1887
  1. Home
  2. Eurosurveillance
  3. Volume 28, Issue 8, 23/Feb/2023
  4. Article
Rapid communication Open Access
Like 0
Download

Abstract

In autumn 2022, the Spanish Influenza National Reference Laboratory (NRL) confirmed the detection of influenza A(H5N1) in samples from two asymptomatic workers linked to an outbreak in a poultry farm in Spain. Nasopharyngeal swabs were taken according to a national screening protocol for exposed workers. Absence of symptoms, low viral load and negative serology in both workers suggested environmental contamination. These findings motivated an update of the early detection strategy specifying timing and sampling conditions in asymptomatic exposed persons.

© Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Loading

Article metrics loading...

/content/10.2807/1560-7917.ES.2023.28.8.2300107
2023-02-23
2025-05-21
/content/10.2807/1560-7917.ES.2023.28.8.2300107
Loading
Loading full text...

Full text loading...

/deliver/fulltext/eurosurveillance/28/8/eurosurv-28-8-1.html?itemId=/content/10.2807/1560-7917.ES.2023.28.8.2300107&mimeType=html&fmt=ahah

References

  1. Adlhoch C, Fusaro A, Gonzales JL, Kuiken T, Marangon S, Niqueux É, et al. Avian influenza overview September - December 2022. EFSA J. 2023;21(1):e07786. PMID: 36698491 
  2. Ministerio de Agricultura, Pesca y Alimentación. Se detecta un segundo foco de influenza aviar de alta patogenicidad (IAAP) H5N1 en una granja de gallinas ponedores en Guadalajara. [A second outbreak of high avian influenza pathogenicity (hpai) h5n1 is detected in a laying hen farm in Guadalajara.] Madrid: Subdirección General de Sanidad e Higiene Animal y Trazabilidad; 2022. Spanish. Available from: https://www.mapa.gob.es/es/ganaderia/temas/sanidad-animal-higiene-ganadera/iaapactualizacionfocos20092022r_tcm30-628242.pdf
  3. Ministerio de Agrigultura Pesca y Alimentación. Manual práctico de operaciones en la lucha contra la influenza aviar. [Practical manual of operations in the fight against the avian influenza]. Madrid: Subdirección General de Sanidad e Higiene Animal y Trazabilidad; 2022. Spanish. Available from: https://www.mapa.gob.es/es/ganaderia/temas/sanidad-animal-higiene-ganadera/manualiaabril2022_tcm30-437988.pdf
  4. Ministerio de Sanidad. Prevención, detección precoz y actuaciones frente a la gripe aviar. [Prevention, early detection and actions against avian influenza]. Madrid: Gobierno de Espana; 2022. Spanish. Available from: https://www.sanidad.gob.es/profesionales/saludPublica/ccayes/alertasActual/docs/20220304_Vigilancia_prevencion_gripe_aviar.pdf
  5. Garcia-Garcia ML, Calvo C, Ruiz S, Pozo F, Del Pozo V, Remedios L, et al. Role of viral coinfections in asthma development. PLoS One. 2017;12(12):e0189083.  https://doi.org/10.1371/journal.pone.0189083  PMID: 29206851 
  6. Zhou B, Donnelly ME, Scholes DT, St George K, Hatta M, Kawaoka Y, et al. Single-reaction genomic amplification accelerates sequencing and vaccine production for classical and Swine origin human influenza a viruses. J Virol. 2009;83(19):10309-13.  https://doi.org/10.1128/JVI.01109-09 
  7. Elbe S, Buckland-Merrett G. Data, disease and diplomacy: GISAID’s innovative contribution to global health. Glob Chall. 2017;1(1):33-46.  https://doi.org/10.1002/gch2.1018 
  8. World Organisation for Animal Health (WOAH). High Pathogenicity Avian Influenza (HPAI)-Situation Report. Paris: WOAH; 2022. Available from: https://www.woah.org/app/uploads/2022/10/hpai-situation-report-20221020.pdf
  9. World Health Organization (WHO). Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003-2021. Geneva: WHO; 2021. Available from: https://www.who.int/publications/m/item/cumulative-number-of-confirmed-human-cases-for-avian-influenza-a(h5n1)-reported-to-who-2003-2021-15-april-2021
  10. CIDRAP News. Spain reports first avian flu case in birds. Minneapolis: University of Minnesota; 7 Jul 2006. Available from: https://www.cidrap.umn.edu/avian-influenza-bird-flu/spain-reports-first-avian-flu-case-birds
  11. European Center for Disease Prevention and Control (ECDC). Testing and detection of zoonotic influenza virus infections in humans in the EU/EEA, and occupational safety and health measures for those exposed at work. Stockholm: ECDC; 2022. Available from https://www.ecdc.europa.eu/en/publications-data/zoonotic-influenza-virus-infections-humans-testing-and-detection
