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Abstract

We assess the feasibility of reaching the herd immunity threshold against SARS-CoV-2 through vaccination, considering vaccine effectiveness (VE), transmissibility of the virus and the level of pre-existing immunity in populations, as well as their age structure. If highly transmissible variants of concern become dominant in areas with low levels of naturally-acquired immunity and/or in populations with large proportions of < 15 year-olds, control of infection without non-pharmaceutical interventions may only be possible with a VE ≥ 80%, and coverage extended to children.

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/content/10.2807/1560-7917.ES.2021.26.20.2100428
2021-05-20
2021-09-18
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.20.2100428
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