- Sandra Dudareva-Vizule1,2, Karin Haar1, Andrea Sailer1, Klaus Jansen1, Osamah Hamouda1, Hilmar Wisplinghoff3,4,5, Carsten Tiemann6, Eberhard Pape1, Viviane Bremer1, Chlamydia trachomatis laboratory sentinel team7
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View Affiliations Hide AffiliationsAffiliations: 1 Department for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany 2 Charité University Medicine, Berlin, Germany 3 Wisplinghoff Laboratories, Cologne, Germany 4 Institute for Medical Microbiology, University of Cologne, Cologne, Germany 5 Institute for Microbiology, University Witten/Herdecke, Witten, Germany 6 Labor Krone, Bad Salzuflen, Germany 7 The Chlamydia trachomatis laboratory sentinel team is listed at the end of the articleSandra Dudareva-VizuleDudareva-VizuleS rki.de
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Citation style for this article: Dudareva-Vizule Sandra, Haar Karin, Sailer Andrea, Jansen Klaus, Hamouda Osamah, Wisplinghoff Hilmar, Tiemann Carsten, Pape Eberhard, Bremer Viviane, Chlamydia trachomatis laboratory sentinel team. Establishment of a voluntary electronic Chlamydia trachomatis laboratory surveillance system in Germany, 2008 to 2014. Euro Surveill. 2017;22(6):pii=30459. https://doi.org/10.2807/1560-7917.ES.2017.22.6.30459 Received: 26 Feb 2016; Accepted: 08 Sep 2016
Establishment of a voluntary electronic Chlamydia trachomatis laboratory surveillance system in Germany, 2008 to 2014
Abstract
Chlamydia trachomatis (CT) infections are not reportable in Germany and limited data on prevalence are available. CT screening has been offered free of charge to pregnant women since 1995 and to all women under 25 years since 2008. For symptomatic women and men, diagnostic testing is covered by statutory health insurance. We describe the establishment of a nationwide, laboratory-based, voluntary sentinel that electronically collects information on all performed CT tests with test results, test reason and patient information. The sentinel represents one third of all performed CT tests in Germany. In the period from 2008 to 2014, 3,877,588 CT tests were reported, 93% in women. Women aged 20–24 years and men aged 25–29 years were the most frequently tested age groups. The overall proportion of positive tests (PPT) among women was 3.9% and among men 11.0%. The highest PPT among women was in the age groups 15–19 (6.8%) and 20–24 years (5.9%), and among men in the age groups 20–24 (19.2%), 15–19 (15.4%) and 25–29 years (14.8%). The PPT for CT was high among women and men younger than 25 years. Prevention is urgently needed. Monitoring of CT infection in Germany should be continued.

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References
-
World Health Organisation (WHO). Global incidence and prevalence of selected curable sexually transmitted infections. Geneva: WHO; 2012. Available from: http://www.who.int/reproductivehealth/publications/rtis/stisestimates/en/
-
European Centre for Disease Prevention and Control (ECDC). Sexually transmitted infections in Europe - 2011. Stockholm: ECDC; 2013. Available from: http://ecdc.europa.eu/en/publications/Publications/sexually-transmitted-infections-Europe-2011.pdf
-
European Centre for Disease Prevention and Control (ECDC). Chlamydia control in Europe: literature review. Stockholm: ECDC; 2014. Available from: http://ecdc.europa.eu/en/publications/Publications/chlamydia-control-europe.pdf
-
Marrazzo JM, Celum CL, Hillis SD, Fine D, DeLisle S, Handsfield HH. Performance and cost-effectiveness of selective screening criteria for Chlamydia trachomatis infection in women. Implications for a national Chlamydia control strategy. Sex Transm Dis. 1997;24(3):131-41. https://doi.org/10.1097/00007435-199703000-00003 PMID: 9132979
