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Abstract

We explored the risk factors associated with SARS-CoV-2 reinfections in Italy between August 2021 and March 2022. Regardless of the prevalent virus variant, being unvaccinated was the most relevant risk factor for reinfection. The risk of reinfection increased almost 18-fold following emergence of the Omicron variant compared with Delta. A severe first SARS-CoV-2 infection and age over 60 years were significant risk factors for severe reinfection.

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/content/10.2807/1560-7917.ES.2022.27.20.2200372
2022-05-19
2025-07-19
/content/10.2807/1560-7917.ES.2022.27.20.2200372
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Risk and protective factors for SARS-CoV-2 reinfections, surveillance data, Italy, August 2021 to March 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Chiara+Sacco&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sacco Chiara</a>, <a href="/search?value1=Daniele+Petrone&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Petrone Daniele</a>, <a href="/search?value1=Martina+Del+Manso&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Del Manso Martina</a>, <a href="/search?value1=Alberto+Mateo-Urdiales&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mateo-Urdiales Alberto</a>, <a href="/search?value1=Massimo+Fabiani&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Fabiani Massimo</a>, <a href="/search?value1=Marco+Bressi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bressi Marco</a>, <a href="/search?value1=Antonino+Bella&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bella Antonino</a>, <a href="/search?value1=Patrizio+Pezzotti&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pezzotti Patrizio</a>, <a href="/search?value1=Maria+Cristina+Rota&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rota Maria Cristina</a>, <a href="/search?value1=Flavia+Riccardo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Riccardo Flavia</a>, <a href="/search?value1=on+behalf+of+the+Italian+Integrated+Surveillance+of+COVID-19+study+group&option1=author&noRedirect=true" class="nonDisambigAuthorLink">on behalf of the Italian Integrated Surveillance of COVID-19 study group</a></span>. Risk and protective factors for SARS-CoV-2 reinfections, surveillance data, Italy, August 2021 to March 2022. <a href="/content/ecdc">Euro Surveill.</a> 2022;27(20):pii=2200372. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.20.2200372" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.20.2200372</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 02 May 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 19 May 2022 </span> </p>
/content/10.2807/1560-7917.ES.2022.27.20.2200372
/content/10.2807/1560-7917.ES.2022.27.20.2200372
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