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  1. Sax H, Bloemberg G, Hasse B, Sommerstein R, Kohler P, Achermann Y, et al. Prolonged Outbreak of Mycobacterium chimaera Infection After Open-Chest Heart Surgery. Clin Infect Dis. 2015;61(1):67-75.  https://doi.org/10.1093/cid/civ198  PMID: 25761866 
  2. European Centre for Disease Prevention and Control (ECDC). Invasive cardiovascular infection by Mycobacterium chimaera potentially associated with heater-cooler units used during cardiac surgery. 2015. Stockholm: ECDC. 30 Apr 2015. Available from: http://ecdc.europa.eu/en/publications/Publications/mycobacterium-chimaera-infection-associated-with-heater-cooler-units-rapid-risk-assessment-30-April-2015.pdf
  3. Centers for Disease Control and Prevention (CDC). Non-tuberculous Mycobacterium (NTM) Infections and Heater-Cooler Devices Interim Practical Guidance: Updated October 27, 2015. Atlanta: CDC. 27 Oct 2015. Available from: http://www.cdc.gov/hai/pdfs/outbreaks/cdc-notice-heater-cooler-units-final-clean.pdf
  4. Haller S, Höller C, Jacobshagen A, Hamouda O, Abu Sin M, Monnet DL, et al. Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: results of an outbreak investigation in Germany, April 2015 to February 2016. Euro Surveill. 2016;21(17):30215.  https://doi.org/10.2807/1560-7917.ES.2016.21.17.30215  PMID: 27168588 
  5. Götting T, Klassen S, Jonas D, Benk Ch, Serr A, Wagner D, et al. Heater-cooler units: contamination of crucial devices in cardiothoracic surgery. J Hosp Infect. 2016;93(3):223-8.  https://doi.org/10.1016/j.jhin.2016.02.006  PMID: 27101883 
  6. Sommerstein R, Rüegg C, Kohler P, Bloemberg G, Kuster SP, Sax H. Transmission of Mycobacterium chimaera from Heater-Cooler Units during Cardiac Surgery despite an Ultraclean Air Ventilation System. Emerg Infect Dis. 2016;22(6):1008-13.  https://doi.org/10.3201/eid2206.160045  PMID: 27070958 
  7. Perkins KM, Lawsin A, Hasan NA, Strong M, Halpin AL, Rodger RR, et al. Notes from the Field: Mycobacterium chimaera Contamination of Heater-Cooler Devices Used in Cardiac Surgery - United States. MMWR Morb Mortal Wkly Rep. 2016;65(40):1117-8.  https://doi.org/10.15585/mmwr.mm6540a6  PMID: 27740609 
  8. Robinson JO, Coombs GW, Speers DJ, Keehner T, Keil AD, D’Abrera V, et al. Mycobacterium chimaera colonisation of heater–cooler units in Western Australia, 2015: investigation of possible iatrogenic infection using whole genome sequencing. Euro Surveill. 2016;21(46):22640.
  9. Delaunay S, Kahn P, Tatay M, Liu J. Knowledge sharing during public health emergencies: from global call to effective implementation. Bull World Health Organ. 2016;94(4):236-236A.  https://doi.org/10.2471/BLT.16.172650  PMID: 27034513 
  10. World Health Organization (WHO). Developing global norms for sharing data and results during public health emergencies. Statement arising from a WHO Consultation held on 1-2 September 2015. [Internet]. WHO: Geneva. Sep 2015. Available from: http://www.who.int/medicines/ebola-treatment/blueprint_phe_data-share-results/en/
  11. Trudzinski FC, Schlotthauer U, Kamp A, Hennemann K, Muellenbach RM, Reischl U, et al. Clinical implications of Mycobacterium chimaera detection in thermoregulatory devices used for extracorporeal membrane oxygenation (ECMO), Germany, 2015 to 2016. Euro Surveill. 2016;21(46):22641.
  12. U. S. Food and Drug Administration. UPDATE: Mycobacterium chimaera Infections Associated with LivaNova PLC (formerly Sorin Group Deutschland GmbH) Stӧckert 3T Heater-Cooler System: FDA Safety Communication [Internet]. 2016 [updated 14 Oct 2016; cited 2016 24 Oct 2016]. Available from: http://www.fda.gov/MedicalDevices/Safety/AlertsandNotices/ucm520191.htm.
  13. Group S. 3T Field Safety Notice Update - October 13, 2016. [Accessed 24 Oct 2016]. Available from: http://www.livanova.sorin.com/products/cardiac-surgery/perfusion/hlm/3t
  14. European Centre for Disease Prevention and Control (ECDC). EU protocol for case detection, laboratory diagnosis and environmental testing of Mycobacterium chimaera infections potentially associated with heater-cooler units: case definition and environmental testing methodology. Stockholm: ECDC. Aug 2015. Available from: http://ecdc.europa.eu/en/publications/Publications/EU-protocol-for-M-chimaera.pdf
  15. Centers for Disease Control and Prevention (CDC). Contaminated Devices Putting Open-Heart Surgery Patients at Risk. Atlanta: CDC. 13 Oct 2016. Available from: http://www.cdc.gov/media/releases/2016/p1013-contaminated-devices-.html
  16. U. S. Food and Drug Administration (FDA). FDA's Ongoing Investigation of Nontuberculous Mycobacteria Infections Associated with Heater-Cooler Devices. Silver Spring: FDA. 13 Oct 2016. Available from: http://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/CardiovascularDevices/Heater-CoolerDevices/ucm492590.htm
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