- Manmohan Parida1, Paban Kumar Dash1, Jyoti S Kumar1, Gaurav Joshi1, Kundan Tandel1, Shashi Sharma1, Ambuj Srivastava1, Ankita Agarwal1, Amrita Saha1, Shweta Saraswat1, Divyanshi Karothia1, Vatsala Malviya1
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View Affiliations Hide AffiliationsAffiliations: 1 Division of Virology, Defence Research & Development Establishment (DRDE), Gwalior, IndiaManmohan Paridaparidamm rediffmail.com
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Citation style for this article: Parida Manmohan, Dash Paban Kumar, Kumar Jyoti S, Joshi Gaurav, Tandel Kundan, Sharma Shashi, Srivastava Ambuj , Agarwal Ankita, Saha Amrita, Saraswat Shweta, Karothia Divyanshi, Malviya Vatsala. Emergence of influenza A(H1N1)pdm09 genogroup 6B and drug resistant virus, India, January to May 2015. Euro Surveill. 2016;21(5):pii=30124. https://doi.org/10.2807/1560-7917.ES.2016.21.5.30124 Received: 11 Dec 2015; Accepted: 04 Feb 2016
Emergence of influenza A(H1N1)pdm09 genogroup 6B and drug resistant virus, India, January to May 2015
Abstract
To investigate the aetiology of the 2015 A(H1N1)pdm09 influenza outbreak in India, 1,083 nasopharyngeal swabs from suspect patients were screened for influenza A(H1N1)pdm09 in the state of Madhya Pradesh. Of 412 positive specimens, six were further characterised by phylogenetic analysis of haemagglutinin (HA) sequences revealing that they belonged to genogroup 6B. A new mutation (E164G) was observed in HA2 of two sequences. Neuraminidase genes in two of 12 isolates from fatal cases on prior oseltamivir treatment harboured the H275Y mutation.

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