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Abstract

During predominant circulation of SARS-CoV-2 Omicron XBB.1.5 and other XBB sublineages (April–June 2023), we found that a second or third booster of Comirnaty bivalent Original/Omicron BA.4-5 mRNA vaccine, versus a first booster received at least 120 days earlier, was effective in preventing severe COVID-19 for more than 6 months post-administration in persons 60 years and above. In view of autumn 2023 vaccination campaigns, use of bivalent Original/Omicron BA.4-5 mRNA vaccines might be warranted until monovalent COVID-19 vaccines targeting Omicron XBB.1 sublineages become available.

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/content/10.2807/1560-7917.ES.2023.28.32.2300397
2023-08-10
2024-06-25
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2023.28.32.2300397
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/content/10.2807/1560-7917.ES.2023.28.32.2300397
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