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Abstract

We report the performance of a variety of commercially available SARS-CoV-2 PCR kits, used in several different sites across Ireland to determine if C values across platforms are comparable. We also investigate whether a C value, a surrogate for calculated viral loads in the absence of viral culture of > 34 can be used to exclude SARS-CoV-2 infection and its complications. We found a variation in Cvalues from different assays for the same calculated viral load; this should be taken into consideration for result interpretation.

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/content/10.2807/1560-7917.ES.2021.26.6.2002079
2021-02-11
2024-04-26
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2021.26.6.2002079
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Comparison and correlation of commercial SARS-CoV-2 real-time-PCR assays, Ireland, June 2020
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Anne+Carroll&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Carroll Anne</a>, <a href="/search?value1=Eleanor+McNamara&option1=author&noRedirect=true" class="nonDisambigAuthorLink">McNamara Eleanor</a></span>. Comparison and correlation of commercial SARS-CoV-2 real-time-PCR assays, Ireland, June 2020. <a href="/content/ecdc">Euro Surveill.</a> 2021;26(6):pii=2002079. <a href="https://doi.org/10.2807/1560-7917.ES.2021.26.6.2002079" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2021.26.6.2002079</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 11 Dec 2020;&nbsp;&nbsp; <span class="generated">Accepted</span>: 11 Feb 2021 </span> </p>
/content/10.2807/1560-7917.ES.2021.26.6.2002079
/content/10.2807/1560-7917.ES.2021.26.6.2002079
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