.46.20964 PMID: 25425513
-
van der Sanden SM, Koopmans MP, van der Avoort HG. Detection of human enteroviruses and parechoviruses as part of the national enterovirus surveillance in the Netherlands, 1996-2011. Eur J Clin Microbiol Infect Dis. 2013;32(12):1525-31. https://doi.org/10.1007/s10096-013-1906-9 PMID: 23780695
-
Benschop KS, Rahamat-Langendoen JC, van de Avoort HG, Claas ECJ, Pas SD, Schuurman R, et al. VIRO-TypeNed, systematic molecular surveillance of enteroviruses in the Netherlands between 2010 and 2014. Euro Surveill. 2016;21(39):30352.
-
European Centre for Disease Prevention and Control (ECDC). Enterovirus detections associated with severe neurological symptoms in children and adults in European countries. Stockholm: ECDC; 8 August 2016. Available from: http://ecdc.europa.eu/en/publications/Publications/01-08-2016-RRA-Enterovirus%2071-Spain,%20France,%20Netherlands.pdf
-
Wildenbeest JG, van den Broek PJ, Benschop KS, Koen G, Wierenga PC, Vossen AC, et al. Pleconaril revisited: clinical course of chronic enteroviral meningoencephalitis after treatment correlates with in vitro susceptibility. Antivir Ther. 2012;17(3):459-66. https://doi.org/10.3851/IMP1936 PMID: 22293148
-
Benschop KS, van der Avoort HG, Duizer E, Koopmans MP. Antivirals against enteroviruses: a critical review from a public-health perspective. Antivir Ther. 2015;20(2):121-30. https://doi.org/10.3851/IMP2939 PMID: 25643052
-
Thibaut HJ, De Palma AM, Neyts J. Combating enterovirus replication: state-of-the-art on antiviral research. Biochem Pharmacol. 2012;83(2):185-92. https://doi.org/10.1016/j.bcp.2011.08.016 PMID: 21889497

Data & Media loading...
