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Abstract

Since autumn 2022, observed numbers of paediatric invasive group A infections in Portugal (n = 89) were higher than in pre-COVID-19 seasons. Between September 2022 and May 2023, the dominant diagnoses were pneumonia (25/79), mostly with empyema (20/25), and sepsis (22/79). A number of cases required admission to intensive care (27/79) and surgery (35/79), and the case fatality rate was 5.1% (4/79). Genomic sequencing (n = 55) revealed multiple genetic lineages, dominated by the M1 sublineage (26/55) and more diverse 12 isolates (12/55).

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/content/10.2807/1560-7917.ES.2023.28.36.2300427
2023-09-07
2024-04-27
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2023.28.36.2300427
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Sustained increase of paediatric invasive Streptococcus pyogenes infections dominated by M1UK and diverse emm12 isolates, Portugal, September 2022 to May 2023
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Catarina+Gouveia&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Gouveia Catarina</a>, <a href="/search?value1=Maria+Paula+Bajanca-Lavado&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bajanca-Lavado Maria Paula</a>, <a href="/search?value1=Rafael+Mamede&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mamede Rafael</a>, <a href="/search?value1=Ana+Ara%C3%BAjo+Carvalho&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Araújo Carvalho Ana</a>, <a href="/search?value1=Fernanda+Rodrigues&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rodrigues Fernanda</a>, <a href="/search?value1=Jos%C3%A9+Melo-Cristino&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Melo-Cristino José</a>, <a href="/search?value1=Mario+Ramirez&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ramirez Mario</a>, <a href="/search?value1=Ana+Fri%C3%A3es&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Friães Ana</a>, <a href="/search?value1=Portuguese+Group+for+the+Study+of+Streptococcal+Infections&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Portuguese Group for the Study of Streptococcal Infections</a>, <a href="/search?value1=Portuguese+Study+Group+of+Pediatric+Invasive+Streptococcal+Disease&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Portuguese Study Group of Pediatric Invasive Streptococcal Disease</a></span>. Sustained increase of paediatric invasive Streptococcus pyogenes infections dominated by M1UK and diverse emm12 isolates, Portugal, September 2022 to May 2023. <a href="/content/ecdc">Euro Surveill.</a> 2023;28(36):pii=2300427. <a href="https://doi.org/10.2807/1560-7917.ES.2023.28.36.2300427" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2023.28.36.2300427</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 14 Aug 2023;&nbsp;&nbsp; <span class="generated">Accepted</span>: 07 Sept 2023 </span> </p>
/content/10.2807/1560-7917.ES.2023.28.36.2300427
/content/10.2807/1560-7917.ES.2023.28.36.2300427
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