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Abstract

From July 2022, cases of imported diphtheria with toxigenic remarkably increased among migrants arriving in Germany. Up to 30 September 2022, 44 cases have been reported to the national public health institute, all laboratory-confirmed, male, and mainly coming from Syria (n = 21) and Afghanistan (n = 17). Phylogeny and available journey information indicate that most cases (n = 19) were infected along the Balkan route. Active case finding, increased laboratory preparedness and epicentre localisation in countries along this route are important.

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/content/10.2807/1560-7917.ES.2022.27.46.2200849
2022-11-17
2022-12-10
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.46.2200849
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References

  1. Robert Koch Institute (RKI). Häufung von Fällen mit Hautdiphtherie in Deutschland und Europa. [Upsurge of cases of cutaneous diphtheria in Germany and Europe]. Epidemiol Bull. 2022; (36):27-8. Available from: https://www.rki.de/DE/Content/Infekt/EpidBull/Archiv/2022/Ausgaben/36_22.pdf
  2. European Centre for Disease Prevention and Control (ECDC). Increase of reported diphtheria cases among migrants in Europe due to Corynebacterium diphtheriae, 2022 – 06 October 2022. Stockholm: ECDC; 2022. Available from: https://www.ecdc.europa.eu/en/publications-data/increase-reported-diphtheria-cases-among-migrants-europe-due-corynebacterium
  3. Robert Koch Institute (RKI). Falldefinitionen des Robert Koch-Instituts zur Übermittlung von Erkrankungs- oder Todesfällen und Nachweisen von Krankheitserregern. [Case definitions of RKI for reporting of cases of disease or death and confirmation of pathogens]. Berlin: RKI; 2019. Available from: www.rki.de/falldefinitionen
  4. Robert Koch Institute (RKI). RKI-Ratgeber Diphtherie. [RKI recommendations on diphtheria]. Berlin: RKI; 2018. [Accessed 10 Nov 2022]. Available from: https://www.rki.de/DE/Content/Infekt/EpidBull/Merkblaetter/Ratgeber_Diphtherie.html
  5. Berger A, Dangel A, Schober T, Schmidbauer B, Konrad R, Marosevic D, et al. Whole genome sequencing suggests transmission of Corynebacterium diphtheriae-caused cutaneous diphtheria in two siblings, Germany, 2018. Euro Surveill. 2019;24(2):1-4.  https://doi.org/10.2807/1560-7917.ES.2019.24.2.1800683  PMID: 30646974 
  6. Kofler J, Ramette A, Iseli P, Stauber L, Fichtner J, Droz S, et al. Ongoing toxin-positive diphtheria outbreaks in a federal asylum centre in Switzerland, analysis July to September 2022. Euro Surveill. 2022;27(44):1-5.  https://doi.org/10.2807/1560-7917.ES.2022.27.44.2200811  PMID: 36330823 
  7. Robert Koch Institute (RKI). Infektionsepidemiologisches Jahrbuch meldepflichtiger Krankheiten für 2020. [Yearbook of notifiable diseases 2020]. Berlin: RKI; 2021. Available from: www.rki.de/jahrbuch
  8. Konrad R, Berger A, Huber I, Boschert V, Hörmansdorfer S, Busch U, et al. Matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) mass spectrometry as a tool for rapid diagnosis of potentially toxigenic Corynebacterium species in the laboratory management of diphtheria-associated bacteria. Euro Surveill. 2010;15(43):1-5.  https://doi.org/10.2807/ese.15.43.19699-en  PMID: 21087580 
  9. World Health Organization (WHO). Diphtheria reported cases and incidence. Geneva: WHO. [Accessed 9 Oct 2022]. Available from: https://immunizationdata.who.int/pages/incidence/diphtheria.html
  10. World Health Organization (WHO). Immunization dashboard. Most recent update: 15 July 2022. Geneva: WHO; 2022. [Accessed 9 Nov 2022]. Available from: https://immunizationdata.who.int/pages/coverage/dtp.html
  11. Bundesamt für Migration und Flüchtlinge (BAMF) [Federal Office for Migration and Refugees]. Aktuelle Zahlen. Ausgabe: Juli 2022. [Update asylum seekers, July 2022]. Nürnberg: BAMF; 2022. Available from: https://www.bamf.de/SharedDocs/Anlagen/DE/Statistik/AsylinZahlen/aktuelle-zahlen-juli-2022.pdf
  12. Bundesamt für Migration und Flüchtlinge (BAMF) [Federal Office for Migration and Refugees]. Aktuelle Zahlen. Ausgabe: August 2022. [Update asylum seekers, August 2022]. Nürnberg: BAMF; 2022. Available from: https://www.bamf.de/SharedDocs/Anlagen/DE/Statistik/AsylinZahlen/aktuelle-zahlen-august-2022.pdf
  13. Bundesamt für Migration und Flüchtlinge (BAMF) [Federal Office for Migration and Refugees]. Aktuelle Zahlen. Ausgabe: September 2022. [Update asylum seekers, September 2022]. Nürnberg: BAMF; 2022.
  14. European Union Agency for Asylum (EUAA). Asylum Report 2022. Luxembourg: EUAA; 2022. Available from: https://euaa.europa.eu/publications/asylum-report-2022
  15. World Health Organization (WHO). Monkeypox outbreak 2022 - Global. Geneva: WHO; 2022. [Accessed 9 Nov 2022]. Available from: https://www.who.int/emergencies/situations/monkeypox-oubreak-2022
  16. Robert Koch Institute (RKI). Management von Ausbrüchen in Gemeinschaftsunterkünften für Geflüchtete. [Management of outbreaks in shared accommodations for migrants]. Berlin: RKI; 2022. Available from: https://www.rki.de/DE/Content/GesundAZ/F/Flucht/Management_Ausbruch.pdf
  17. Badell E, Alharazi A, Criscuolo A, Almoayed KAA, Lefrancq N, Bouchez V, et al. , NCPHL diphtheria outbreak working group. Ongoing diphtheria outbreak in Yemen: a cross-sectional and genomic epidemiology study. Lancet Microbe. 2021;2(8):e386-96.  https://doi.org/10.1016/S2666-5247(21)00094-X  PMID: 35544196 
  18. Dangel A, Berger A, Konrad R, Bischoff H, Sing A. Geographically diverse clusters of nontoxigenic corynebacterium diphtheriae infection, Germany, 2016-2017. Emerg Infect Dis. 2018;24(7):1239-45.  https://doi.org/10.3201/eid2407.172026  PMID: 29912709 
  19. European Centre for Disease Prevention and Control (ECDC). Outbreak Investigations. Stockholm: ECDC. [Accessed 9 Oct 2022]. Available from: https://wiki.ecdc.europa.eu/fem/Pages/Outbreak%20Investigations.aspx
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