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Abstract

Implementation of pneumococcal conjugate vaccines in the Netherlands (PCV7 in 2006 and PCV10 in 2011) for infants caused a shift in serotypes in invasive pneumococcal disease (IPD). We explored sex differences in serotype-specific IPD incidence before and after vaccine introduction. Incidences in the pre-PCV7 (June 2004–May 2006), post-PCV7 (June 2008–May 2011) and post-PCV10 period (June 2013–May 2015), stratified by age, were compared. Incidence was higher in men for all age groups (overall in men: 16.7, 15.5 and 14.4/100,000 and women: 15.4, 13.6 and 13.9/100,000 pre-PCV7, post-PCV7 and post-PCV10, respectively), except for 20–39 year-olds after PCV7 and 40–64 year-olds after PCV10 introduction. After PCV7 and PCV10 introduction, the overall IPD incidence decreased in men aged 20–39 years (from 5.3 pre-PCV7 to 4.7 and 2.6/100,000 post-PCV7 and post-PCV10, respectively), whereas it showed a temporary increase in women (from 3.9/100,000 pre-PCV7 to 5.0/100,000 post-PCV7 and back to 4.0/100,000 post-PCV10) due to replacement disease. PCV10 herd effects were observed throughout, but in women older than 40 years, a significant increase in non-PCV10 serotype offset a decrease in overall IPD incidence. Ongoing surveillance of IPD incidence by sex is important to evaluate the long-term effects of PCV implementation.

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/content/10.2807/1560-7917.ES.2017.22.10.30481
2017-03-09
2024-09-16
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2017.22.10.30481
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References

  1. Fish EN. The X-files in immunity: sex-based differences predispose immune responses. Nat Rev Immunol. 2008;8(9):737-44.  https://doi.org/10.1038/nri2394  PMID: 18728636 
  2. Roberts CW, Walker W, Alexander J. Sex-associated hormones and immunity to protozoan parasites. Clin Microbiol Rev. 2001;14(3):476-88.  https://doi.org/10.1128/CMR.14.3.476-488.2001  PMID: 11432809 
  3. Kadioglu A, Cuppone AM, Trappetti C, List T, Spreafico A, Pozzi G, et al. Sex-based differences in susceptibility to respiratory and systemic pneumococcal disease in mice. J Infect Dis. 2011;204(12):1971-9.  https://doi.org/10.1093/infdis/jir657  PMID: 22021621 
  4. van Lunzen J, Altfeld M. Sex differences in infectious diseases-common but neglected. J Infect Dis. 2014;209(Suppl 3):S79-80.  https://doi.org/10.1093/infdis/jiu159  PMID: 24966193 
  5. Falagas ME, Mourtzoukou EG, Vardakas KZ. Sex differences in the incidence and severity of respiratory tract infections. Respir Med. 2007;101(9):1845-63.  https://doi.org/10.1016/j.rmed.2007.04.011  PMID: 17544265 
  6. Gutiérrez F, Masiá M, Mirete C, Soldán B, Rodríguez JC, Padilla S, et al. The influence of age and gender on the population-based incidence of community-acquired pneumonia caused by different microbial pathogens. J Infect. 2006;53(3):166-74.  https://doi.org/10.1016/j.jinf.2005.11.006  PMID: 16375972 
  7. Jensen-Fangel S, Mohey R, Johnsen SP, Andersen PL, Sørensen HT, Ostergaard L. Gender differences in hospitalization rates for respiratory tract infections in Danish youth. Scand J Infect Dis. 2004;36(1):31-6.  https://doi.org/10.1080/00365540310017618  PMID: 15000556 
  8. Millett ER, Quint JK, Smeeth L, Daniel RM, Thomas SL. Incidence of community-acquired lower respiratory tract infections and pneumonia among older adults in the United Kingdom: a population-based study. PLoS One. 2013;8(9):e75131.  https://doi.org/10.1371/journal.pone.0075131  PMID: 24040394 
  9. Usuf E, Bottomley C, Adegbola RA, Hall A. Pneumococcal carriage in sub-Saharan Africa--a systematic review. PLoS One. 2014;9(1):e85001.  https://doi.org/10.1371/journal.pone.0085001  PMID: 24465464 
  10. Watson K, Carville K, Bowman J, Jacoby P, Riley TV, Leach AJ, et al. Upper respiratory tract bacterial carriage in Aboriginal and non-Aboriginal children in a semi-arid area of Western Australia. Pediatr Infect Dis J. 2006;25(9):782-90.  https://doi.org/10.1097/01.inf.0000232705.49634.68  PMID: 16940834 
  11. Syrjänen RK, Kilpi TM, Kaijalainen TH, Herva EE, Takala AK. Nasopharyngeal carriage of Streptococcus pneumoniae in Finnish children younger than 2 years old. J Infect Dis. 2001;184(4):451-9.  https://doi.org/10.1086/322048  PMID: 11471103 
