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Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination
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Esteban Aznar1,*
, Inmaculada Casas2,* , Alejandro González Praetorius3 , María José Ruano Ramos4 , Francisco Pozo2 , María José Sierra Moros1,5 , María Victoria García Rivera6 , Azucena Sánchez Sánchez4 , Elena García Villacieros7 , Gabriela Saravia1 , María Iglesias-Caballero2 , Elena Román Marcos6,** , Lucía García San Miguel1,**
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View Affiliations Hide AffiliationsAffiliations: 1 Coordinating Centre for Health Alerts and Emergencies, Ministry of Health, Madrid, Spain 2 Influenza and Respiratory Unit, National Centre for Microbiology, Instituto de Salud Carlos III, Madrid, Spain 3 Microbiology laboratory, Hospital General Universitario de Guadalajara, Guadalajara, Spain 4 Laboratorio Central de Veterinaria, Ministerio de Agricultura, Pesca y Alimentación, Algete, Spain 5 CIBER in Infectious Diseases (CIBERINFEC), Madrid, Spain 6 Consejería de Sanidad de la Junta de Castilla-La Mancha, Dirección General de Salud Pública, Departamento de Epidemiología, Toledo, Spain 7 Subdirección General de Sanidad e Higiene Animal y Trazabilidad, Ministerio de Agricultura, Pesca y Alimentación, Madrid, Spain* These authors contributed equally to this work and share first authorship.** These authors contributed equally to this work and share last authorship.Correspondence:Esteban Aznareaznar sanidad.gob.es
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Citation style for this article: Aznar Esteban, Casas Inmaculada, González Praetorius Alejandro, Ruano Ramos María José, Pozo Francisco, Sierra Moros María José, García Rivera María Victoria, Sánchez Sánchez Azucena, García Villacieros Elena, Saravia Gabriela, Iglesias-Caballero María, Román Marcos Elena, García San Miguel Lucía. Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination. Euro Surveill. 2023;28(8):pii=2300107. https://doi.org/10.2807/1560-7917.ES.2023.28.8.2300107 Received: 13 Feb 2023; Accepted: 23 Feb 2023
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Abstract
In autumn 2022, the Spanish Influenza National Reference Laboratory (NRL) confirmed the detection of influenza A(H5N1) in samples from two asymptomatic workers linked to an outbreak in a poultry farm in Spain. Nasopharyngeal swabs were taken according to a national screening protocol for exposed workers. Absence of symptoms, low viral load and negative serology in both workers suggested environmental contamination. These findings motivated an update of the early detection strategy specifying timing and sampling conditions in asymptomatic exposed persons.

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