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Abstract

Chikungunya virus re-emerged on Réunion Island in August 2024, 18 years after a first major outbreak. Analysis of 173 genomes from the current epidemic reveals a monophyletic clade with mutations linked to adaptation to mosquitoes, including E1-A226V. Bayesian inference suggests only brief cryptic circulation before detection. The same lineage was also detected on Mayotte Island in March 2025. Continued spread and confirmed travel-related cases in mainland France and globally highlight the risk of wider regional and international dissemination.

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/content/10.2807/1560-7917.ES.2025.30.22.2500344
2025-06-05
2025-06-08
/content/10.2807/1560-7917.ES.2025.30.22.2500344
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Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Etienne+Frumence&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Frumence Etienne</a>, <a href="/search?value1=G%C3%A9raldine+Piorkowski&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Piorkowski Géraldine</a>, <a href="/search?value1=Nicolas+Traversier&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Traversier Nicolas</a>, <a href="/search?value1=Rayane+Amaral&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Amaral Rayane</a>, <a href="/search?value1=Muriel+Vincent&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Vincent Muriel</a>, <a href="/search?value1=Ambroise+Mercier&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Mercier Ambroise</a>, <a href="/search?value1=Nazli+Ayhan&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Ayhan Nazli</a>, <a href="/search?value1=Laurent+Souply&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Souply Laurent</a>, <a href="/search?value1=Laura+Pezzi&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Pezzi Laura</a>, <a href="/search?value1=Cl%C3%A9ment+Lier&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Lier Clément</a>, <a href="/search?value1=Gilda+Grard&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Grard Gilda</a>, <a href="/search?value1=Guillaume+Andr%C3%A9+Durand&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Durand Guillaume André</a>, <a href="/search?value1=Chikungunya+genomics+diagnostic+laboratory+network&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Chikungunya genomics diagnostic laboratory network </a>, <a href="/search?value1=Xavier+Deparis&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Deparis Xavier</a>, <a href="/search?value1=Fabian+Thouillot&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Thouillot Fabian</a>, <a href="/search?value1=Xavier+de+Lamballerie&option1=author&noRedirect=true" class="nonDisambigAuthorLink">de Lamballerie Xavier</a>, <a href="/search?value1=Raphaelle+Klitting&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Klitting Raphaelle</a>, <a href="/search?value1=Marie-Christine+Jaffar-Bandjee&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Jaffar-Bandjee Marie-Christine</a></span>. Genomic insights into the re-emergence of chikungunya virus on Réunion Island, France, 2024 to 2025. <a href="/content/ecdc">Euro Surveill.</a> 2025;30(22):pii=2500344. <a href="https://doi.org/10.2807/1560-7917.ES.2025.30.22.2500344" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2025.30.22.2500344</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 21 May 2025;&nbsp;&nbsp; <span class="generated">Accepted</span>: 05 Jun 2025 </span> </p>
/content/10.2807/1560-7917.ES.2025.30.22.2500344
/content/10.2807/1560-7917.ES.2025.30.22.2500344
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