  12. van Gils EJ, Veenhoven RH, Hak E, Rodenburg GD, Bogaert D, Ijzerman EP, et al. Effect of reduced-dose schedules with 7-valent pneumococcal conjugate vaccine on nasopharyngeal pneumococcal carriage in children: a randomized controlled trial. JAMA. 2009;302(2):159-67.  https://doi.org/10.1001/jama.2009.975  PMID: 19584345 
  13. Spijkerman J, van Gils EJ, Veenhoven RH, Hak E, Yzerman EP, van der Ende A, et al. Carriage of Streptococcus pneumoniae 3 years after start of vaccination program, the Netherlands. Emerg Infect Dis. 2011;17(4):584-91.  https://doi.org/10.3201/eid1704.101115  PMID: 21470445 
  14. Jansen AG, Rodenburg GD, van der Ende A, van Alphen L, Veenhoven RH, Spanjaard L, et al. Invasive pneumococcal disease among adults: associations among serotypes, disease characteristics, and outcome. Clin Infect Dis. 2009;49(2):e23-9.  https://doi.org/10.1086/600045  PMID: 19522653 
  15. Rodenburg GD, de Greeff SC, Jansen AG, de Melker HE, Schouls LM, Hak E, et al. Effects of pneumococcal conjugate vaccine 2 years after its introduction, the Netherlands. Emerg Infect Dis. 2010;16(5):816-23.  https://doi.org/10.3201/eid1605.091223  PMID: 20409372 
  16. van Deursen AM, van Mens SP, Sanders EA, Vlaminckx BJ, de Melker HE, Schouls LM, et al. Invasive pneumococcal disease and 7-valent pneumococcal conjugate vaccine, the Netherlands. Emerg Infect Dis. 2012;18(11):1729-37.  https://doi.org/10.3201/eid1811.120329  PMID: 23092683 
  17. Myint TT, Madhava H, Balmer P, Christopoulou D, Attal S, Menegas D, et al. The impact of 7-valent pneumococcal conjugate vaccine on invasive pneumococcal disease: a literature review. Adv Ther. 2013;30(2):127-51.  https://doi.org/10.1007/s12325-013-0007-6  PMID: 23397399 
  18. Ladhani SN, Slack MP, Andrews NJ, Waight PA, Borrow R, Miller E. Invasive pneumococcal disease after routine pneumococcal conjugate vaccination in children, England and Wales. Emerg Infect Dis. 2013;19(1):61-8.  https://doi.org/10.3201/eid1901.120741  PMID: 23259937 
  19. Griffin MR, Zhu Y, Moore MR, Whitney CG, Grijalva CGUS. U.S. hospitalizations for pneumonia after a decade of pneumococcal vaccination. N Engl J Med. 2013;369(2):155-63.  https://doi.org/10.1056/NEJMoa1209165  PMID: 23841730 
  20. de St Maurice A, Schaffner W, Griffin MR, Halasa N, Grijalva CG. Persistent Sex Disparities in Invasive Pneumococcal Diseases in the Conjugate Vaccine Era. J Infect Dis. 2016;214(5):792-7.  https://doi.org/10.1093/infdis/jiw222  PMID: 27247342 
  21. van Lier EA, Oomen PJ, Mulder M, Conyn-van Spaendonck MAE, Drijfhout IH, de Hoogh PAAM, de Melker HE. Vaccinatiegraad Rijksvaccinatieprogramma Nederland Verslagjaar 2013. [Immunisation coverage national immunisation programme in the Netherlands: year of report 2013]. Bilthoven: Rijksinstituut voor Volksgezondheid en Milieu. 2013. RIVM Rapport 150202001. Dutch. Available from: http://www.rivm.nl/en/Documents_and_publications/Scientific/Reports/2013/juni/Immunisation_coverage_National_Immunisation_Programme_in_the_Netherlands_Year_of_report_2013
  22. Hak E, Shea KM, Jick SS. Association of infant pneumococcal vaccination with pneumococcal pneumonia among mothers: a nested case-control study using the GPRD. Vaccine. 2013;31(12):1590-6.  https://doi.org/10.1016/j.vaccine.2013.01.018  PMID: 23357195 
  23. Van Mens SP, Van Deursen AM, Meijvis SC, Vlaminckx BJ, Sanders EA, De Melker HE, et al. Increased incidence of serotype-1 invasive pneumococcal disease in young female adults in The Netherlands. Epidemiol Infect. 2014;142(9):1996-9.  https://doi.org/10.1017/S0950268813002860  PMID: 24229845 
  24. Harboe ZB, Benfield TL, Valentiner-Branth P, Hjuler T, Lambertsen L, Kaltoft M, et al. Temporal trends in invasive pneumococcal disease and pneumococcal serotypes over 7 decades. Clin Infect Dis. 2010;50(3):329-37.  https://doi.org/10.1086/649872  PMID: 20047478 
  25. Wagenvoort GH, Sanders EA, Vlaminckx BJ, Elberse KE, de Melker HE, van der Ende A, et al. Invasive pneumococcal disease: Clinical outcomes and patient characteristics 2-6 years after introduction of 7-valent pneumococcal conjugate vaccine compared to the pre-vaccine period, the Netherlands. Vaccine. 2016;34(8):1077-85.  https://doi.org/10.1016/j.vaccine.2015.12.066  PMID: 26778420 
  26. Rothman K, Greenland S. Chapter 15: Introduction to stratified analysis. In: Rothman K, Greenland S, editors. Modern epidemiology. 3rd ed. Philadelphia: Wolters Kluwer; 2008. p. 258-282.