-
Paavonen J, Puolakkainen M, Paukku M, Sintonen H. Cost-benefit analysis of first-void urine Chlamydia trachomatis screening program. Obstet Gynecol. 1998;92(2):292-8. PMID: 9699769
-
Howell MR, Gaydos JC, McKee KT Jr, Quinn TC, Gaydos CA. Control of Chlamydia trachomatis infections in female army recruits: cost-effective screening and treatment in training cohorts to prevent pelvic inflammatory disease. Sex Transm Dis. 1999;26(9):519-26. https://doi.org/10.1097/00007435-199910000-00007 PMID: 10534206
-
Scholes D, Stergachis A, Heidrich FE, Andrilla H, Holmes KK, Stamm WE. Prevention of pelvic inflammatory disease by screening for cervical chlamydial infection. N Engl J Med. 1996;334(21):1362-6. https://doi.org/10.1056/NEJM199605233342103 PMID: 8614421
-
Kamwendo F, Forslin L, Bodin L, Danielsson D. Decreasing incidences of gonorrhea- and chlamydia-associated acute pelvic inflammatory disease. A 25-year study from an urban area of central Sweden. Sex Transm Dis. 1996;23(5):384-91. https://doi.org/10.1097/00007435-199609000-00007 PMID: 8885069
-
Liu B, Roberts CL, Clarke M, Jorm L, Hunt J, Ward J. Chlamydia and gonorrhoea infections and the risk of adverse obstetric outcomes: a retrospective cohort study. Sex Transm Infect. 2013;89(8):672-8. https://doi.org/10.1136/sextrans-2013-051118 PMID: 24005255
-
Baud D, Goy G, Jaton K, Osterheld MC, Blumer S, Borel N, et al. Role of Chlamydia trachomatis in miscarriage. Emerg Infect Dis. 2011;17(9):1630-5. https://doi.org/10.3201/eid1709.100865 PMID: 21888787
-
Ehrhard I. Epidemiologische Aspekte bei Neisseria gonorrhoeae- und Chlamydia trachomatis-Infektionen, unter besonderer Berücksichtigung der Meldedaten in Sachsen. Der Mikrobiologe.2012;22(4):111-9.
-
Haar K, Bremer V, Houareau C, Meyer T, Desai S, Thamm M, et al. Risk factors for Chlamydia trachomatis infection in adolescents: results from a representative population-based survey in Germany, 2003-2006. Euro Surveill. 2013;18(34):20562. https://doi.org/10.2807/1560-7917.ES2013.18.34.20562 PMID: 23987832
-
Hamouda O, Bremer V, Marcus U, Bartmeyer B. [Epidemiological developments of selected sexually transmitted infections in Germany]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013;56(12):1600-8. German. https://doi.org/10.1007/s00103-013-1866-3 PMID: 24337121
-
Desai S, Meyer T, Thamm M, Hamouda O, Bremer V. Prevalence of Chlamydia trachomatis among young German adolescents, 2005-06. Sex Health. 2011;8(1):120-2. https://doi.org/10.1071/SH10036 PMID: 21371394
-
Bremer V, Hofmann A, Hamouda O. Epidemiologie der Chlamydia-trachomatis-Infektionen. [Epidemiology of chlamydial infections]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. 2007;58(1):18-23. German Available from: https://www.springermedizin.de/epidemiologie-der-chlamydia-trachomatis-infektionen/8024840
-
Bremer V, Marcus U, Hofmann A, Hamouda O. Building a sentinel surveillance system for sexually transmitted infections in Germany, 2003. Sex Transm Infect. 2005;81(2):173-9. https://doi.org/10.1136/sti.2004.009878 PMID: 15800099
-
Robert Koch-Institut. Sechs Jahre STD-Sentinel-Surveillance in Deutschland – Zahlen und Fakten. [Six years of STI sentinel surveillance in Germany – numbers and facts]. Epidemiologisches Bulletin.2010;3:20-7. German. Available from: http://edoc.rki.de/documents/rki_fv/re9N7X7TjXxE/PDF/2730NT0nnm1tEA.pdf
-
Zahlenbericht der privaten Krankenversicherung. [Indices report of the private health Insurance 2011/2012]. Berlin, Köln: Verband der deutschen Krankenversicherung e.V. [Association of the German Health Insurance]. [Accessed: 15 Sep 2015]. German. Available from:
-
