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Abstract

From January to June 2018, two ongoing hepatitis A outbreaks affected travellers returning from Morocco and cases in Europe without travel history, resulting in 163 patients in eight European countries. Most interviewed travel-related cases were unaware of the hepatitis A risk in Morocco. Molecular analysis revealed two distinct hepatitis A virus (HAV) strains (subgenotype IA DK2018_231; subgenotype IB V18–16428). Vaccination recommendations should be emphasised to increase awareness among non-immune travellers to Morocco and HAV-endemic countries.

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/content/10.2807/1560-7917.ES.2018.23.27.1800329
2018-07-05
2024-03-19
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2018.23.27.1800329
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References

  1. Frank C, Walter J, Muehlen M, Jansen A, van Treeck U, Hauri AM, et al. Major outbreak of hepatitis A associated with orange juice among tourists, Egypt, 2004. Emerg Infect Dis. 2007;13(1):156-8.  https://doi.org/10.3201/eid1301.060487  PMID: 17370535 
  2. Amon JJ, Devasia R, Xia G, Nainan OV, Hall S, Lawson B, et al. Molecular epidemiology of foodborne hepatitis a outbreaks in the United States, 2003. J Infect Dis. 2005;192(8):1323-30.  https://doi.org/10.1086/462425  PMID: 16170748 
  3. Wheeler C, Vogt TM, Armstrong GL, Vaughan G, Weltman A, Nainan OV, et al. An outbreak of hepatitis A associated with green onions. N Engl J Med. 2005;353(9):890-7.  https://doi.org/10.1056/NEJMoa050855  PMID: 16135833 
  4. Koroglu M, Jacobsen KH, Demiray T, Ozbek A, Erkorkmaz U, Altindis M. Socioeconomic indicators are strong predictors of hepatitis A seroprevalence rates in the Middle East and North Africa. J Infect Public Health. 2017;10(5):513-7.  https://doi.org/10.1016/j.jiph.2016.09.020  PMID: 28162965 
  5. Jacobsen KH, Wiersma ST. Hepatitis A virus seroprevalence by age and world region, 1990 and 2005. Vaccine. 2010;28(41):6653-7.  https://doi.org/10.1016/j.vaccine.2010.08.037  PMID: 20723630 
  6. D’Andrea L, Pérez-Rodríguez FJ, de Castellarnau M, Manzanares S, Lite J, Guix S, et al. Hepatitis A virus genotype distribution during a decade of universal vaccination of preadolescents. Int J Mol Sci. 2015;16(4):6842-54.  https://doi.org/10.3390/ijms16046842  PMID: 25815599 
  7. Faber MS, Stark K, Behnke SC, Schreier E, Frank C. Epidemiology of hepatitis A virus infections, Germany, 2007-2008. Emerg Infect Dis. 2009;15(11):1760-8.  https://doi.org/10.3201/eid1511.090214  PMID: 19891863 
  8. European Centre for Disease Prevention and Control (ECDC). Multi-country outbreak of hepatitis A virus genotype IA infections affecting EU countries in 2018 – 21 May 2018 Stockholm: ECDC; 2018. Available from: https://ecdc.europa.eu/sites/portal/files/documents/21-05-2018-RRA-Hepatitis-A-multicountry-outbreak-EU.pdf.
  9. Beauté J, Westrell T, Schmid D, Müller L, Epstein J, Kontio M, et al. Travel-associated hepatitis A in Europe, 2009 to 2015. Euro Surveill. 2018;23(22):1700583.  https://doi.org/10.2807/1560-7917.ES.2018.23.22.1700583  PMID: 29871720 
  10. Severi E, Verhoef L, Thornton L, Guzman-Herrador BR, Faber M, Sundqvist L, et al. Large and prolonged food-borne multistate hepatitis A outbreak in Europe associated with consumption of frozen berries, 2013 to 2014. Euro Surveill. 2015;20(29):21192.  https://doi.org/10.2807/1560-7917.ES2015.20.29.21192  PMID: 26227370 
  11. Gillesberg Lassen S, Soborg B, Midgley SE, Steens A, Vold L, Stene-Johansen K, et al. Ongoing multi-strain food-borne hepatitis A outbreak with frozen berries as suspected vehicle: four Nordic countries affected, October 2012 to April 2013. Euro Surveill. 2013;18(17):20467.  https://doi.org/https://10.2807/ese.18.17.20467  PMID: 23647625 
  12. Fournet N, Baas D, van Pelt W, Swaan C, Ober H, Isken L, et al. Another possible food-borne outbreak of hepatitis A in the Netherlands indicated by two closely related molecular sequences, July to October 2011. Euro Surveill. 2012;17(6):20079.  https://doi.org/https://10.2807/ese.17.06.20079  PMID: 22340976 
  13. Carvalho C, Thomas H, Balogun K, Tedder R, Pebody R, Ramsay M, et al. A possible outbreak of hepatitis A associated with semi-dried tomatoes, England, July-November 2011. Euro Surveill. 2012;17(6):20083.  https://doi.org/https://10.2807/ese.17.06.20083  PMID: 22340975 
  14. European Centre for Disease Prevention and Control (ECDC). Hepatitis A virus in the EU/EEA, 1975-2014. Stockholm: ECDC; 2016. Available from: https://ecdc.europa.eu/sites/portal/files/media/en/publications/Publications/hepatitis-a-virus-EU-EEA-1975-2014.pdf
  15. World Health Organization (WHO). WHO position paper on hepatitis A vaccines – June 2012. Wkly Epidemiol Rec. 2012;87(28/29):261-76. PMID: 22905367 
  16. MacDonald E, Steens A, Stene-Johansen K, Gillesberg Lassen S, Midgley S, Lawrence J, et al. Increase in hepatitis A in tourists from Denmark, England, Germany, the Netherlands, Norway and Sweden returning from Egypt, November 2012 to March 2013. Euro Surveill. 2013;18(17):20468.  https://doi.org/https://10.2807/ese.18.17.20468  PMID: 23647624 
  17. Sane J, MacDonald E, Vold L, Gossner C, Severi E, on behalf of the International OutbOutbreak Investigation Team. Multistate foodborne hepatitis A outbreak among European tourists returning from Egypt--need for reinforced vaccination recommendations, November 2012 to April 2013. Euro Surveill. 2015;20(4):21018.  https://doi.org/10.2807/1560-7917.ES2015.20.4.21018  PMID: 25655054 
  18. Ward M, Borgen K, Mazick A, Muehlen M. Hepatitis A vaccination policy for travellers to Egypt in eight European countries, 2004. Euro Surveill. 2006;11(1):592.  https://doi.org/10.2807/esm.11.01.00592-en 
  19. Whelan J, Sonder G, van den Hoek A. Declining incidence of hepatitis A in Amsterdam (The Netherlands), 1996-2011: second generation migrants still an important risk group for virus importation. Vaccine. 2013;31(14):1806-11.  https://doi.org/10.1016/j.vaccine.2013.01.053  PMID: 23395735 
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