1887
  1. Home
  2. Eurosurveillance
  3. Volume 22, Issue 5, 02/Feb/2017
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

Since 14 November 2016, 38 cases of hepatitis A have been notified in Berlin; of these, 37 were male and 30 reported to have sex with men (MSM). Median age of MSM cases is 31 years (range: 24–52 years). Phylogenetic analysis revealed three distinct sequences, linking cases in Berlin to those in other German cities and to clusters recognised in other European countries in 2016.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2017.22.5.30457
2017-02-02
2024-09-16
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2017.22.5.30457
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/22/5/eurosurv-22-5-1.html?itemId=/content/10.2807/1560-7917.ES.2017.22.5.30457&mimeType=html&fmt=ahah

References

  1. Robert Koch Institut (RKI). Falldefinitionen des Robert Koch-Instituts zur Übermittlung von Erkrankungs- oder Todesfällen und Nachweisen von Krankheitserregern, Ausgabe 2015. [Case definitions of the Robert Koch Institute for the surveillance of notifiable infectious diseases in Germany, Edition 2015]. German. Available from: http://www.rki.de/DE/Content/Infekt/IfSG/Falldefinition/Downloads/Falldefinitionen_des_RKI.pdf?__blob=publicationFile
  2. Harries M, Monazahian M, Wenzel J, Jilg W, Weber M, Ehlers J, et al. Foodborne hepatitis A outbreak associated with bakery products in northern Germany, 2012. Euro Surveill. 2014;19(50):20992.  https://doi.org/10.2807/1560-7917.ES2014.19.50.20992  PMID: 25597541 
  3. National Institute for Public Health and the Environment (RIVM). Ministry of Health, Welfare and Sport. Protocol. Molecular detection and typing of VP1-2A region of Hepatitis A Virus (HAV). Bilthoven: RIVM. [Accessed 19 Jan 2017]. Available from: http://www.rivm.nl/dsresource?objectid=87925ed7-72d0-4d4f-8b53-fa309fe45b87&type=org&disposition=inline
  4. European Centre for Disease Prevention and Control (ECDC). Hepatitis A outbreaks in the EU/EEA mostly affecting men who have sex with men. Stockholm: ECDC. 19 Dec 2016. Available from: http://ecdc.europa.eu/en/publications/Publications/13-12-2016-RRA-Hepatitis%20A-United%20Kingdom.pdf
  5. Bruni R, Taffon S, Equestre M, Chionne P, Madonna E, Rizzo C, et al. Italian National Task Force on Hepatitis A. Key Role of Sequencing to Trace Hepatitis A Viruses Circulating in Italy During a Large Multi-Country European Foodborne Outbreak in 2013. PLoS One. 2016;11(2):e0149642.  https://doi.org/10.1371/journal.pone.0149642  PMID: 26901877 
  6. Mao JS, Yu PH, Ding ZS, Chen NL, Huang BZ, Xie RY, et al. Patterns of shedding of hepatitis A virus antigen in feces and of antibody responses in patients with naturally acquired type A hepatitis. J Infect Dis. 1980;142(5):654-9.  https://doi.org/10.1093/infdis/142.5.654  PMID: 6257794 
  7. Cotter SM, Sansom S, Long T, Koch E, Kellerman S, Smith F, et al. Outbreak of hepatitis A among men who have sex with men: implications for hepatitis A vaccination strategies. J Infect Dis. 2003;187(8):1235-40.  https://doi.org/10.1086/374057  PMID: 12696002 
  8. Spada E, Genovese D, Tosti ME, Mariano A, Cuccuini M, Proietti L, et al. An outbreak of hepatitis A virus infection with a high case-fatality rate among injecting drug users. J Hepatol. 2005;43(6):958-64.  https://doi.org/10.1016/j.jhep.2005.06.012  PMID: 16143420 
  9. Robert Koch Institut (RKI). Statement of the German Standing Committee on Vaccination at the RKI. Recommendations of the Standing Committee on Vaccination. (STIKO) at the Robert Koch Institute/Effective: August 2015. Epidemiol Bull. 2015;332(34). Available from: http://www.rki.de/EN/Content/infections/Vaccination/recommandations/34_2015_engl.pdf?__blob=publicationFile
  10. Faber MS, Stark K, Behnke SC, Schreier E, Frank C. Epidemiology of hepatitis A virus infections, Germany, 2007-2008. Emerg Infect Dis. 2009;15(11):1760-8.  https://doi.org/10.3201/eid1511.090214  PMID: 19891863 
  11. Victor JC, Monto AS, Surdina TY, Suleimenova SZ, Vaughan G, Nainan OV, et al. Hepatitis A vaccine versus immune globulin for postexposure prophylaxis. N Engl J Med. 2007;357(17):1685-94.  https://doi.org/10.1056/NEJMoa070546  PMID: 17947390 
  12. Robert Koch Institut (RKI). Gehäuftes Auftreten von Hepatitis-A-Erkrankungen bei Männern, die Sex mit Männern haben [Increased incidence of hepatitis A among men who have sex with men]. Epidemiol Bull. 2017;2:28. German. Available from: http://www.rki.de/DE/Content/Infekt/EpidBull/Archiv/2017/Ausgaben/02_17.pdf?__blob=publicationFile
  13. Sfetcu O, Irvine N, Ngui SL, Emerson C, McCaughey C, Donaghy P. Hepatitis A outbreak predominantly affecting men who have sex with men in Northern Ireland, October 2008 to July 2009. Euro Surveill. 2011;16(9):19808. PMID: 21392487 
Ongoing outbreaks of hepatitis A among men who have sex with men (MSM), Berlin, November 2016 to January 2017 – linked to other German cities and European countries
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Dirk+Werber&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Werber Dirk</a>, <a href="/search?value1=Kai+Michaelis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Michaelis Kai</a>, <a href="/search?value1=Marius+Hausner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Hausner Marius</a>, <a href="/search?value1=Dagmar+Sissolak&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sissolak Dagmar</a>, <a href="/search?value1=J%C3%BCrgen+Wenzel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Wenzel Jürgen</a>, <a href="/search?value1=Julia+Bitzegeio&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bitzegeio Julia</a>, <a href="/search?value1=Anne+Belting&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Belting Anne</a>, <a href="/search?value1=Daniel+Sagebiel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sagebiel Daniel</a>, <a href="/search?value1=Mirko+Faber&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Faber Mirko</a></span>. Ongoing outbreaks of hepatitis A among men who have sex with men (MSM), Berlin, November 2016 to January 2017 – linked to other German cities and European countries. <a href="/content/ecdc">Euro Surveill.</a> 2017;22(5):pii=30457. <a href="https://doi.org/10.2807/1560-7917.ES.2017.22.5.30457" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2017.22.5.30457</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 20 Jan 2017;&nbsp;&nbsp; <span class="generated">Accepted</span>: 02 Feb 2017 </span> </p>
/content/10.2807/1560-7917.ES.2017.22.5.30457
/content/10.2807/1560-7917.ES.2017.22.5.30457
Loading

Data & Media loading...

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error