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Between 7 and 25 May, 86 monkeypox cases were confirmed in the United Kingdom (UK). Only one case is known to have travelled to a monkeypox virus (MPXV) endemic country. Seventy-nine cases with information were male and 66 reported being gay, bisexual, or other men who have sex with men. This is the first reported sustained MPXV transmission in the UK, with human-to-human transmission through close contacts, including in sexual networks. Improving case ascertainment and onward-transmission preventive measures are ongoing.


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  1. World Health Organization (WHO). Monkeypox. Geneva: WHO; 19 May 2022. Available from: https://www.who.int/news-room/fact-sheets/detail/monkeypox
  2. Vaughan A, Aarons E, Astbury J, Balasegaram S, Beadsworth M, Beck CR, et al. Two cases of monkeypox imported to the United Kingdom, September 2018. Euro Surveill. 2018;23(38):1800509.  https://doi.org/10.2807/1560-7917.ES.2018.23.38.1800509  PMID: 30255836 
  3. Vaughan A, Aarons E, Astbury J, Brooks T, Chand M, Flegg P, et al. Human-to-Human Transmission of Monkeypox Virus, United Kingdom, October 2018. Emerg Infect Dis. 2020;26(4):782-5.  https://doi.org/10.3201/eid2604.191164  PMID: 32023204 
  4. UK Health Security Agency (UKHSA). Guidance: Monkeypox: Background information. London: UKHSA; Published: 8 Sep 2018; Updated: 24 May 2022. [Accessed 26 May 2022]. Available from: https://www.gov.uk/guidance/monkeypox
  5. Hobson G, Adamson J, Adler H, Firth R, Gould S, Houlihan C, et al. Family cluster of three cases of monkeypox imported from Nigeria to the United Kingdom, May 2021. Euro Surveill. 2021;26(32):2100745.  https://doi.org/10.2807/1560-7917.ES.2021.26.32.2100745  PMID: 34387184 
  6. European Centre for Disease Prevention and Control (ECDC). Epidemiological update: Monkeypox multi-country outbreak. Stockholm: ECDC; 25 May 2022. Available from: https://www.ecdc.europa.eu/en/news-events/epidemiological-update-monkeypox-multi-country-outbreak
  7. UK Health Security Agency (UKHSA). Monkeypox: Case Definitions. London: UKHSA; Published: 20 May 2022; Updated: 24 May 2022. [Accessed 26 May 2022]. Available from: https://www.gov.uk/guidance/monkeypox-case-definitions
  8. UK Health Security Agency (UKHSA). Monkeypox contact tracing guidance: classification of contacts and advice for vaccination and follow up. London: UKHSA; Published: 20 May 2022. [Accessed 26 May 2022]. Available from: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1077329/20220520_monkeypox-contact-tracing-classification-and-vaccination-matrix.pdf
  9. Beer EM, Rao VB. A systematic review of the epidemiology of human monkeypox outbreaks and implications for outbreak strategy. PLoS Negl Trop Dis. 2019;13(10):e0007791.  https://doi.org/10.1371/journal.pntd.0007791  PMID: 31618206 
  10. World Health Organization Regional Office for Europe (WHO/Europe). Health emergencies. Monkeypox cases reported in the European Region. Copenhagen: WHO/Europe; Published: 20 May 2022. [Accessed 26 May 2022]. Available from: https://www.euro.who.int/en/health-topics/health-emergencies/pages/news/news/2022/05/monkeypox-cases-reported-in-the-who-european-region
  11. Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. The changing epidemiology of human monkeypox-A potential threat? A systematic review. PLoS Negl Trop Dis. 2022;16(2):e0010141.  https://doi.org/10.1371/journal.pntd.0010141  PMID: 35148313 

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