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Abstract

We conducted a hospital-based test-negative study in Hong Kong to estimate influenza vaccine effectiveness (VE) for the winter of 2017/18. The interim analysis included data on 1,078 children admitted between 4 December 2017 and 31 January 2018 with febrile acute respiratory illness and tested for influenza. We estimated influenza VE at 66% (95% confidence interval (CI): 43–79) overall, and 65% (95% CI: 40–80) against influenza B, the dominant virus type (predominantly B/Yamagata).

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/content/10.2807/1560-7917.ES.2018.23.8.18-00062
2018-02-22
2024-03-19
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2018.23.8.18-00062
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References

  1. Jackson ML, Chung JR, Jackson LA, Phillips CH, Benoit J, Monto AS, et al. Influenza Vaccine Effectiveness in the United States during the 2015-2016 Season. N Engl J Med. 2017;377(6):534-43.  https://doi.org/10.1056/NEJMoa1700153  PMID: 28792867 
  2. Leung VK, Cowling BJ, Feng S, Sullivan SG. Concordance of interim and final estimates of influenza vaccine effectiveness: a systematic review. Euro Surveill. 2016;21(16):30202.  https://doi.org/10.2807/1560-7917.ES.2016.21.16.30202  PMID: 27124573 
  3. Jackson ML, Nelson JC. The test-negative design for estimating influenza vaccine effectiveness. Vaccine. 2013;31(17):2165-8.  https://doi.org/10.1016/j.vaccine.2013.02.053  PMID: 23499601 
  4. Sullivan SG, Feng S, Cowling BJ. Potential of the test-negative design for measuring influenza vaccine effectiveness: a systematic review. Expert Rev Vaccines. 2014;13(12):1571-91.  https://doi.org/10.1586/14760584.2014.966695  PMID: 25348015 
  5. Cowling BJ, Chan KH, Feng S, Chan EL, Lo JY, Peiris JS, et al. The effectiveness of influenza vaccination in preventing hospitalizations in children in Hong Kong, 2009-2013. Vaccine. 2014;32(41):5278-84.  https://doi.org/10.1016/j.vaccine.2014.07.084  PMID: 25092636 
  6. Chiu SS, Feng S, Chan KH, Lo JY, Chan EL, So LY, et al. Hospital-based vaccine effectiveness against influenza B lineages, Hong Kong, 2009-14. Vaccine. 2016;34(19):2164-9.  https://doi.org/10.1016/j.vaccine.2016.03.032  PMID: 27013437 
  7. Cowling BJ, Kwan MY, Wong JS, Feng S, Leung CW, Chan EL, et al. Interim estimates of the effectiveness of influenza vaccination against influenza-associated hospitalization in children in Hong Kong, 2015-16. Influenza Other Respi Viruses. 2017;11(1):61-5.  https://doi.org/10.1111/irv.12399  PMID: 27313064 
  8. Center for Health Protection Hong Kong. Local Situation of Influenza Activity (as of Aug 30, 2017). 2018;14(34). Hong Kong: Center for Health Protection; 31 Aug 2017. Available from: https://www.chp.gov.hk/files/pdf/fluexpress_web_week34_31_8_2017_eng.pdf
  9. Centre for Health Protection Hong Kong. Influenza virus subtyping. Hong Kong: Center for Health Protection. [Accessed: 8 Feb 2018]. Available from: https://www.chp.gov.hk/en/statistics/data/10/641/643/2275.html
  10. Belongia EA, Simpson MD, King JP, Sundaram ME, Kelley NS, Osterholm MT, et al. Variable influenza vaccine effectiveness by subtype: a systematic review and meta-analysis of test-negative design studies. Lancet Infect Dis. 2016;16(8):942-51.  https://doi.org/10.1016/S1473-3099(16)00129-8  PMID: 27061888 
  11. Skowronski DM, Chambers C, De Serres G, Dickinson JA, Winter AL, Hickman R, et al. Early season co-circulation of influenza A(H3N2) and B(Yamagata): interim estimates of 2017/18 vaccine effectiveness, Canada, January 2018. Euro Surveill. 2018;23(5).  https://doi.org/10.2807/1560-7917.ES.2018.23.5.18-00035  PMID: 29409570 
  12. Castilla J, Navascués A, Casado I, Pérez-García A, Aguinaga A, Ezpeleta G, et al. Network for Influenza Surveillance in Hospitals of Navarre. Interim effectiveness of trivalent influenza vaccine in a season dominated by lineage mismatched influenza B, northern Spain, 2017/18. Euro Surveill. 2018;23(7):18-00057.
  13. Flannery B, Chung JR, Belongia EA, McLean HQ, Gaglani M, Murthy K, et al. Interim estimates of 2017-18 seasonal influenza vaccine effectiveness - United States, February 2018. MMWR Morb Mortal Wkly Rep. 2018;67(6):180-5.  https://doi.org/10.15585/mmwr.mm6706a2  PMID: 29447141 
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