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Abstract

Data on features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents are scarce. We report preliminary results of an Italian multicentre study comprising 168 laboratory-confirmed paediatric cases (median: 2.3 years, range: 1 day–17.7 years, 55.9% males), of which 67.9% were hospitalised and 19.6% had comorbidities. Fever was the most common symptom, gastrointestinal manifestations were frequent; two children required intensive care, five had seizures, 49 received experimental treatments and all recovered.

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/content/10.2807/1560-7917.ES.2020.25.18.2000600
2020-05-07
2024-03-29
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2020.25.18.2000600
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References

  1. Bialek S, Gierke R, Hughes M, McNamara LA, Pilishvili T, Skoff T, CDC COVID-19 Response Team. Coronavirus disease 2019 in children - United States, February 12-April 2, 2020. MMWR Morb Mortal Wkly Rep. 2020;69(14):422-6.  https://doi.org/10.15585/mmwr.mm6914e4  PMID: 32271728 
  2. Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 Infection in Children. N Engl J Med. 2020;382(17):1663-5.  https://doi.org/10.1056/NEJMc2005073  PMID: 32187458 
  3. European Centre for Disease Prevention and Control (ECDC). Rapid risk assessment. Coronavirus disease 2019 (COVID-19) in the EU/EEA and the UK – eighth update. Stockholm: ECDC; 2020. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/covid-19-rapid-risk-assessment-coronavirus-disease-2019-eighth-update-8-april-2020.pdf
  4. Epicentro, Istituto Superiore di Sanità (ISS). Epidemia COVID-19. Aggiornamento nazionale 9 aprile 2020 – ore 16:00. [COVID-19 epidemic. 9 April 2020 national update – 4 pm]. Rome: ISS; 10 April 2020. Italian. Available from: https://www.epicentro.iss.it/coronavirus/bollettino/Bollettino-sorveglianza-integrata-COVID-19_9-aprile-2020.pdf
  5. Onder G, Rezza G, Brusaferro S. Case-fatality rate and characteristics of patients dying in relation to COVID-19 in Italy. JAMA. 2020.  https://doi.org/10.1001/jama.2020.4683  PMID: 32203977 
  6. Lee PI, Hu YL, Chen PY, Huang YC, Hsueh PR. Are children less susceptible to COVID-19? J Microbiol Immunol Infect. 2020. PMID: 32147409 
  7. Italian Ministry of Health. Rapporto annuale sull’attività di ricovero ospedaliero (DATI SDO 2018). [Annual report on hospitalization activity. Hospital discharge records data 2018]. Rome: Italian Ministry of Health; 2020. Italian. Available from: http://www.salute.gov.it/portale/documentazione/p6_2_2_1.jsp?lingua=italiano&id=2898
  8. Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020; e20200702.  https://doi.org/10.1542/peds.2020-0702  PMID: 32179660 
  9. Qiu H, Wu J, Hong L, Luo Y, Song Q, Chen D. Clinical and epidemiological features of 36 children with coronavirus disease 2019 (COVID-19) in Zhejiang, China: an observational cohort study. Lancet Infect Dis. 2020.  https://doi.org/10.1016/S1473-3099(20)30198-5  PMID: 32220650 
  10. She J, Liu L, Liu W. COVID-19 epidemic: Disease characteristics in children. J Med Virol. 2020.  https://doi.org/10.1002/jmv.25807  PMID: 32232980 
  11. Ludvigsson JF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 2020.  https://doi.org/10.1111/apa.15270  PMID: 32202343 
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