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The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 is of clinical relevance and should be monitored closely.


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