  27. Muenchhoff M, Goulder PJ. Sex differences in pediatric infectious diseases. J Infect Dis. 2014;209(Suppl 3):S120-6.  https://doi.org/10.1093/infdis/jiu232  PMID: 24966192 
  28. Liptzin DR, Landau LI, Taussig LM. Sex and the lung: Observations, hypotheses, and future directions. Pediatr Pulmonol. 2015;50(12):1159-69.  https://doi.org/10.1002/ppul.23178  PMID: 25906765 
  29. Voysey M, Barker CI, Snape MD, Kelly DF, Trück J, Pollard AJ. Sex-dependent immune responses to infant vaccination: an individual participant data meta-analysis of antibody and memory B cells. Vaccine. 2016;34(14):1657-64.  https://doi.org/10.1016/j.vaccine.2016.02.036  PMID: 26920472 
  30. Jungers P, Chauveau P, Descamps-Latscha B, Labrunie M, Giraud E, Man NK, et al. Age and gender-related incidence of chronic renal failure in a French urban area: a prospective epidemiologic study. Nephrol Dial Transplant. 1996;11(8):1542-6.  https://doi.org/10.1093/oxfordjournals.ndt.a027610  PMID: 8856208 
  31. Nuorti JP, Butler JC, Farley MM, Harrison LH, McGeer A, Kolczak MS, et al. Cigarette smoking and invasive pneumococcal disease. N Engl J Med. 2000;342(10):681-9.  https://doi.org/10.1056/NEJM200003093421002  PMID: 10706897 
  32. Inverarity D, Lamb K, Diggle M, Robertson C, Greenhalgh D, Mitchell TJ, et al. Death or survival from invasive pneumococcal disease in Scotland: associations with serogroups and multilocus sequence types. J Med Microbiol. 2011;60(Pt 6):793-802.  https://doi.org/10.1099/jmm.0.028803-0  PMID: 21393453 
  33. Flasche S, Van Hoek AJ, Sheasby E, Waight P, Andrews N, Sheppard C, et al. Effect of pneumococcal conjugate vaccination on serotype-specific carriage and invasive disease in England: a cross-sectional study. PLoS Med. 2011;8(4):e1001017.  https://doi.org/10.1371/journal.pmed.1001017  PMID: 21483718 
  34. de Greeff SC, de Melker HE, Westerhof A, Schellekens JF, Mooi FR, van Boven M. Estimation of household transmission rates of pertussis and the effect of cocooning vaccination strategies on infant pertussis. Epidemiology. 2012;23(6):852-60.  https://doi.org/10.1097/EDE.0b013e31826c2b9e  PMID: 23018969 
Sex differences in invasive pneumococcal disease and the impact of pneumococcal conjugate vaccination in the Netherlands, 2004 to 2015
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Gertjan+H+J+Wagenvoort&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wagenvoort Gertjan H J</a>, <a href="/search?value1=Elisabeth+A+M+Sanders&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sanders Elisabeth A M</a>, <a href="/search?value1=Bart+J+Vlaminckx&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vlaminckx Bart J</a>, <a href="/search?value1=Hester+E+de+Melker&option1=author&noRedirect=true" class="nonDisambigAuthorLink">de Melker Hester E</a>, <a href="/search?value1=Arie+van+der+Ende&option1=author&noRedirect=true" class="nonDisambigAuthorLink">van der Ende Arie</a>, <a href="/search?value1=Mirjam+J+Knol&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Knol Mirjam J</a></span>. Sex differences in invasive pneumococcal disease and the impact of pneumococcal conjugate vaccination in the Netherlands, 2004 to 2015. <a href="/content/ecdc">Euro Surveill.</a> 2017;22(10):pii=30481. <a href="https://doi.org/10.2807/1560-7917.ES.2017.22.10.30481" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2017.22.10.30481</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 08 Jun 2016;&nbsp;&nbsp; <span class="generated">Accepted</span>: 06 Sept 2016 </span> </p>
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