Mund M, Sander G, Potthoff P, Schicht H, Matthias K. Introduction of Chlamydia trachomatis screening for young women in Germany. JDDG - Journal of the German Society of Dermatology. 2008;6(12):1032-7. http://dx.doi.org/10.1111/j.1610-0387.2008.06743.x
-
Balabanova Y, Gilsdorf A, Buda S, Burger R, Eckmanns T, Gärtner B, et al. Communicable diseases prioritized for surveillance and epidemiological research: results of a standardized prioritization procedure in Germany, 2011. PLoS One. 2011;6(10):e25691. https://doi.org/10.1371/journal.pone.0025691 PMID: 21991334
-
Schmidt D, Päschke H, Bremer V, Hamouda O, Reischl U, Sailer A, et al. An assessment of the current Chlamydia trachomatis laboratory practices in Germany. Gesundheitswesen. 2014;76(10):e44-50. PMID: 24203685
-
Fenton KA, Lowndes CM. Recent trends in the epidemiology of sexually transmitted infections in the European Union. Sex Transm Infect. 2004;80(4):255-63. https://doi.org/10.1136/sti.2004.009415 PMID: 15295121
-
Fenton KA, Korovessis C, Johnson AM, McCadden A, McManus S, Wellings K, et al. Sexual behaviour in Britain: reported sexually transmitted infections and prevalent genital Chlamydia trachomatis infection. Lancet. 2001;358(9296):1851-4. https://doi.org/10.1016/S0140-6736(01)06886-6 PMID: 11741624
-
van den Broek IVF, van Bergen JEAM, Brouwers EEHG, Fennema JSA, Götz HM, Hoebe CJPA, et al. Effectiveness of yearly, register based screening for chlamydia in the Netherlands: controlled trial with randomised stepped wedge implementation. BMJ. 2012;345:e4316. https://doi.org/10.1136/bmj.e4316
-
Goulet V, de Barbeyrac B, Raherison S, Prudhomme M, Semaille C, Warszawski J, et al. . Prevalence of Chlamydia trachomatis: results from the first national population-based survey in France. Sex Transm Infect. 2010;86(4):263-70. https://doi.org/10.1136/sti.2009.038752 PMID: 20660590
-
Klavs I, Rodrigues LC, Wellings K, Kese D, Hayes R. Prevalence of genital Chlamydia trachomatis infection in the general population of Slovenia: serious gaps in control. Sex Transm Infect. 2004;80(2):121-3. https://doi.org/10.1136/sti.2003.005900 PMID: 15054174
-
Public Health England. Sexually transmitted infections and chlamydia screening in England, 2015. Health Protection Report. 2016;10(22). Available from: https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/559993/hpr2216_stis_CRRCTD4.pdf
-
Kløvstad H, Aavitsland P. Denominators count: supplementing surveillance data for genital Chlamydia trachomatis infection with testing data, Norway, 2007 to 2013. Euro Surveill. 2015;20(36):30012. https://doi.org/10.2807/1560-7917.ES.2015.20.36.30012 PMID: 26535784
-
Heywood W, Patrick K, Smith AM, Pitts MK. Associations between early first sexual intercourse and later sexual and reproductive outcomes: a systematic review of population-based data. Arch Sex Behav. 2015;44(3):531-69. https://doi.org/10.1007/s10508-014-0374-3 PMID: 25425161
-
Dudareva-Vizule S, Haar K, Sailer A, Wisplinghoff H, Wisplinghoff F, Marcus U, et al. . Prevalence of pharyngeal and rectal Chlamydia trachomatis and Neisseria gonorrhoeae infections among men who have sex with men in Germany. Sex Transm Infect. 2014;90(1):46-51. https://doi.org/10.1136/sextrans-2012-050929 PMID: 23920398
-
European Centre for Disease Prevention and Control (ECDC). Chlamydia control in Europe - a survey of Member States. Stockholm: ECDC; 2014. Available from: http://ecdc.europa.eu/en/publications/Publications/0906_GUI_Chlamydia_Control_in_Europe.pdf
-
Bundszentrale fuer gesundheitliche Aufklaerung (BZgA). AIDS im öffentlichen Bewusstsein der Bundesrepublik Deutschland 2012. [AIDS in public perception in Germany 2012]. Cologne: BZgA; 2013. German. Available from: http://www.bzga.de/forschung/studien-untersuchungen/studien/aidspraevention/?sub=76

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