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Abstract

The extent of monkeypox virus environmental contamination of surfaces is unclear. We examined surfaces in rooms occupied by two monkeypox patients on their fourth hospitalisation day. Contamination with up to 105 viral copies/cm2 on inanimate surfaces was estimated by PCR and the virus was successfully isolated from surfaces with more than 106 copies. These data highlight the importance of strict adherence of hospital staff to recommended protective measures. If appropriate, pre-exposure or early post-exposure vaccination should be considered for individuals at risk.

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/content/10.2807/1560-7917.ES.2022.27.26.2200477
2022-06-30
2024-12-11
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.26.2200477
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References

  1. Zumla A, Valdoleiros SR, Haider N, Asogun D, Ntoumi F, Petersen E, et al. Monkeypox outbreaks outside endemic regions: scientific and social priorities. Lancet Infect Dis. 2022;S1473309922003541.  https://doi.org/10.1016/S1473-3099(22)00354-1  PMID: 35636447 
  2. World Health Organization (WHO). Multi-country monkeypox outbreak in non-endemic countries. Geneva: WHO; 21 May 2022. Available from: https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON385
  3. Bunge EM, Hoet B, Chen L, Lienert F, Weidenthaler H, Baer LR, et al. The changing epidemiology of human monkeypox-A potential threat? A systematic review. PLoS Negl Trop Dis. 2022;16(2):e0010141.  https://doi.org/10.1371/journal.pntd.0010141  PMID: 35148313 
  4. Centers for Disease Control and Prevention (CDC). Human monkeypox--Kasai Oriental, Zaire, 1996-1997. MMWR Morb Mortal Wkly Rep. 1997;46(14):304-7. PMID: 9132583 
  5. Nakoune E, Lampaert E, Ndjapou SG, Janssens C, Zuniga I, Van Herp M, et al. A Nosocomial outbreak of human monkeypox in the Central African Republic. Open Forum Infect Dis. 2017;4(4):ofx168. PMID: 29732376 
  6. Vaughan A, Aarons E, Astbury J, Brooks T, Chand M, Flegg P, et al. Human-to-Human Transmission of Monkeypox Virus, United Kingdom, October 2018. Emerg Infect Dis. 2020;26(4):782-5.  https://doi.org/10.3201/eid2604.191164  PMID: 32023204 
  7. Kozlov M. Monkeypox outbreaks: 4 key questions researchers have. Nature. 2022;606(7913):238-9.  https://doi.org/10.1038/d41586-022-01493-6  PMID: 35624160 
  8. Nörz D, Tang HT, Emmerich P, Giersch K, Fischer N, Addo M, et al. Rapid adaptation of established high-throughput molecular testing infrastructure for detection of monkeypoxvirus.http://medrxiv.org/lookup/doi/10.1101/2022.06.05.22276011 https://doi.org/10.1101/2022.06.05.22276011 
  9. Nicas M, Hubbard AE, Jones RM, Reingold AL. The Infectious Dose of Variola (Smallpox) Virus. Appl Biosaf. 2004;9(3):118-27.  https://doi.org/10.1177/153567600400900302 
  10. Reynolds MG, McCollum AM, Nguete B, Shongo Lushima R, Petersen BW. Improving the Care and Treatment of Monkeypox Patients in Low-Resource Settings: Applying Evidence from Contemporary Biomedical and Smallpox Biodefense Research. Viruses. 2017;9(12):380.  https://doi.org/10.3390/v9120380  PMID: 29231870 
  11. Johnson RF, Dyall J, Ragland DR, Huzella L, Byrum R, Jett C, et al. Comparative analysis of monkeypox virus infection of cynomolgus macaques by the intravenous or intrabronchial inoculation route. J Virol. 2011;85(5):2112-25.  https://doi.org/10.1128/JVI.01931-10  PMID: 21147922 
  12. Rheinbaben F v., Gebel J, Exner M, Schmidt A. Environmental resistance, disinfection, and sterilization of poxviruses. In: Mercer AA, Schmidt A, Weber O, Herausgeber. Poxviruses. Basel: Birkhäuser Basel; 2007. p. 397-405.
  13. Robert Koch Institut (RKI). Empfehlungen des RKI zu Hygienemaßnahmen im Rahmen der Behandlung und Pflege von Patienten mit einer Infektion durch Affenpockenviren in Einrichtungen des Gesundheitswesens. [RKI recommendations on infection prevention measures in the treatment and care of patients with monkeypox virus infection in healthcare facilities]. Berlin: RKI; 30 May 2022. German. Available from: https://www.rki.de/DE/Content/InfAZ/A/Affenpocken/Hygiene.html;jsessionid=D85BBDF59B959B18CA79DC51CBFFA2AE.internet062?nn=2386228#doc16733606bodyText6
  14. Casanova LM, Rutala WA, Weber DJ, Sobsey MD. Effect of single- versus double-gloving on virus transfer to health care workers’ skin and clothing during removal of personal protective equipment. Am J Infect Control. 2012;40(4):369-74.  https://doi.org/10.1016/j.ajic.2011.04.324  PMID: 21831480 
  15. Garrido-Molina JM, Márquez-Hernández VV, Alcayde-García A, Ferreras-Morales CA, García-Viola A, Aguilera-Manrique G, et al. Disinfection of gloved hands during the COVID-19 pandemic. J Hosp Infect. 2021;107:5-11.  https://doi.org/10.1016/j.jhin.2020.09.015  PMID: 32949629 
  16. Scheithauer S, Häfner H, Seef R, Seef S, Hilgers RD, Lemmen S. Disinfection of gloves: feasible, but pay attention to the disinfectant/glove combination. J Hosp Infect. 2016;94(3):268-72.  https://doi.org/10.1016/j.jhin.2016.08.007  PMID: 27597264 
  17. Mahase E. Monkeypox: Healthcare workers will be offered smallpox vaccine as UK buys 20 000 doses. BMJ. 2022;377:o1379.  https://doi.org/10.1136/bmj.o1379  PMID: 35649575 
  18. Robert Koch Institut (RKI). Beschluss der STIKO für die Empfehlung zur Impfung gegen Affenpocken mit Imvanex (MVA-Impfstoff). [Resolution of the STIKO for the recommendation to vaccinate against monkeypox with Imvanex (modified vaccinia virus (MVA) vaccine)]. Berlin: RKI; 21 Jun 2022. German. Available from: https://www.rki.de/DE/Content/Infekt/EpidBull/Archiv/2022/25-26/Art_01.pdf?__blob=publicationFile
  19. European Centre for Disease Prevention and Control (ECDC). Factsheet for health professionals on monkeypox. Stockholm: ECDC; 19 Jun 2022. Available from: https://www.ecdc.europa.eu/en/all-topics-z/monkeypox/factsheet-health-professionals
  20. UK Health Security Agency (UKHSA). Guidance. Monkeypox: infected people who are isolating at home. London: UKHSA; 9 Jun 2022. Last updated 17 Jun 2022. Available from: https://www.gov.uk/guidance/guidance-for-people-with-monkeypox-infection-who-are-isolating-at-home#how-to-isolate-safely-at-home-if-you-have-monkeypox-infection
  21. Centers for disease control and prevention (CDC). Interim Guidance for Household Disinfection of Monkeypox Virus. Atlanta: CDC; 6 Jun 2022. Available from: https://www.cdc.gov/poxvirus/monkeypox/pdf/monkeypox-interim-guidance-for-household-disinfection-508.pdf
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