  12. Haut Conseil de la Sante Publique. Avis relatif à la prévention de la transmission à l’homme des virus influenza porcins et aviaires. [Statement on the prevention of transmission of swine and avian influenza viruses to humans]. Paris: Haut Conseil de la Sante Publique; 10 Dec 2021. French. Available from: https://www.hcsp.fr/Explore.cgi/AvisRapportsDomaine?clefr=1142
  13. Terveyden ja hyvinvoinnin laitos (THL). Toimenpideohje ihmisen lintuinfluenssatartuntojen torjumiseksi. [Guidelines for the control of avian influenza infections in humans]. Helsinki: THL. [Accessed: 10 Oct 2022]. Finnish. Available from: https://thl.fi/fi/web/infektiotaudit-ja-rokotukset/taudit-ja-torjunta/taudit-ja-taudinaiheuttajat-a-o/lintuinfluenssa/toimenpideohje-ihmisen-lintuinfluenssatartuntojen-torjumiseksi
  14. Health Protection Surveillance Centre (HPSC). Guidance on public health actions to be taken on notification of Avian Influenza (AI) in poultry and wild birds in Ireland. Dublin: HPSC; 2017. Available from: https://www.hpsc.ie/a-z/respiratory/influenza/pandemicinfluenza/guidance/pandemicinfluenzapreparednessforireland/supplement11tochapter11part1/2017%20Supplement%2011Part%201.pdf
  15. European Centre for Disease Prevention and Control (ECDC). EU case definitions. Stockholm: ECDC. [Accessed: 23 Dec 2022]. Available from: https://www.ecdc.europa.eu/en/all-topics/eu-case-definitions
  16. Ministerio de Sanidad. Prevención, detección precoz y control de gripe aviar en personas expuestas a focos en aves y visones [Prevention, early detection and control of avian influenza in persons exposed to outbreaks in birds and mink]. Madrid: Gobierno de Espana; 2023. Spanish. Available from: https://www.sanidad.gob.es/profesionales/saludPublica/ccayes/alertasActual/docs/20230203_Vigilancia_prevencion_gripe_aviar.pdf
Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Esteban+Aznar&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Aznar Esteban</a>, <a href="/search?value1=Inmaculada+Casas&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Casas Inmaculada</a>, <a href="/search?value1=Alejandro+Gonz%C3%A1lez+Praetorius&option1=author&noRedirect=true" class="nonDisambigAuthorLink">González Praetorius Alejandro</a>, <a href="/search?value1=Mar%C3%ADa+Jos%C3%A9+Ruano+Ramos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ruano Ramos María José</a>, <a href="/search?value1=Francisco+Pozo&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pozo Francisco</a>, <a href="/search?value1=Mar%C3%ADa+Jos%C3%A9+Sierra+Moros&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sierra Moros María José</a>, <a href="/search?value1=Mar%C3%ADa+Victoria+Garc%C3%ADa+Rivera&option1=author&noRedirect=true" class="nonDisambigAuthorLink">García Rivera María Victoria</a>, <a href="/search?value1=Azucena+S%C3%A1nchez+S%C3%A1nchez&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sánchez Sánchez Azucena</a>, <a href="/search?value1=Elena+Garc%C3%ADa+Villacieros&option1=author&noRedirect=true" class="nonDisambigAuthorLink">García Villacieros Elena</a>, <a href="/search?value1=Gabriela+Saravia&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Saravia Gabriela</a>, <a href="/search?value1=Mar%C3%ADa+Iglesias-Caballero&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Iglesias-Caballero María</a>, <a href="/search?value1=Elena+Rom%C3%A1n+Marcos&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Román Marcos Elena</a>, <a href="/search?value1=Luc%C3%ADa+Garc%C3%ADa+San+Miguel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">García San Miguel Lucía</a></span>. Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination. <a href="/content/ecdc">Euro Surveill.</a> 2023;28(8):pii=2300107. <a href="https://doi.org/10.2807/1560-7917.ES.2023.28.8.2300107" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2023.28.8.2300107</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 13 Feb 2023;&nbsp;&nbsp; <span class="generated">Accepted</span>: 23 Feb 2023 </span> </p>
/content/10.2807/1560-7917.ES.2023.28.8.2300107
/content/10.2807/1560-7917.ES.2023.28.8.2300107
Loading

Data & Media loading...

Submit comment
Close
Comment moderation successfully completed
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error