Rapid communication Open Access
Like 1


We report an ongoing measles outbreak in Manaus, Amazonas state, Brazil. As at 3 November 2018, 1,631 cases were confirmed corresponding to an incidence of 75.3 per 100,000 inhabitants; all five sanitary districts presented confirmed cases. Reintroduction of measles virus in Manaus is likely related to the current outbreak in Venezuela and due to recent decline in measles vaccine coverage. Given the current scenario, prevention and control measures should target individuals aged 15–29 years.


Article metrics loading...

Loading full text...

Full text loading...



  1. Ministry of Health (MoH). Brazil. Informe nº 26/2018 - Situação do Sarampo no Brasil – 2018. [Epidemiological Update Measles in Brazil, 2018]. Brasília: MoH; 2018. Portuguese. Available from: http://portalarquivos2.saude.gov.br/images/pdf/2018/outubro/10/informe-sarampo-26-9out18.pdf
  2. Ministry of health (MoH). Brazil. Situação do Sarampo no Brasil – 2018 [Status of Measles in Brazil - 2018]. Brasília: MoH; 2018. Portuguese. Available from: http://portalarquivos2.saude.gov.br/images/pdf/2018/dezembro/14/Informe-Sarampo-n34-12dez18.pdf
  3. Ministry of Health (MoH). Brazil. Confirmed cases of measles. Brazil, major regions and federal units, 1990 to 2018. Brasília: MoH; 2018. Available from: http://portalarquivos2.saude.gov.br/images/pdf/2018/abril/25/Casos-confirmados-sarampo.pdf
  4. Ministry of Health (MoH). Brazil. National Immunization Program (NIP): 40 years. Brasília: MoH; 2013. Available from: http://bvsms.saude.gov.br/bvs/publicacoes/programa_nacional_imunizacoes_pni40.pdf
  5. World Health Organization (WHO). Response to measles outbreaks in measles mortality reduction setting. WHO/IB/09/03. P5. Geneva: WHO; 2009. Available from: http://apps.who.int/iris/bitstream/handle/10665/70047/WHO_IVB_09.03_eng.pdf?sequence=1
  6. Ministry of Health (MoH). Brazil. Guia de Vigilância em Saúde. [Guide to Health Surveillance]. Brasília: MoH; 2017. Available at: http://portalarquivos.saude.gov.br/images/pdf/2017/outubro/06/Volume-Unico-2017.pdf
  7. Centers for Disease Control and Prevention (CDC). Manual for the surveillance of Vaccine-Preventable Diseases. Chapter 7: Measles. Atlanta: CDC; 2018. Available from: https://www.cdc.gov/vaccines/pubs/surv-manual/chpt07-measles.html
  8. Ministry of Health (MoH). Brazil. Nota informativa n° 384, de 2016. Sobre mudanças no calendário nacional de vacinação para o ano de 2017. [Informative note n ° 384, of 2016. About changes in the national vaccination calendar for the year 2017]. Brasília: MoH; 2017. Portuguese. Available from: http://portalarquivos.saude.gov.br/images/pdf/2016/dezembro/28/Nota-Informativa-384-Calendario-Nacional-de-Vacinacao-2017.pdf
  9. Ministry of Health (MoH). Brazil. National Immunization Program Information System (SIPNI) Brasília: MoH; 2018. Available from: http://sipni.datasus.gov.br/si-pni-web/faces/relatorio/consolidado/dosesAplicadasMensal.jsf.
  10. Domingues CMAS. Teixeira AMdS. Vaccination coverage and impact on vaccine-preventable diseases in Brazil between 1982 and 2012: National Immunization Program progress and challenges. Epidemiol Serv Saúde.2013;22(1):9-27.  https://doi.org/10.5123/S1679-49742013000100002 
  11. Ministry of Health (MoH). Brazil. Situação do Sarampo no Brasil – 2018 [Status of Measles in Brazil - 2018]. Brasília: MoH; 2018. Portuguese. Available from: http://portalarquivos2.saude.gov.br/images/pdf/2018/outubro/03/informe-sarampo-25-3out18.pdf
  12. Ministry of Health (MoH). Brazil. Secretaria de Vigilância em Saúde. Sarampo: Situação Epidemiológica [Ministry of Health Surveillance. Measles: Epidemiological Situation]. Brasília: MoH; 2018. Available from: http://portalms.saude.gov.br/saude-de-a-z/sarampo-situacao-epidemiologica
  13. Pan American Health Organization/World Health Organization (PAHO/WHO). Measles elimination: field guide. Washington, D.C.: PAHO; 2005. Available from: http://www1.paho.org/hq/dmdocuments/2010/FieldGuide_Measles_2ndEd_e.pdf
  14. World Health Organization (WHO). Measles – Brazil: Disease outbreak news 2018. Geneva: WHO; 2018. Available from: https://www.who.int/csr/don/11-june-2018-measles-brazil/en/.
  15. Pan American Health Organization / World Health Organization (PAHO/WHO). PAHO urges rapid increase in vaccination coverage to stop spread of measles in the Americas 2018. Washington D.C: PAHO; 2018. Available from: https://www.paho.org/hq/index.php?option=com_content&view=article&id=14582:paho-urges-rapid-increase-in-vaccination-coverage-to-stop-spread-of-measles-in-the-americas&Itemid=1926&lang=en

Data & Media loading...

Comment has been disabled for this content
Submit comment
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error