1887
Rapid communication Open Access
Like 0

Abstract

Prioritisation of elderly people in COVID-19 vaccination campaigns aimed at reducing severe outcomes in this group. Using EU/EEA surveillance and vaccination uptake, we estimated the risk ratio of case, hospitalisation and death notifications in people 80 years and older compared with 25–59-year-olds. Highest impact was observed for full vaccination uptake 80% or higher with reductions in notification rates of cases up to 65% (IRR: 0.35; 95% CI: 0.13–0.99), hospitalisations up to 78% (IRR: 0.22; 95% CI: 0.13–0.37) and deaths up to 84% (IRR: 0.16; 95% CI: 0.13–0.20).

Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2021.26.48.2101030
2021-12-02
2022-01-20
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.48.2101030
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/26/48/eurosurv-26-48-1.html?itemId=/content/10.2807/1560-7917.ES.2021.26.48.2101030&mimeType=html&fmt=ahah

References

  1. European Centre for Disease Prevention and Control (ECDC). Overview of the implementation of COVID-19 vaccination strategies and vaccine deployment plans in the EU/EEA – 1 February 2021. Stockholm: ECDC; 2021. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/Overview-of-COVID-19-vaccination-strategies-deployment-plans-in-the-EU-EEA.pdf
  2. European Centre for Disease Prevention Control (ECDC). Overview of the implementation of COVID-19 vaccination strategies and vaccine deployment plans in the EU/EEA: 6 May 2021. Stockholm: ECDC; 2021. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/covid-19-overview-vaccination-strategies-deployment-plans-6-may-2021.pdf
  3. Spiteri G, Fielding J, Diercke M, Campese C, Enouf V, Gaymard A, et al. First cases of coronavirus disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020. Euro Surveill. 2020;25(9):2000178.  https://doi.org/10.2807/1560-7917.ES.2020.25.9.2000178  PMID: 32156327 
  4. European Centre for Disease Prevention and Control (ECDC). Case definition for coronavirus disease 2019 (COVID-19), as of 3 December 2020. Stockholm: ECDC; 2020. Available from: https://www.ecdc.europa.eu/en/covid-19/surveillance/case-definition
  5. European Centre for Disease Prevention and Control (ECDC). COVID-19 situation update for the EU/EEA, as of 29 November 2021. Stockholm: ECDC; 2021. Available from: https://www.ecdc.europa.eu/en/cases-2019-ncov-eueea
  6. European Centre for Disease Prevention and Control (ECDC). COVID-19 Vaccine Tracker. Stockholm: ECDC. [Accessed: 31 Oct 2021]. Available from: https://vaccinetracker.ecdc.europa.eu/public/extensions/COVID-19/vaccine-tracker.html#uptake-tab
  7. European Centre for Disease Prevention Control (ECDC). COVID-19 Surveillance report Week 43, 2021. Stockholm: ECDC. 4 Nov 2021. Available from: https://covid19-surveillance-report.ecdc.europa.eu/
  8. Harder T, Külper-Schiek W, Reda S, Treskova-Schwarzbach M, Koch J, Vygen-Bonnet S, et al. Effectiveness of COVID-19 vaccines against SARS-CoV-2 infection with the Delta (B.1.617.2) variant: second interim results of a living systematic review and meta-analysis, 1 January to 25 August 2021. Euro Surveill. 2021;26(41):2100920.  https://doi.org/10.2807/1560-7917.ES.2021.26.41.2100920  PMID: 34651577 
  9. Harder T, Koch J, Vygen-Bonnet S, Külper-Schiek W, Pilic A, Reda S, et al. Efficacy and effectiveness of COVID-19 vaccines against SARS-CoV-2 infection: interim results of a living systematic review, 1 January to 14 May 2021. Euro Surveill. 2021;26(28):2100563.  https://doi.org/10.2807/1560-7917.ES.2021.26.28.2100563  PMID: 34269175 
  10. European Centre for Disease Prevention and Control (ECDC). Objectives of vaccination strategies against COVID19. Stockholm: ECDC; 23 Apr 2021. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/Objectives-of-vaccination-strategies-against-COVID-19.pdf
  11. European Centre for Disease Prevention and Control (ECDC). Interim public health considerations for the provision of additional COVID-19 vaccine doses. Stockholm: ECDC; 1 Sep 2021. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/Interim-public-health-considerations-for-the-provision-of-additional-COVID-19-vaccine-doses.pdf
  12. European Centre for Disease Prevention and Control (ECDC). Overview of the implementation of COVID-19 vaccination strategies and vaccine deployment plans in the EU/EEA – 29 March 2021. Stockholm: ECDC; 29 Mar 2021. Available from: https://www.ecdc.europa.eu/sites/default/files/documents/Overview-implementation-COVID-19-vaccination-strategies-vaccine-deployment-plans.pdf
  13. Remschmidt C, Wichmann O, Harder T. Frequency and impact of confounding by indication and healthy vaccinee bias in observational studies assessing influenza vaccine effectiveness: a systematic review. BMC Infect Dis. 2015;15(1):429.  https://doi.org/10.1186/s12879-015-1154-y  PMID: 26474974 
  14. Levine-Tiefenbrun M, Yelin I, Alapi H, Katz R, Herzel E, Kuint J, et al. Viral loads of Delta-variant SARS-CoV2 breakthrough infections following vaccination and booster with the BNT162b2 vaccine. medRxiv. 2021.08.29.21262798v1.  https://doi.org/10.1101/2021.08.29.21262798 
  15. Goldberg Y, Mandel M, Bar-On YM, Bodenheimer O, Freedman L, Haas EJ, et al. Waning immunity of the BNT162b2 vaccine: A nationwide study from Israel. medRxiv. 2021.08.24.21262423v1.  https://doi.org/10.1101/2021.08.24.21262423 
/content/10.2807/1560-7917.ES.2021.26.48.2101030
Loading

Data & Media loading...

Supplementary data

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error